Mus caroli (Ryukyu mouse): 110300622 Help Entry 110300622         CDS       T05910                                  Symbol Insr Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism mcal  Mus caroli (Ryukyu mouse) Pathway mcal04010   MAPK signaling pathway mcal04014   Ras signaling pathway mcal04015   Rap1 signaling pathway mcal04022   cGMP-PKG signaling pathway mcal04066   HIF-1 signaling pathway mcal04068   FoxO signaling pathway mcal04072   Phospholipase D signaling pathway mcal04150   mTOR signaling pathway mcal04151   PI3K-Akt signaling pathway mcal04152   AMPK signaling pathway mcal04211   Longevity regulating pathway mcal04213   Longevity regulating pathway - multiple species mcal04520   Adherens junction mcal04910   Insulin signaling pathway mcal04913   Ovarian steroidogenesis mcal04923   Regulation of lipolysis in adipocytes mcal04930   Type II diabetes mellitus mcal04931   Insulin resistance mcal04932   Non-alcoholic fatty liver disease mcal04960   Aldosterone-regulated sodium reabsorption mcal05010   Alzheimer disease mcal05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mcal00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110300622 (Insr)    04014 Ras signaling pathway     110300622 (Insr)    04015 Rap1 signaling pathway     110300622 (Insr)    04066 HIF-1 signaling pathway     110300622 (Insr)    04068 FoxO signaling pathway     110300622 (Insr)    04072 Phospholipase D signaling pathway     110300622 (Insr)    04022 cGMP-PKG signaling pathway     110300622 (Insr)    04151 PI3K-Akt signaling pathway     110300622 (Insr)    04152 AMPK signaling pathway     110300622 (Insr)    04150 mTOR signaling pathway     110300622 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     110300622 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     110300622 (Insr)    04923 Regulation of lipolysis in adipocytes     110300622 (Insr)    04913 Ovarian steroidogenesis     110300622 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     110300622 (Insr)   09149 Aging    04211 Longevity regulating pathway     110300622 (Insr)    04213 Longevity regulating pathway - multiple species     110300622 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     110300622 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     110300622 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     110300622 (Insr)    04932 Non-alcoholic fatty liver disease     110300622 (Insr)    04931 Insulin resistance     110300622 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mcal01001]     110300622 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mcal04090]     110300622 (Insr) Enzymes [BR:mcal01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      110300622 (Insr) Protein kinases [BR:mcal01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    110300622 (Insr) CD molecules [BR:mcal04090]  Proteins   110300622 (Insr) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  110300622 NCBI-ProteinID:  XP_021026530 Ensembl:  MGP_CAROLIEiJ_G0030765 UniProt:  A0A6P5Q941 LinkDB All DBs Position 8:complement(14733..146807) Genome browser AA seq 1384 aa AA seqDB search MGFGRGCETTAVPLLVAVAALLVGTAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL GNCSEPDDPTKCVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHFKCRNSRKPG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQ ILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDSRPSRKRRSLEEVGNVTATTLTLP EFPNTSSTIVPTSQEEHRPYEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAA YVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKII IGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEV PREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVM KGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQ MTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLL PVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPP DNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLDPSFPEVSFFYSEENKAPESEELE MEFEDMENVPLDRSSHCLREEAGGREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPR SNPS NT seq 4155 nt NT seq  +upstreamnt  +downstreamnt atgggcttcgggagaggatgtgagacgacggctgtgccattgctggtggccgtggccgcg ttgctggtgggcacagccggccacctgtaccctggagaggtgtgccctggtatggacatc cggaacaacctgaccaggctacatgagctggagaactgctcagtcattgagggccatctg cagatcctcctgatgttcaagaccagacctgaagatttccgagacctcagtttccccaaa ctcatcatgatcacagactacctgcttctcttccgtgtctatggcctggaaagtctgaaa gacctcttcccaaacctcacagtcatccgaggctcccgtctctttttcaactatgccctg gttatcttcgagatggtccacctgaaggagctggggctttacaacctcatgaacatcacc cggggctctgtccgcatcgagaagaataatgagctctgctacctggccactatcgactgg tcccgtatcctggattctgtggaggacaactacattgtactgaacaaagatgacaacgag gaatgtggggatgtctgtccaggcactgccaagggaaagaccaactgccctgccaccgtc atcaatgggcagtttgtagaacggtgctggacacacagtcattgtcagaaagtttgccca accatctgtaagtcacatggctgcacagctgaaggcctatgctgccacaaggagtgcctg ggcaactgttcggaacctgatgaccccaccaagtgtgtggcctgtcgcaacttctatctg gatggtcagtgtgtggagacctgcccgccaccctactatcacttccaggactggcgctgt gtgaactttagcttctgccaagaccttcacttcaaatgcaggaactctcggaagcctggc tgccaccaatacgtcattcataacaacaagtgcatccccgagtgcccgtctggttatacc atgaattccagcaacttgatgtgcaccccatgtctgggaccctgccctaaggtctgccaa atcctcgaaggcgagaagaccattgattctgtgacatctgcccaggagctccgaggctgc actgtgatcaacggtagcctgatcatcaacatccgagggggcaacaacctggcagctgag ctggaggctaaccttggcctcattgaagaaatttcaggatttctaaagatccgccgctcc tatgctctggtatcactttctttcttcaggaagctacatctgattcgaggagagaccttg gaaattgggaactattctttctatgccttggacaaccagaacctgaggcaactctgggac tggagcaaacacaacctcaccatcactcagggcaagctcttcttccattacaacccgaaa ctctgcttgtctgaaattcacaagatggaagaggtctccggaactaagggccgccaggag aggaacgacattgccctgaagaccaatggagaccaggcatcgtgtgaaaatgaattgctt aaattttctttcattcggacatcttttgacaagatcctgctgagatgggaaccctactgg ccccccgacttccgagatctcctgggattcatgttgttctacaaagaggccccttatcag aacgtgacagagtttgatgggcaggatgcttgtggctccaacagctggactgtggtggat attgacccgccccagaggtccaatgaccccaagtctcagaccccaagtcaccctgggtgg ctgatgcggggcctcaaaccttggacccaatacgccatctttgtgaagaccttggttacc ttctctgatgaacggcggacttatggagccaaaagtgatatcatctatgtgcaaacagat gccaccaatccttctgtccccctggatcccatatcagtttctaattcctcatctcagatt atcttaaagtggaagcccccctctgaccccaatggcaacatcacacactacctggtgtac tgggagaggcaggcagaggacagcgagctgtttgagctggattattgtctcaaagggctg aagctcccttcacggacctggtccccaccttttgagtctgatgattctcagaagcacaat cagagtgagtatgacgactcggccagtgagtgctgctcatgccctaagactgactctcag atcctgaaggagctggaggagtcttcattcaggaagaccttcgaggattacctgcacaac gtggtttttgtccccagaaaaacctcttcaggcaatggtgccgaggacagtaggccatcc cgaaagcgaagatcccttgaagaggtggggaatgtgacagccaccacgctcacacttcca gagttccccaacacctcctccaccattgtgcccacaagccaggaggagcacaggccatat gagaaagtggtgaacaaggagtcacttgtcatttctggcctgagacacttcactgggtac cgcattgagctgcaggcatgcaatcaagattccccagatgagaggtgcagtgtggctgcc tacgtcagtgcccggaccatgcctgaagctaaggcagatgacatcgttggccctgtgacc catgaaatctttgagaacaatgttgtacacttaatgtggcaagagccaaaggaacctaat ggtctgattgtgttatatgaagtgagctatcgccgatatggtgatgaggagctgcacctc tgtgtctcccggaagcattttgccctggagcggggctgcaggctgcgagggctctcccca ggaaactacagtgttcgagtccgggctacctctctggcaggaaatggctcctggacagaa cccacttatttttatgtgactgattatttagatgtcccatcaaatattgccaaaattatt attgggcccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctattt ctgagaaagaggcagccggatgggccaatgggaccactgtatgcatcttcaaaccctgag tacctcagtgccagtgatgtgtttccatcttctgtgtacgtgccggacgagtgggaggta cctcgagagaagatcacccttcttcgagagctggggcagggatcctttggtatggtgtat gaaggcaatgccaaggatatcatcaagggtgaggcagagacccgtgttgcggtgaagaca gtcaatgaatcagccagtcttcgagaacggattgagttcctcaatgaggcatcagtcatg aagggtttcacctgccatcatgtggtccgccttcttggggtggtatccaaaggacagcca acactggtagtgatggaattgatggctcatggagacctgaaaagtcacctccgttctctg aggccagatgctgagaataacccaggccgccctccccctaccttgcaagaaatgattcag atgacagcagaaattgctgatggcatggcatacttgaacgccaagaagtttgtgcaccgg gacctggcagctcgaaactgcatggttgcccatgattttactgtcaaaattggagacttt ggaatgacaagggacatctacgagacagattactatcggaaagggggcaaggggctgctg cctgtgaggtggatgtcacctgagtccctgaaggatggagtctttactgcttcttctgat atgtggtcctttggggtggtcctttgggaaatcactagcctggctgagcaaccttatcaa ggcctgtctaatgaacaggtgttgaagtttgtcatggatggaggctatctggatccccct gataactgtccagagagactcactgacctgatgcgcatgtgctggcagttcaaccccaag atgaggccaaccttcctggaaatcgtcaacctgctcaaggatgacctcgaccccagcttt ccagaagtttccttcttctacagcgaggagaacaaggctcctgagagtgaggagctggag atggagtttgaggacatggagaatgtccccttggatcgttcctctcactgtctgagagaa gaggctgggggccgggagggagggtcctcactgagcatcaaacggacctatgatgaacac atcccctatacccacatgaatgggggcaagaagaacgggcgtgtcctcaccctgccaagg tcaaacccttcctaa

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