Mus caroli (Ryukyu mouse): 110304614
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Entry
110304614 CDS
T05910
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal01524
Platinum drug resistance
mcal03440
Homologous recombination
mcal03460
Fanconi anemia pathway
mcal04120
Ubiquitin mediated proteolysis
mcal04151
PI3K-Akt signaling pathway
mcal05206
MicroRNAs in cancer
mcal05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
110304614 (Brca1)
09124 Replication and repair
03440 Homologous recombination
110304614 (Brca1)
03460 Fanconi anemia pathway
110304614 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
110304614 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110304614 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
110304614 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
110304614 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mcal01009
]
110304614 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mcal04121
]
110304614 (Brca1)
03036 Chromosome and associated proteins [BR:
mcal03036
]
110304614 (Brca1)
03400 DNA repair and recombination proteins [BR:
mcal03400
]
110304614 (Brca1)
Enzymes [BR:
mcal01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
110304614 (Brca1)
Protein phosphatases and associated proteins [BR:
mcal01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
110304614 (Brca1)
Ubiquitin system [BR:
mcal04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
110304614 (Brca1)
Multi subunit Ring-finger type E3
BRCC complex
110304614 (Brca1)
Chromosome and associated proteins [BR:
mcal03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
110304614 (Brca1)
DNA repair and recombination proteins [BR:
mcal03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
110304614 (Brca1)
BRCA1-A complex
110304614 (Brca1)
BRCA1-B complex
110304614 (Brca1)
BRCA1-C complex
110304614 (Brca1)
BRCA complex
110304614 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
110304614 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
BRCT_2
zf-RING_UBOX
zf-RING_2
zf-C3HC4_4
zf-C3HC4_3
zf-RING_5
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
110304614
NCBI-ProteinID:
XP_021031691
Ensembl:
MGP_CAROLIEiJ_G0017223
UniProt:
A0A6P5QLK8
LinkDB
All DBs
Position
11:complement(97367656..97429426)
Genome browser
AA seq
1809 aa
AA seq
DB search
MDLSAARIQEVQSVLHAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNEITKRSLQGSTRFSQLVEELLKIMAAFELDTGMQVTNGFSFSKKKNNSCERLNE
EESIIQSVGYRNRVRRLPQVEPGNATLKDSLSVQVSNLGIVRSVKKNRQTQPRKKSVYIE
LDSDSSEETVTKPGDCSVRDRELLQTAPQEAGDEGKVRSAGEAACEFSEGIRNIEHHQCS
DDLNPTENHATERHPEKCQSISVSNVRVEPCGTDAHASSLQPETSSLLLIEDRMNAEKAE
FCNKSKQPGIAVSQQSRWAASKETCNDRQVPSTGEKVGPNADSLSDRKKWTHPQSLCPEN
SGPATDVSWITLNSSIQKVNEWFSRTGEMLTSDSASAGRHESNAEAAVVLEVSNEVDGGF
SSSRKTDLAAPDPHHTLMCKSGRDFSKPVENNINDKIFGKSYQRKGSRPHLNHVTEIIGT
FITEPQITQEQPFTNKLKRKRRTSLQPEDFIKKADSAGVQRTPDNTNQGAGPMEPHEQAV
STTSNCQENTIEGSNLQKERNACPTESLRKEPASTAGAKSKSNSVSDLEVELNVRSSKAP
KKNRLRKKSSTRCVLPLEPISRNPSPPTCAELEIDSCGSTEETKKNSSNQQPARHLREPQ
LIEDTEPAADAKKNEPNEHIRKRRASDAFPEEKLMNKAGLLTSCSSPRKSQGPVNPNPQK
TGTEQVETRQIPDSAKELRDQVLRGEPSGKTTDRSEESTSVSLVPDTDYDTQNSVSVLEA
NTVRYARTGSAQCMTQFVASENPKELVHGSNNAGSGTECLKPPLRHELNHSQEKVEMEDS
ELDTQYLQNTFQVSKRQSFALFSKPRSPQKDCASPKVTAKGKQKERQGQEEFEISHVQAV
AATVGLPVPCQEGKLAADTMCDRGSRLCPSSHYRSGENGLSATGKSGISQNSHFKQSVSP
TRSSIKIDNRKPLTEGRFEKHTSSTEKAVGNENILQSTVHTISLNNRGNACQEASSGSIH
EVCSTGDSFPGQLGRNRGPKVNTVLLLDSTQPGVCQQSVPVSDKYLEIKKQEGEAVCADF
SPCLFSDHLEQSMRSGKVFQVCSETPDDLLDDVEIQGHTSFGEGDVMERSAVFNGSILRR
ESSRSPSPVTHASKSRSLPRASRKLESSEESDSTEDEDLPCFQHLLSRISNTPELNRCSS
AVTQPMPEKAEGTQAPWKGSISDCNNEVIVIEASQEHQLSEDPRCSGSMFSSQHSAAQGS
TAIANSQDPNFNPPSKPRSHQSGNEEAFLSDKELISDNEEMATCLEEDNDQEEDSIVPDS
EASGYESETNLSEDCSQGDILTTQQRATMKYNLIKLQQEMAHLEAVLEQRGNQPSGHSPS
LLADPCALEDLPDLEPNMSGAAVLTSKNINENPVSQNLKSACDDKFQPQHREGPTGGDDE
SGMGRPSPFQSLLAGSRGSAHGRSRCLQKRRSPSQEELLQPAGSETSSEPHNSTGRSCLP
RQDLEGTPYLESGISLFSSRDPESESPKEPAHIGTTPASTSALKISQGQVAESFRSAAAA
GADKAVAGIVSKIKPELTSSEERADRDIAMVVSGLTPNEVMIVRKFAEKYRLTLTDAITE
ETTHVIIKTDAEFVCERTLKYFLGIAGGKWIVSYSWVVRSIQERKLLNVHEFEVKGDVVT
GRNHQGPRRSRESREKLFKGLQVYCCEPFTNMPKDELERMLQLCGASVVKELPSLTHDTG
AHAVVIVQPSAWTEDSNCPDIGQLCKARLVMWDWVLDSLSSYRCRDLDAYLVQNITCVPD
SSEPQDSND
NT seq
5430 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgccgctcgaattcaagaagtacaaagtgtccttcatgctatgcagaaa
atcttagagtgtccaatctgtttggaactgatcaaagaacctgtttccacaaaatgtgac
cacatattttgcaaattttgtatgctgaaacttcttaaccagaagaaagggccttcacaa
tgtcctttgtgtaagaatgagataaccaaaaggagcctacaaggaagcacaaggtttagt
cagcttgttgaagagctgctgaaaatcatggctgcttttgagcttgacacgggaatgcag
gttacaaatggttttagtttttcaaaaaagaaaaataattcttgtgagcgtttgaatgag
gaggagtctatcatccagagcgtgggctaccggaaccgtgtcagaagacttccccaggtc
gaacctggaaatgccaccttgaaggacagcctcagtgtccaggtgtctaaccttggcatc
gtgagatcagtgaagaaaaacaggcagacccaacctcgaaagaaatctgtctacattgaa
ctagactctgactcttctgaagagacagtaactaagccaggtgattgcagtgtgagagac
cgggaattgttacagaccgcccctcaagaagccggagatgaaggcaaggtgcgctctgca
ggagaggctgcttgtgagttttctgagggcataagaaacattgaacatcatcaatgcagt
gatgatttgaaccctactgagaatcatgcaactgaaaggcatccagaaaaatgtcagagt
atttctgtttcaaacgtgcgtgtggagccatgtggcacagatgctcatgccagctcatta
cagcctgagaccagcagtttattgctcattgaagacagaatgaatgcagaaaaggctgaa
ttctgtaataaaagcaaacagcctggcatagcagtgagccagcagagcagatgggcggca
agtaaagaaacatgtaacgacaggcaggttcccagcactggggaaaaggtgggtccaaat
gctgactccctcagtgatagaaagaagtggactcacccgcaaagtctgtgccctgagaat
tctggacctgccaccgatgtttcttggataacactaaatagcagcattcagaaagttaat
gagtggttttccagaactggtgaaatgttaacttctgacagcgcatctgctgggaggcac
gagtcaaatgctgaagcagctgttgtgttggaagtttcaaatgaagtggatgggggtttc
agttcttcaaggaaaacagacttagcagcccccgacccccatcatactttaatgtgtaaa
agtggaagagacttctccaaaccagtagagaataatatcaatgataaaatatttgggaaa
tcctatcagagaaagggaagccgccctcacctgaaccatgtgactgaaattataggcaca
tttattacagagccacagataacacaagagcagcccttcacaaataaattaaaacgtaaa
agacgtacatcccttcagcctgaggacttcatcaagaaagcagattcagcaggtgttcag
aggactcccgacaacacaaatcagggagctggcccaatggagccacatgagcaagcagtg
agtactaccagtaactgtcaggagaacacaatagaaggtagtaatctccagaaagagaga
aacgcctgtccaacggaatcattgagaaaggagcctgcttccacagcaggagccaaatct
aaaagcaacagtgtaagtgatttggaggtagaattaaatgtccgcagttcaaaagcacct
aagaaaaataggctgaggaagaagtcttctaccaggtgtgttcttccacttgaaccaatc
agtagaaatccaagcccacctacttgtgctgaacttgagatcgatagttgtggtagcact
gaagaaacaaagaaaaacagttccaaccaacagccagccaggcaccttagagagcctcaa
ctcatcgaagacactgaacctgcagcggatgccaagaagaacgagccaaatgaacacata
aggaagagacgtgccagcgatgctttcccagaagagaaattaatgaacaaagctggttta
ttaactagctgttcaagtcctcgaaaatctcaagggcctgtcaatcccaaccctcagaaa
acaggaacagagcaagttgaaacacgccaaatacctgacagtgccaaagaactcagggat
caggtcctgagaggagagcccagtggcaaaaccactgaccgatctgaggagagcaccagc
gtgtccttggtacctgacactgactacgacactcagaacagtgtctccgtcctggaagct
aacactgtcagatatgcaagaacaggatccgctcagtgtatgactcagtttgtagcaagc
gagaaccccaaagaactcgtccatggctctaacaatgctgggagtggcacagagtgtctc
aagccccccttgagacacgagcttaaccacagtcaggagaaagtagaaatggaagacagt
gaacttgatactcagtatttgcagaatacatttcaagtttcaaagcgtcagtcatttgct
ttattttcaaaacctagaagtccccaaaaggactgtgcgagtccaaaggtgacagctaaa
ggtaaacaaaaagaacgtcagggacaggaagagtttgaaatcagtcacgtacaggcagtt
gcagccacggtgggcttacctgtgccctgtcaggaaggtaagctagctgctgatacaatg
tgtgatagaggttctaggctttgcccatcatctcattacagaagcggggagaatggactc
agcgccacaggtaaatcgggaatttcacaaaactcacattttaaacaatcagtttctccc
accaggtcatctataaaaattgacaatagaaaacctctgacagagggacgatttgagaaa
catacatcatcaactgaaaaggcggtgggaaatgagaacattcttcagagtacagtgcac
acaattagcctgaataacagaggaaatgcttgtcaagaagccagctcaggcagtattcat
gaagtatgttccactggtgactccttcccgggacagctaggtagaaacagagggcctaag
gtaaacaccgtgcttctattagatagtacgcagcctggtgtctgtcagcaaagtgttcct
gtaagtgataagtatcttgaaataaaaaagcaggagggtgaggctgtctgtgcagacttt
tctccgtgtctattctcagaccatcttgagcaatctatgagaagtggtaaggtttttcag
gtttgctctgagacacctgatgacctgctagatgatgttgaaatacagggacatactagc
tttggtgaaggtgacgtaatggagagatctgctgtctttaacggaagcatcctaagaaga
gagtccagtaggagccctagtcctgtaacccatgcatcgaagtctcggagtctccccaga
gcatctaggaaactagaatcctcagaagagagcgactccactgaggatgaagatctcccc
tgcttccaacacttactgagcagaataagcaacacacctgaactgaacagatgcagcagt
gctgtgacacagcctatgccggagaaagcggaggggacccaagcaccatggaagggtagc
atcagtgactgcaataatgaggtgattgtgatagaggcatctcaggagcatcagctgagt
gaggatccaagatgctctggcagcatgttctcttcacagcacagtgctgcccaagggtca
actgcaattgcaaactcccaggatcccaattttaatccaccttccaaaccgaggagtcac
cagtctgggaatgaggaagctttcctaagtgacaaggaattgatttcagataacgaggaa
atggcaacttgcctagaagaggataatgaccaagaagaggatagtatagtcccagactca
gaggcgtccggatacgagagtgaaacaaacctttctgaagactgctcgcagggagatatt
ttaaccactcagcagcgagcgaccatgaagtataacctgataaagctgcagcaggaaatg
gctcacctggaagctgtgctggagcagcgtgggaaccagccttctggccactccccttcc
ctcctagcagacccttgtgccctggaagacctgccagatctggaaccaaacatgtcagga
gcagcagttttaacttcaaagaacattaatgagaatcctgtaagccaaaatctgaagagc
gcttgtgatgacaaattccaaccacaacatcgggagggtcccaccggtggagatgacgag
tcagggatgggaaggccttccccttttcaatctctgttggcaggcagtaggggttctgca
catggccgctctaggtgtcttcaaaagagaaggtccccctctcaggaggagctcctccag
cctgctggatcagagacatcatctgagccacacaattccacagggcggtcttgcctgcca
aggcaagatctagaaggaaccccatacctggaatctggaatcagccttttctctagtaga
gaccccgagtctgagtcccctaaagagccagcccacattggcaccacaccagcttcaacc
tctgcactgaaaatatcccaaggtcaagttgctgagtctttcaggagtgcagctgctgct
ggtgctgataaagcagtggcaggaattgtgagcaagataaagccggaattgacatcttca
gaagaaagagcggatagagacatagccatggtggtgtcaggcttgacccccaacgaagta
atgattgtgcgaaagtttgctgaaaaataccgcctcacgttaactgacgctatcactgag
gagactacacatgtaattataaaaacagatgctgagtttgtgtgtgagcggacactgaaa
tattttctgggcattgcaggaggaaagtggatagttagctattcgtgggtggtccggtct
atccaagaaagaaaacttctgaatgtgcatgaatttgaagtcaaaggagatgttgtgact
ggaagaaatcaccaaggtccaaggcgatccagagaatcccgggaaaagctcttcaagggc
ctacaggtctattgttgtgagcccttcaccaacatgcccaaagatgagctggagaggatg
ctgcagctgtgtggggcttccgtggtgaaggagcttccatcgctcacccatgacacaggt
gctcatgcagttgtgatcgtgcagccaagcgcctggacagaagacagcaactgcccggat
attgggcagctgtgcaaggcacgtctagtgatgtgggactgggtgttggacagtctatcc
agctaccggtgtcgggatctggatgcctacctggtacagaatatcacctgtgtccctgac
agtagtgagccacaagactccaatgattaa
DBGET
integrated database retrieval system
