Mycolicibacterium crocinum: MI149_04325
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Entry
MI149_04325 CDS
T08227
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mcro
Mycolicibacterium crocinum
Pathway
mcro00860
Porphyrin metabolism
mcro01100
Metabolic pathways
mcro01110
Biosynthesis of secondary metabolites
mcro01120
Microbial metabolism in diverse environments
mcro01240
Biosynthesis of cofactors
Module
mcro_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mcro_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mcro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MI149_04325
Enzymes [BR:
mcro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MI149_04325
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MI149_04325
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Motif
Pfam:
HEM4
TP_methylase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ULN42359
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Position
908111..909772
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AA seq
553 aa
AA seq
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MTGHVSGRGRKAKPGHITFVGSGPGDPNLLTTRARTVLSNAALVFTDPDVPQAVLNVIGT
ELPPAVGPAPAPDGPPAEGHDETAPPVVSVGPDIRPALGDPAEVAKTLVHEAKAGFDVVR
LVAGDPLSIDSVITEVNAVAKAHAEFEIVPGLPATSAVPTYAGLPLGSAHTVADVRGEVD
WAALAAAPGPLILTATASHLPEAARTLIEYGLAESTPCVVTSNGTTCGQRSVETTLHGLT
DRATLACNSDPAGPLTGTLVATIGKTVAHRAKLNWWESRALYGWTVLVPRTKDQAGEMSD
RLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFGEFG
LDARAFSGVKIACVGEQTADRVRAFGVSPELVPAGEQSSLGLLDEFPEYDSIFDPVNRVL
LPRADIATETLAEGLRDRGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTV
RNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAE
GALPPPRKKSRRR
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgactggtcatgtgagcggtcggggacgtaaggcgaagccgggacacatcacgttcgtc
ggctcgggtccaggcgaccccaacctgttgacgacgcgagcccgcaccgtgttgtccaat
gccgcgctggtattcaccgatcccgacgtgcctcaggccgtcctcaacgtgatcggcacc
gagctgccgccggccgtcggcccggcgccggcaccggacggcccacccgccgagggtcac
gacgagaccgccccgccggtcgtctcggtcggcccggacatccgccccgcgctgggcgac
ccggccgaggtggccaagacgctggtccacgaagccaaggccggtttcgatgtggttcgg
ctggtcgctggtgacccgctgtcgatcgattcggtcatcaccgaggtcaatgccgtcgcc
aaggctcacgccgagttcgagatcgtccccggtctgcccgccaccagcgcggtcccgacc
tatgcgggcctgcccctgggctcggcgcataccgtcgccgacgtgcgcggcgaggtcgac
tgggcggcgctggccgccgcgcccggcccgctgatcctcaccgcgaccgcctcgcacctg
ccggaggccgcgcgcaccctgatcgagtacggcctggccgagagcacgccctgcgtggtg
acctccaacggcaccacctgtggtcagcgttcggtcgagaccaccctgcacggcctcacc
gaccgcgcgacgctggcctgcaacagcgatccggccggcccgctgaccggcaccctggtg
gccaccatcggcaagaccgtggcgcaccgcgccaagctgaactggtgggagagccgggcc
ctgtacggctggaccgtgctggtgccccgcaccaaggaccaggccggcgagatgagcgac
cggctggtcggtcacggcgcgctgccgatcgaggtgccgacgatcgccgtcgagcctccg
cgcagcccggcccaaatggaaagggctgtcaagggtttggtggacggccgctaccagtgg
gtggtgttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcggc
ctggacgcccgggcgttctccggtgtgaagatcgcctgcgtgggcgagcagaccgccgac
cgggtccgcgcgttcggcgtgagccccgaactggtgcccgccggtgagcagtcctcgctc
ggtctcctcgacgaattcccggagtacgacagcattttcgacccggtcaaccgggtgttg
ctgccgcgcgccgacatcgccaccgagacgctggccgaaggtctgcgcgaccgtggctgg
gagatcgaagacgtcaccgcctaccggaccgtccgcgcggcaccgccgccggccgagacc
cgcgagatgatcaagaccggcgggttcgacgcggtgtgcttcacctcgagctccacggtg
cgcaatctggtcggcatcgccggcaagccgcacgcccgcaccatcgtggcgtgcatcggg
ccgaagaccgctgagacggccgcggagttcgggctgcgggtcgacgtgcagccggagacc
gccgcggtcggaccgctggtcgacgcgctcgccgagcatgccgcccggctgcgcgccgag
ggcgcgctgccgccgccgcgcaagaagagccgacgccgctaa
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