Mus caroli (Ryukyu mouse): 110286532
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Entry
110286532 CDS
T05910
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00010
Glycolysis / Gluconeogenesis
mcal00020
Citrate cycle (TCA cycle)
mcal00620
Pyruvate metabolism
mcal00785
Lipoic acid metabolism
mcal01100
Metabolic pathways
mcal01200
Carbon metabolism
mcal01210
2-Oxocarboxylic acid metabolism
mcal04066
HIF-1 signaling pathway
mcal04922
Glucagon signaling pathway
mcal05230
Central carbon metabolism in cancer
mcal05415
Diabetic cardiomyopathy
Module
mcal_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110286532 (Pdha1)
00020 Citrate cycle (TCA cycle)
110286532 (Pdha1)
00620 Pyruvate metabolism
110286532 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110286532 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110286532 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110286532 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110286532 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110286532 (Pdha1)
Enzymes [BR:
mcal01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110286532 (Pdha1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
110286532
NCBI-ProteinID:
XP_021008595
Ensembl:
MGP_CAROLIEiJ_G0033536
UniProt:
A0A6P5P463
LinkDB
All DBs
Position
X:complement(148576600..148592149)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGTAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVSTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LXELGYHIYSSDAPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgctgtatcccgcgtgttggcaggcactgcgcagaagccggca
agccgggtgctggttgcttcccggaattttgcaaacgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcagcacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcgccggatggagctaaaggcggatcag
ctgtataagcagaaaatcattcgtggtttctgtcatttgtgtgatggtcaggaagcctgc
tgcgtgggcctggaggctggcataaaccccacggaccacctcatcaccgcctatcgagca
catggcttcaccttcactcggggcctgcctgtgcgagcaattcttgcagagctaacagga
agaagaggaggttgtgctaaagggaaaggcgggtcaatgcacatgtacgccaagaacttc
tatggaggcaatggcatcgttggagctcaggtgcccctgggagcaggaattgccctggcc
tgcaagtacaatggaaaagatgaggtctgtttgacattatacggcgatggtgctgctaat
cagggtcagatctttgaagcttacaatatggcagcactgtggaaattaccttgcattttt
atctgtgagaacaaccgctatggcatggggacgtctgttgagagagcagcagccagcacg
gactactacaaaagaggagattttattcctggactcagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcctattgcaggtctggtaaggggcccatc
ctgatggagctacagacttaccgctaccatggacacagcatgagtgaccctggagtaagc
taccgcactcgagaagaaatccaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaggatgctgcccagtttgccacggctgatcctgagcccccg
ttgnaggaactaggctatcacatctacagcagtgacgctccctttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
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