Mycolicibacterium celeriflavum: MCEL_26920
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Entry
MCEL_26920 CDS
T08164
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mcee
Mycolicibacterium celeriflavum
Pathway
mcee00860
Porphyrin metabolism
mcee01100
Metabolic pathways
mcee01110
Biosynthesis of secondary metabolites
mcee01120
Microbial metabolism in diverse environments
mcee01240
Biosynthesis of cofactors
Module
mcee_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mcee_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mcee00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MCEL_26920 (hemD)
Enzymes [BR:
mcee01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MCEL_26920 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MCEL_26920 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY44397
UniProt:
A0A7I7RIP7
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Position
complement(2744673..2746352)
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AA seq
559 aa
AA seq
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MTEMTGQTSGRGRKPKPGRITFVGSGPGDPGLLTTRARTVLGNAALVFTDPDVPEAVLAL
VGSELPPPSGPEPATEAQADGDTAGNDASTIPGGPDIRSAVGDPAEVAKTLIAEARTGVD
VVRLVAGDPLSVDAVISEVSALAKSHLNFEIVPGLPDTTAVPTYAGLPLGSAHTVADVRD
PHVDWAALAAAPGPLILHATATHLADAARTLIEYGLTSTTPVVVTAGGTTCQQRSVETTL
AGLLDKAVLDKPAGIEPAGPLAGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQ
AGEMSDKLEGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWE
KFNEFGLDARAFSGVKIACVGQATADRVRAFGINPELVPAGEQSSLGLLDEFPPYDDVFD
PVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCF
TSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALAEHA
ARLRAEGALPPPRKKSRRR
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
gtgactgagatgacaggccagaccagcgggcgggggcgcaagccgaagccgggccgcatc
acgttcgtcggttcgggtcccggtgaccccggactgctgacgacgcgggcccgcaccgtg
ctcggcaacgccgccctggtgttcaccgatcccgacgtgccggaggcggtgctggccctg
gtgggtagcgagctgccgcccccgtcgggccccgagcccgcgacggaagcgcaggccgac
ggcgacaccgcgggcaacgacgcgtcgaccatcccgggcggacccgacattcgatcggcc
gtcggcgatccggccgaggtggccaagaccctgatcgccgaggcccgcacgggcgtcgac
gtggtgcggctggtcgccggggatccactgtcggtggacgcggtgatcagcgaggtgtcg
gcgctggcgaagtcgcatctgaacttcgagatcgtgccgggcctaccggacaccaccgcg
gtgcccacgtacgcgggcctgccgctgggatcggcccacaccgtggccgacgtccgcgac
ccgcacgtcgactgggcggcgttggccgccgctccggggccgctgatcctgcacgccacg
gcgacccacctggccgatgcggcgcgcacgctgatcgagtacgggctgacctccaccacg
ccggtggtggtgacggccggcggcacgacgtgccagcagcgttcggtcgagacgacgttg
gccgggctgctcgacaaggcggtgctggacaagccggcgggcatcgagccggccggcccg
ttggccggtccgctggtcgtgaccatcggcaagacggtggccaaccgcgccaagctgaac
tggtgggagagccgcgcactgtacggctggaccgtgctggtgccgcgcaccaaggaccag
gccggcgagatgagcgacaagctggagggtcacggggcgcttcccatcgaggtgcccacc
atcgcggtggaaccgccgcgcagccccgcgcagatggagcgtgcggtcaagggtctggtc
gacggccgattccagtgggtggtgttcacctccaccaatgcggtccgcgcggtgtgggag
aagttcaacgagttcggtctcgacgcgcgggccttctcgggggtgaagatcgcctgcgtc
ggccaggccaccgccgaccgggtgcgggcgttcggcatcaaccccgaactggtgcccgcc
ggtgagcagtcgtcgctcggcttgctcgacgaattcccgccgtatgacgacgttttcgat
ccggttaaccgcgtgctgctgccgcgtgccgacatcgccaccgagacgctggccgagggc
ctgcgcgaacgtggttgggagatcgaggatgtcacggcgtaccgcacggttcgcgcggca
ccgccacccgcgcacacccgcgaaatgatcaagaccggtggcttcgacgcggtctgcttc
acctcgagctcgacggttcgcaacctggtcggcatcgcgggcaaaccgcacgcgcggacc
atcgtcgcgtgcatcgggcccaaaaccgccgagaccgcagccgaattcggcctgcgggtg
gatgtgcagcccgaagtcgccgccgtcggcccgctggtggaggcgctcgccgaacacgcc
gcccggttgcgcgccgagggtgcactgccgccgccgcgtaagaagagccggcgtcgctga
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