Mycobacterium cookii: MCOO_49450
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Entry
MCOO_49450 CDS
T07035
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mcoo
Mycobacterium cookii
Pathway
mcoo00290
Valine, leucine and isoleucine biosynthesis
mcoo00660
C5-Branched dibasic acid metabolism
mcoo01100
Metabolic pathways
mcoo01110
Biosynthesis of secondary metabolites
mcoo01210
2-Oxocarboxylic acid metabolism
mcoo01230
Biosynthesis of amino acids
Module
mcoo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mcoo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MCOO_49450 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MCOO_49450 (leuC)
Enzymes [BR:
mcoo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MCOO_49450 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MCOO_49450 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBX48930
UniProt:
A0A7I7L3H3
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All DBs
Position
5272209..5273588
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AA seq
459 aa
AA seq
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MWEDHVVASGGGTEPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVRRPDLTIATEDHNVPT
IDIDKPIADPVSRKQVETLRSNCAEFGVRLYPMGDIEQGIVHVVGPQLGLTQPGMTVVCG
DSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGELPPGVTAKDIILAV
IAKIGTGGGQGHVIEYRGSAIESLSMEARMTVCNMSIEAGARAGMVAPDATTYEFLRGRP
HAPTGAQWDAAQAYWDQLRTDDGAEFDTEVHLDAASLTPFVTWGTNPGQGVPLGAVVPDP
ELMSDDNERQSAEKALAYMDLRPGTPMRDIAVDTVFVGSCTNGRIEDLRAVADILRGRKV
ADGVRMLVVPGSMRVRAVAESEGLGEIFTAAGAEWRQAGCSMCLGMNPDQLAPGERCAAT
SNRNFEGRQGKGGRTHLVSPAVAAATAVRGKLSAPADLN
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
gtgtgggaggaccacgtggtggcctccggcggtggcaccgaacctgacctgatctacatc
gatctgcatctggtgcacgaggtcaccagtccgcaagccttcgacggtctgcgcttggcc
ggccggccggtacgccgccccgacctgacgatcgcgaccgaagaccacaacgtgccaacg
atcgacatcgacaagccgatcgctgatccggtgtcgcgcaaacaagtcgagactctgcgg
agcaactgcgccgaattcggtgtccgtctctatccgatgggcgatatcgaacagggcatc
gtgcatgtggtcggtccgcagttgggtctgacccagccggggatgacggtcgtctgcggc
gacagccacacctcgacgcacggcgcattcggcgcgttggcgatgggcatcgggacgtcg
gaggtcgagcatgtgctcgccacgcagacacttccactgcggccgttcaagaccatggcc
gtcaatgtcgacggcgagttgccgcccggggtgacggccaaggacatcattcttgcggtc
atcgccaagatcgggaccggcggcgggcagggtcacgtcatcgaataccgcggcagcgcc
atcgagtcgctgtcgatggaggcccggatgacggtctgcaacatgagcatcgaggccggc
gcgagggcgggaatggtggcgcccgacgccaccacctacgaattcctgcgcggccgtccg
cacgcgccgaccggcgcgcagtgggatgcggcgcaggcgtactgggatcagctgcgcacc
gacgacggcgccgagttcgacaccgaagtccatctggacgccgcctcgttgaccccgttc
gtgacgtggggcaccaatccgggccagggcgtgccgctgggcgcggtggtaccggacccc
gagctgatgtccgacgacaacgagcggcagtcggccgagaaagcgctggcgtacatggat
cttcggccgggaacgccgatgcgcgacatcgccgtggacacggtgttcgtcggctcgtgc
accaacgggcgcatcgaggatctgcgcgcggtggccgacattctgcggggacggaaggtg
gccgacggcgtacggatgctggttgtgcccggatcgatgcgggtgcgcgcggtggccgaa
agtgaagggctgggcgagatcttcaccgccgcaggcgccgaatggcggcaggccggctgc
tcgatgtgcttggggatgaatcccgatcaactcgcaccgggggagcgctgcgcggcaacg
tcgaaccgcaacttcgaaggacgtcagggcaagggcggccgtacgcatttggtgtcgccg
gccgtcgccgcggccaccgcagtgcgcggaaaactctccgccccggccgacttgaactga
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