Mastomys coucha (southern multimammate mouse): 116102479
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Entry
116102479 CDS
T07224
Symbol
Pde8a
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00230
Purine metabolism
mcoc01100
Metabolic pathways
mcoc04927
Cortisol synthesis and secretion
mcoc04934
Cushing syndrome
mcoc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
116102479 (Pde8a)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
116102479 (Pde8a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
116102479 (Pde8a)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
116102479 (Pde8a)
Enzymes [BR:
mcoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
116102479 (Pde8a)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PAS_4
PDE8
PAS_3
PAS_8
Response_reg
UBA_E1_SCCH
DUF5894
Motif
Other DBs
NCBI-GeneID:
116102479
NCBI-ProteinID:
XP_031243031
LinkDB
All DBs
Position
Unknown
AA seq
827 aa
AA seq
DB search
MGCAPSIHVSENRTLNHSDDEDEDVEVPGPAPRSRLRWSTAPGLVEPQPRDSGASKVSVA
DVQFGPMRFHQDQLQVLLVFTKEDNQCNGFHRACEKAGFKCTVTKEVQTVLTCFQDKLHD
IIIIDHRNPRQMDAEALCRSIRSSKFSEHTVIVGVVRRVDKEEVSIMPFLAAGFTRRYIE
NPSVMACYNELLQLAFGEVQSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAFET
TMGYQAGELIGKELAQVPINEKKGDLLDALNSCVTIDKEWQGVYHTQKKNGDNIQQNVKI
IPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQTDSQTDNQAGKHKDRRKHSMDAKAVS
SRASDVSSQRRHSSLARIHSMMIEAPITKVINIINAAQENSPLPVTEALNRVLDILRATE
LYSPQFNAEDDPHATDLVGGLMSDGLRRFSGNEYVLATKNLPPSSNNMPAPISLHDIPPR
IALVMEDEEQWDFDIFELEAATQNRPLIYLGLKTFARFGMCEFLRCSETTLRSWFQIIES
NYHSSNPYHNSTHAADVLHATAYFLSRNKIKETLDRNDEVAALIAAAIHDVDHPGRTNSF
LCNAGNHLAVLYNDTAVLESHHVALAFQLTLENDKCNIFKQMERSDYRTLRQSIIDMVLA
TEMTKHFEHVNKFINSINKPLTAQEKEETGRSLEDIKAMLKTSESRALIKRMMIKCADVS
NPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFITD
MFDAWDALFLSPAFVDLPNLMQHLDDNFKYWKGLDEKKLRCLRPPPE
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccaagcatccacgtttccgaaaaccgaacgttgaaccacagcgacgac
gaggacgaggacgtggaagtcccgggccccgcgccgaggtctagactgcgatggtcgacc
gcacccgggctcgtggagccacagcctcgcgacagcggcgcctcgaaggtatcagtagct
gatgtgcaatttggcccgatgagatttcatcaagatcaacttcaggtacttttagtgttt
accaaagaagataaccagtgtaatggattccacagggcatgtgaaaaagctgggtttaag
tgcacagtcaccaaggaggtgcagactgtccttacctgtttccaggacaaactccatgac
atcatcatcatagaccacagaaatccccgacagatggatgcagaggcactgtgcaggtct
atcagatcatcaaaattctcagaacatacagttattgttggcgtagtacgcagggtggac
aaagaagaggtatctataatgcccttccttgctgctggcttcacacggaggtatatagaa
aaccccagcgtcatggcctgttataatgaactgctccagttggcatttggagaggtgcaa
tcacaactgaaactcagggcttgtaactcagtattcaccgcattagagaaaagtcaagaa
gcaattgaaattacaagtgaagaccacattatacagtatgcaaaccctgcatttgaaaca
acaatgggttatcaggcaggagaactaatagggaaggagttagcacaagtacccataaat
gaaaagaaaggtgatttgctcgatgccttaaattcatgtgtcaccatagacaaggagtgg
caaggagtttaccatacccaaaagaaaaatggagacaacatacaacaaaatgtgaagata
atacctgtcattgggcagggaggaaaaatcagacactatgtgtccattatcagagtgtgc
aatggcaacaataaggttgagaccaccactgagtgtgttcagactgacagtcaaacagat
aatcaggcaggcaaacataaagacaggaggaagcattcgatggatgccaaagctgtttcc
tccagagcaagtgatgtttccagccagagaagacattcctctttggcccggatacattct
atgatgattgaggcacccatcaccaaggtaatcaatattatcaacgctgcccaggaaaac
agtcctctgcctgtaacagaagccttgaaccgtgtgctggatattctgagagccactgag
ttgtattcaccacagtttaatgctgaggacgatcctcacgccaccgacctcgttgggggc
ttaatgtctgatggcttacgaaggttttcaggaaatgagtatgttcttgcaacaaaaaac
cttccgccatcttcaaacaatatgcccgcccccatctcccttcatgatatcccaccacgg
attgccctggtcatggaagatgaagaacaatgggactttgacatttttgagctggaagca
gcaacccaaaataggcctttgatttatctaggtctcaaaacgtttgctcgttttggaatg
tgtgaattcttacggtgctctgagacaacactgagatcgtggtttcagattatcgaatcc
aattaccattcttctaacccctaccacaattccacacatgctgcagatgtgcttcacgcc
actgcatatttcctttccagaaacaaaataaaggaaactttagatcgaaatgacgaggtt
gctgccctcattgctgccgccatccacgatgtggatcaccctgggagaaccaactccttc
ctctgcaatgcaggaaaccatctggccgtgctctacaatgacactgctgtgctagagagc
caccatgtggcgctggccttccagctgacgcttgaaaatgacaaatgcaatatctttaaa
caaatggagaggagtgactaccggacactacgccagagtattattgacatggtcctagcc
acagaaatgacaaagcactttgaacatgtcaacaaatttatcaacagcatcaacaagcct
ttgacagcacaagagaaggaggaaactggcagaagtctggaagacataaaagctatgctc
aagacttcagagagccgggctctcatcaaaagaatgatgattaagtgtgccgatgtgtcc
aatccctgccggcccctagagcactgcatcgagtgggctgcacgcatttcagaggagtat
ttttctcagactgatgaagagaaacagctggacttgcctgtggtgatgccagtgtttgac
agaaacacctgcagcattcccaagtctcagatctcctttattgactacttcattacagac
atgtttgatgcctgggatgcgctgtttctctcgccagcctttgttgacctgcctaacctt
atgcagcacctagatgacaacttcaagtattggaagggactggatgagaagaagctgcgc
tgcctccggccccctccagaatag
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