Macaca mulatta (rhesus monkey): 721821
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Entry
721821 CDS
T01028
Symbol
MAP2K2
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2 isoform X1
KO
K04369
mitogen-activated protein kinase kinase 2 [EC:
2.7.12.2
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01521
EGFR tyrosine kinase inhibitor resistance
mcc01522
Endocrine resistance
mcc04010
MAPK signaling pathway
mcc04012
ErbB signaling pathway
mcc04014
Ras signaling pathway
mcc04015
Rap1 signaling pathway
mcc04022
cGMP-PKG signaling pathway
mcc04024
cAMP signaling pathway
mcc04066
HIF-1 signaling pathway
mcc04068
FoxO signaling pathway
mcc04071
Sphingolipid signaling pathway
mcc04072
Phospholipase D signaling pathway
mcc04140
Autophagy - animal
mcc04148
Efferocytosis
mcc04150
mTOR signaling pathway
mcc04151
PI3K-Akt signaling pathway
mcc04210
Apoptosis
mcc04218
Cellular senescence
mcc04270
Vascular smooth muscle contraction
mcc04370
VEGF signaling pathway
mcc04371
Apelin signaling pathway
mcc04540
Gap junction
mcc04550
Signaling pathways regulating pluripotency of stem cells
mcc04613
Neutrophil extracellular trap formation
mcc04620
Toll-like receptor signaling pathway
mcc04650
Natural killer cell mediated cytotoxicity
mcc04660
T cell receptor signaling pathway
mcc04662
B cell receptor signaling pathway
mcc04664
Fc epsilon RI signaling pathway
mcc04720
Long-term potentiation
mcc04722
Neurotrophin signaling pathway
mcc04730
Long-term depression
mcc04810
Regulation of actin cytoskeleton
mcc04910
Insulin signaling pathway
mcc04912
GnRH signaling pathway
mcc04915
Estrogen signaling pathway
mcc04916
Melanogenesis
mcc04917
Prolactin signaling pathway
mcc04919
Thyroid hormone signaling pathway
mcc04921
Oxytocin signaling pathway
mcc04926
Relaxin signaling pathway
mcc04929
GnRH secretion
mcc04934
Cushing syndrome
mcc04935
Growth hormone synthesis, secretion and action
mcc05010
Alzheimer disease
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05132
Salmonella infection
mcc05135
Yersinia infection
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05163
Human cytomegalovirus infection
mcc05164
Influenza A
mcc05165
Human papillomavirus infection
mcc05166
Human T-cell leukemia virus 1 infection
mcc05167
Kaposi sarcoma-associated herpesvirus infection
mcc05170
Human immunodeficiency virus 1 infection
mcc05200
Pathways in cancer
mcc05205
Proteoglycans in cancer
mcc05206
MicroRNAs in cancer
mcc05207
Chemical carcinogenesis - receptor activation
mcc05208
Chemical carcinogenesis - reactive oxygen species
mcc05210
Colorectal cancer
mcc05211
Renal cell carcinoma
mcc05213
Endometrial cancer
mcc05214
Glioma
mcc05215
Prostate cancer
mcc05216
Thyroid cancer
mcc05218
Melanoma
mcc05219
Bladder cancer
mcc05220
Chronic myeloid leukemia
mcc05221
Acute myeloid leukemia
mcc05223
Non-small cell lung cancer
mcc05224
Breast cancer
mcc05225
Hepatocellular carcinoma
mcc05226
Gastric cancer
mcc05230
Central carbon metabolism in cancer
mcc05231
Choline metabolism in cancer
mcc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
721821 (MAP2K2)
04012 ErbB signaling pathway
721821 (MAP2K2)
04014 Ras signaling pathway
721821 (MAP2K2)
04015 Rap1 signaling pathway
721821 (MAP2K2)
04370 VEGF signaling pathway
721821 (MAP2K2)
04371 Apelin signaling pathway
721821 (MAP2K2)
04066 HIF-1 signaling pathway
721821 (MAP2K2)
04068 FoxO signaling pathway
721821 (MAP2K2)
04072 Phospholipase D signaling pathway
721821 (MAP2K2)
04071 Sphingolipid signaling pathway
721821 (MAP2K2)
04024 cAMP signaling pathway
721821 (MAP2K2)
04022 cGMP-PKG signaling pathway
721821 (MAP2K2)
04151 PI3K-Akt signaling pathway
721821 (MAP2K2)
04150 mTOR signaling pathway
721821 (MAP2K2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
721821 (MAP2K2)
04148 Efferocytosis
721821 (MAP2K2)
09143 Cell growth and death
04210 Apoptosis
721821 (MAP2K2)
04218 Cellular senescence
721821 (MAP2K2)
09144 Cellular community - eukaryotes
04540 Gap junction
721821 (MAP2K2)
04550 Signaling pathways regulating pluripotency of stem cells
721821 (MAP2K2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
721821 (MAP2K2)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
721821 (MAP2K2)
04620 Toll-like receptor signaling pathway
721821 (MAP2K2)
04650 Natural killer cell mediated cytotoxicity
721821 (MAP2K2)
04660 T cell receptor signaling pathway
721821 (MAP2K2)
04662 B cell receptor signaling pathway
721821 (MAP2K2)
04664 Fc epsilon RI signaling pathway
721821 (MAP2K2)
09152 Endocrine system
04910 Insulin signaling pathway
721821 (MAP2K2)
04929 GnRH secretion
721821 (MAP2K2)
04912 GnRH signaling pathway
721821 (MAP2K2)
04915 Estrogen signaling pathway
721821 (MAP2K2)
04917 Prolactin signaling pathway
721821 (MAP2K2)
04921 Oxytocin signaling pathway
721821 (MAP2K2)
04926 Relaxin signaling pathway
721821 (MAP2K2)
04935 Growth hormone synthesis, secretion and action
721821 (MAP2K2)
04919 Thyroid hormone signaling pathway
721821 (MAP2K2)
04916 Melanogenesis
721821 (MAP2K2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
721821 (MAP2K2)
09156 Nervous system
04720 Long-term potentiation
721821 (MAP2K2)
04730 Long-term depression
721821 (MAP2K2)
04722 Neurotrophin signaling pathway
721821 (MAP2K2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
721821 (MAP2K2)
05206 MicroRNAs in cancer
721821 (MAP2K2)
05205 Proteoglycans in cancer
721821 (MAP2K2)
05207 Chemical carcinogenesis - receptor activation
721821 (MAP2K2)
05208 Chemical carcinogenesis - reactive oxygen species
721821 (MAP2K2)
05230 Central carbon metabolism in cancer
721821 (MAP2K2)
05231 Choline metabolism in cancer
721821 (MAP2K2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
721821 (MAP2K2)
09162 Cancer: specific types
05210 Colorectal cancer
721821 (MAP2K2)
05225 Hepatocellular carcinoma
721821 (MAP2K2)
05226 Gastric cancer
721821 (MAP2K2)
05214 Glioma
721821 (MAP2K2)
05216 Thyroid cancer
721821 (MAP2K2)
05221 Acute myeloid leukemia
721821 (MAP2K2)
05220 Chronic myeloid leukemia
721821 (MAP2K2)
05218 Melanoma
721821 (MAP2K2)
05211 Renal cell carcinoma
721821 (MAP2K2)
05219 Bladder cancer
721821 (MAP2K2)
05215 Prostate cancer
721821 (MAP2K2)
05213 Endometrial cancer
721821 (MAP2K2)
05224 Breast cancer
721821 (MAP2K2)
05223 Non-small cell lung cancer
721821 (MAP2K2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
721821 (MAP2K2)
05170 Human immunodeficiency virus 1 infection
721821 (MAP2K2)
05161 Hepatitis B
721821 (MAP2K2)
05160 Hepatitis C
721821 (MAP2K2)
05164 Influenza A
721821 (MAP2K2)
05163 Human cytomegalovirus infection
721821 (MAP2K2)
05167 Kaposi sarcoma-associated herpesvirus infection
721821 (MAP2K2)
05165 Human papillomavirus infection
721821 (MAP2K2)
09171 Infectious disease: bacterial
05132 Salmonella infection
721821 (MAP2K2)
05135 Yersinia infection
721821 (MAP2K2)
09164 Neurodegenerative disease
05010 Alzheimer disease
721821 (MAP2K2)
05022 Pathways of neurodegeneration - multiple diseases
721821 (MAP2K2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
721821 (MAP2K2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
721821 (MAP2K2)
01522 Endocrine resistance
721821 (MAP2K2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
721821 (MAP2K2)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
721821 (MAP2K2)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: STE group
STE7 family
721821 (MAP2K2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Haspin_kinase
Seadorna_VP7
CAMSAP_CC1
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
721821
NCBI-ProteinID:
XP_014977979
Ensembl:
ENSMMUG00000019564
UniProt:
H9EUI5
LinkDB
All DBs
Position
19:complement(3993110..4028780)
Genome browser
AA seq
400 aa
AA seq
DB search
MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
GTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
PGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgctggcccggaggaagccggtgctgccggcgctcaccatcaaccctaccatcgccgag
ggcccgtcccctaccagcgagggcgcctccgaggcaaacctggtggacctgcagaagaag
ctggaggagctggaacttgacgagcagcagaagaagcgtctggaagcctttctcacccag
aaagccaaggtcggcgaactcaaagacgatgacttcgaaaggatctcagagctgggcgcg
ggcaacggcggggtggtcaccaaagtccagcacagaccctcgggcctcatcatggccagg
aagctgatccaccttgagatcaagccggccatccggaaccagatcatccgcgagctgcag
gtcctgcatgagtgcaactcgccgtacatcgtgggcttctacggggccttctacagcgac
ggggagatcagcatctgcatggagcacatggatggcggctccctggaccaggtgctgaag
gaggccaagaggatccccgaggagatcctggggaaagtcagcattgcggttctccggggc
ttggcgtatctccgagagaagcaccagatcatgcaccgagatgtgaagccctccaacatc
cttgtgaactccagaggggagatcaagctgtgtgacttcggggtgagcggccagctcatc
gactccatggccaactccttcgtgggcacacgctcctacatggctccggagcggttgcag
ggcacacattactcggtgcagtcggacatctggagcatgggcctgtccctggtggagctg
gccatcggaaggtaccccatccccccgcccgacgccaaggagctggaggccatctttggc
cggccggtggtcgacggggaagaaggagagcctcacagcatctcgcctcggccgagaccc
cccgggcgccccatcagcggtcacgggatggatagccggcccgccatggccatcttcgaa
ctgctggactatattgtgaatgagccgcctcctaagctgcccaacggtgtgttcaccccc
gacttccaggagtttgtcaataaatgcctcatcaagaacccagcggagcgggcggacctg
aagatgctcacgaaccacaccttcatcaagcggtccgaggtggaagaagtggattttgcc
gggtggttgtgtaaaaccctgcgactgaaccagcccggcacacccacgcgcaccgccgtg
tga
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