Micromonospora chalcea: PVK74_27845
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Entry
PVK74_27845 CDS
T08919
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mchl
Micromonospora chalcea
Pathway
mchl00290
Valine, leucine and isoleucine biosynthesis
mchl00660
C5-Branched dibasic acid metabolism
mchl01100
Metabolic pathways
mchl01110
Biosynthesis of secondary metabolites
mchl01210
2-Oxocarboxylic acid metabolism
mchl01230
Biosynthesis of amino acids
Module
mchl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mchl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PVK74_27845 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PVK74_27845 (leuC)
Enzymes [BR:
mchl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PVK74_27845 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
PVK74_27845 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
WDP99620
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All DBs
Position
6140832..6142274
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AA seq
480 aa
AA seq
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MVGVTQPRTLAEKVWDAHVVRSADGEPDLLFIDLHLLHEVTSPQAFDGLRLAGRGVRRTD
LTIATEDHNTPTGYDDPAFRLRRGDLLTIADPTSRTQIETLRRNCAEFGVRLHALGDENQ
GIVHVIGPQLGLTQPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLPQARPKT
MAVNVVGELAPGVTAKDLVLALIAQVGTGGGRGHIVEYRGEAIRDLSMEGRMTIANMSIE
WGAKAGMIAPDETTFAYLKGRPNAPQGDAWDAALEYWRTLPTDDGATFDTEVTLDASRIT
PFVTWGTNPGQGVPLGATVPAPEDFVTEPERVAARRALEYMDLTPGTPMRDLAVDVVFVG
SCTNGRLEDLRAAADVLRGHRVADGVRMLVVPGSAAVREAAEIEGLDKVFTEAGAEWRFA
GCSMCLGMNPDTLKPGERSASTSNRNFEGRQGRGGRTHLVSPPVAAATAVVGRLAAPADL
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atggtgggagtcactcaaccgaggaccctggccgagaaggtctgggacgcacacgtggtc
cgctccgccgacggcgagccggacctgctcttcatcgacctgcacctgctgcacgaggtg
accagcccgcaggcgttcgacgggctgcgtctggccgggcgcggggtccgccgtaccgac
ctgacgatcgcgacggaggaccacaacaccccgaccgggtacgacgacccggcgttccgc
ctccggcgcggcgacctgctcacgatcgcggaccccacctcccgcacccagatcgagacg
ctgcgtcgcaactgtgccgagttcggcgtccgcctgcacgcgctgggcgacgagaaccag
ggcatcgtgcatgtcatcggcccgcagctcggcctcacccagcccggcatgacgatcgtg
tgcggcgactcgcacaccgccacccacggcgcgttcggcgcgctcgcgttcggcatcggc
accagtgaggtcgaacacgtgctggccacgcagacgctgccgcaggcccggccgaagacc
atggccgtgaacgtggtcggcgagctggcgcccggcgtcaccgccaaggacctggtgctc
gcgctgatcgcgcaggtcggcaccggcggcggtcgcggtcacatcgtcgagtaccggggc
gaggcgatccgcgacctctccatggaggggcggatgaccatcgccaacatgtccatcgag
tggggcgccaaggccggcatgatcgcgccggacgagaccacgttcgcgtacctgaagggg
cggcccaacgcgccccagggcgacgcctgggacgcggcgctggagtactggcggacgctg
cccaccgacgacggcgcgacgttcgacaccgaggtcacgctcgacgcgagccggatcacg
ccgttcgtcacctggggcaccaaccccgggcagggtgtgccgctgggcgcgacggtgccg
gccccggaggacttcgtcaccgagccggagcgggtcgccgcccggcgcgcgctggagtac
atggacctcaccccgggcacgccgatgcgtgacctggccgtggacgtggtcttcgtcggc
tcctgcaccaacggccgcctggaggacctgcgtgccgccgccgacgtgctgcgcgggcac
cgcgtcgccgacggcgtacgcatgctcgtggtccccggctcggccgcggtccgcgaggcg
gccgagatcgaagggctggacaaggtcttcaccgaggccggcgccgagtggcgtttcgcc
ggctgctccatgtgcctgggcatgaacccggacacgctgaagccgggtgagcgttccgcc
tcgacctccaaccgcaacttcgagggccgccagggccggggcgggcgtacccacctggtg
tccccgccggtcgccgccgccaccgccgtggtcggccggctggccgcccccgccgacctg
tag
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