Mycobacterium cookii: MCOO_39590
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Entry
MCOO_39590 CDS
T07035
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mcoo
Mycobacterium cookii
Pathway
mcoo00860
Porphyrin metabolism
mcoo01100
Metabolic pathways
mcoo01110
Biosynthesis of secondary metabolites
mcoo01120
Microbial metabolism in diverse environments
mcoo01240
Biosynthesis of cofactors
Module
mcoo_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mcoo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mcoo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MCOO_39590 (hemD)
Enzymes [BR:
mcoo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MCOO_39590 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MCOO_39590 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBX47944
UniProt:
A0A7I7L1J8
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All DBs
Position
4241344..4243002
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AA seq
552 aa
AA seq
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MTTRGRKPRPGRIMFVGAGPGDPALLTTRAAAVLANAPLVFIDPDVPEPVLALIGKDLPP
VSGPAPAEPAAPSDNGASEGSAPEDQPTVVSVGPDIRPALGDPAEVAKTLVAEARTGADV
VRLVSGDPLSVDSVITEVNSVARSHLHFEIVPGLAASDAVPTYAGLPLGSSHTVADVRGD
VDWGALAAGPGPLILQATSSHVADAARTLIEYGLADTTPCVVTSSGTTCAQRSLESTLGG
LTDTNLVIGADGAAPSPVVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSDR
LTAHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSLGLLDEFPPYDSIFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLIEALAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgcaagccgcggcccggccgcatcatgttcgtgggggcgggtcct
ggggaccccgcgctgctgacgacgcgggccgctgcggtactggcaaatgcccctctggtg
ttcattgaccccgacgtgcccgagcccgtgctggcgctgatcggcaaggatctgccgcca
gtgtccgggcccgcgccggccgagccggctgcgccgtcggacaacggagccagcgagggg
tccgcacccgaagatcaacccaccgtggtgtcggtgggccccgacatccggcccgcactg
ggcgatcccgccgaggtggccaagacgctggtcgccgaggctcgcaccggagcagacgtg
gtgcggctggtgtccggtgacccgctgtcggtggactcggtgatcaccgaggtgaattcg
gtggctcgcagccacctgcatttcgagatcgtgccgggcctggcggccagcgacgcagtg
ccgacctatgccgggctgccgctcggctcgtcgcacaccgtcgccgacgtccgtggcgac
gtggactggggcgcgttggccgcaggcccgggcccactgatcctgcaggccacgtcctcg
cacgtggccgacgcggcgcgcacgctgatcgaatacgggttggccgacaccactccgtgt
gtggtgacgtcgtccggaaccacctgtgcgcagcgctctctggagtcgacgctgggtggg
ctgaccgataccaacctggtcatcggcgccgacggtgccgccccgtcgccggtggtcgtc
accatcggcaagacggtggccaaccgggccaagctgaactggtgggagagccgcgccctg
tacggctggaccgtgctggtgccgcggaccaaggaccaggccggcgagatgagtgatcgg
ctgaccgcgcacggcgcgctgccgatcgaggtgccgaccattgccgtcgagccgccgcgc
agccccgcgcagatggagcgtgcggtcaagggtctggtcgacggccgctaccagtgggtg
gtgttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcgggctc
gacgcccgcgcattctccggagtgaagatcgcctgcgtcggcgaatcgaccgccgaccgg
gtgcgcgctttcgggatcagccccgagctggtgccttccggtgagcaatcgtcgctgggc
ctgctcgacgaattcccgccctacgacagcattttcgatccggtgaaccgggtgctgcta
ccgcgggccgacatcgccaccgagacgttggccgagggtctgcgcgaacgtggttgggag
atcgaggatgtcaccgcctaccggaccgtgcgggctgccccgccgccggcggccacccgc
gagatgatcaagaccggtggtttcgacgcggtgtgcttcacgtcgagctcgacggtgcgc
aacctggtcggcatcgccggcaagccgcatgcgcgcacgatcgtcgcgtgtatcggcccc
aagaccgccgagacggcagccgaattcggtttgcgcgtcgacgtgcaacccgagaccgcc
gcggtgggcccgctgatcgaagcgctggccgagcacgccgcccggttgcgcgccgagggt
gcgctgccgccgccgcgtaagaagagccgcaggcgatga
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