KEGG   Monodelphis domestica (gray short-tailed opossum): 100026324
Entry
100026324         CDS       T01031                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01522  Endocrine resistance
mdo04010  MAPK signaling pathway
mdo04015  Rap1 signaling pathway
mdo04068  FoxO signaling pathway
mdo04071  Sphingolipid signaling pathway
mdo04114  Oocyte meiosis
mdo04148  Efferocytosis
mdo04218  Cellular senescence
mdo04261  Adrenergic signaling in cardiomyocytes
mdo04370  VEGF signaling pathway
mdo04380  Osteoclast differentiation
mdo04550  Signaling pathways regulating pluripotency of stem cells
mdo04611  Platelet activation
mdo04613  Neutrophil extracellular trap formation
mdo04620  Toll-like receptor signaling pathway
mdo04621  NOD-like receptor signaling pathway
mdo04622  RIG-I-like receptor signaling pathway
mdo04625  C-type lectin receptor signaling pathway
mdo04657  IL-17 signaling pathway
mdo04658  Th1 and Th2 cell differentiation
mdo04659  Th17 cell differentiation
mdo04660  T cell receptor signaling pathway
mdo04664  Fc epsilon RI signaling pathway
mdo04668  TNF signaling pathway
mdo04670  Leukocyte transendothelial migration
mdo04714  Thermogenesis
mdo04722  Neurotrophin signaling pathway
mdo04723  Retrograde endocannabinoid signaling
mdo04728  Dopaminergic synapse
mdo04750  Inflammatory mediator regulation of TRP channels
mdo04912  GnRH signaling pathway
mdo04914  Progesterone-mediated oocyte maturation
mdo04917  Prolactin signaling pathway
mdo04926  Relaxin signaling pathway
mdo04932  Non-alcoholic fatty liver disease
mdo04933  AGE-RAGE signaling pathway in diabetic complications
mdo04935  Growth hormone synthesis, secretion and action
mdo04936  Alcoholic liver disease
mdo05014  Amyotrophic lateral sclerosis
mdo05020  Prion disease
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05132  Salmonella infection
mdo05133  Pertussis
mdo05135  Yersinia infection
mdo05140  Leishmaniasis
mdo05142  Chagas disease
mdo05145  Toxoplasmosis
mdo05152  Tuberculosis
mdo05161  Hepatitis B
mdo05163  Human cytomegalovirus infection
mdo05167  Kaposi sarcoma-associated herpesvirus infection
mdo05169  Epstein-Barr virus infection
mdo05170  Human immunodeficiency virus 1 infection
mdo05171  Coronavirus disease - COVID-19
mdo05205  Proteoglycans in cancer
mdo05208  Chemical carcinogenesis - reactive oxygen species
mdo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mdo05415  Diabetic cardiomyopathy
mdo05417  Lipid and atherosclerosis
mdo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100026324 (MAPK14)
   04015 Rap1 signaling pathway
    100026324 (MAPK14)
   04370 VEGF signaling pathway
    100026324 (MAPK14)
   04668 TNF signaling pathway
    100026324 (MAPK14)
   04068 FoxO signaling pathway
    100026324 (MAPK14)
   04071 Sphingolipid signaling pathway
    100026324 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100026324 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100026324 (MAPK14)
   04218 Cellular senescence
    100026324 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100026324 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100026324 (MAPK14)
   04613 Neutrophil extracellular trap formation
    100026324 (MAPK14)
   04620 Toll-like receptor signaling pathway
    100026324 (MAPK14)
   04621 NOD-like receptor signaling pathway
    100026324 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    100026324 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    100026324 (MAPK14)
   04660 T cell receptor signaling pathway
    100026324 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    100026324 (MAPK14)
   04659 Th17 cell differentiation
    100026324 (MAPK14)
   04657 IL-17 signaling pathway
    100026324 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    100026324 (MAPK14)
   04670 Leukocyte transendothelial migration
    100026324 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100026324 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    100026324 (MAPK14)
   04917 Prolactin signaling pathway
    100026324 (MAPK14)
   04926 Relaxin signaling pathway
    100026324 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    100026324 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100026324 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    100026324 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    100026324 (MAPK14)
   04722 Neurotrophin signaling pathway
    100026324 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100026324 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100026324 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    100026324 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100026324 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    100026324 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100026324 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100026324 (MAPK14)
   05161 Hepatitis B
    100026324 (MAPK14)
   05171 Coronavirus disease - COVID-19
    100026324 (MAPK14)
   05163 Human cytomegalovirus infection
    100026324 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100026324 (MAPK14)
   05169 Epstein-Barr virus infection
    100026324 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100026324 (MAPK14)
   05135 Yersinia infection
    100026324 (MAPK14)
   05133 Pertussis
    100026324 (MAPK14)
   05152 Tuberculosis
    100026324 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100026324 (MAPK14)
   05140 Leishmaniasis
    100026324 (MAPK14)
   05142 Chagas disease
    100026324 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100026324 (MAPK14)
   05020 Prion disease
    100026324 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    100026324 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100026324 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    100026324 (MAPK14)
   05415 Diabetic cardiomyopathy
    100026324 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100026324 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    100026324 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100026324 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100026324 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdo01001]
    100026324 (MAPK14)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100026324 (MAPK14)
Protein kinases [BR:mdo01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100026324 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 100026324
NCBI-ProteinID: XP_001369941
Ensembl: ENSMODG00000013704
UniProt: A0A5F8GJU8
LinkDB
Position
2:275178103..275271973
AA seq 360 aa
MSQERPKFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDKKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHGYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcctaagttctaccggcaggagctgaacaagaccatctgggaggtg
cccgagcgctaccagaacctgtccccagtaggttcgggcgcctatgggtccgtatgtgct
gcttttgacaaaaaaacagggttacgtgtggcagtgaagaagttatccagaccatttcag
tccatcatccatgcaaaaaggacttacagggaattgcgattacttaagcatatgaaacat
gaaaatgtgattggcctgttagatgttttcacacctgcaaagtctctggaggaattcaat
gatgtgtatctggtgacacatctcatgggggcagatctgaacaatattgtgaaatgccaa
aagctcaccgatgaccatgtacagttccttatctaccagattctccgaggcttaaagtat
attcattcagctgacattatacacagagacctgaaacctagtaacttagctgtgaatgaa
gactgtgagcttaagatcctagattttggactggcccggcacacagatgatgaaatgaca
ggttatgtagccaccaggtggtatagggctcctgagatcatgctgaactggatgcattac
aaccaaacagttgatatttggtcagtgggatgcataatggcagaactgttgactggaagg
acactgtttcctggtaccgaccatattaaccagcttcagcagatcatgcgcctgacgggg
acaccccctgcctatctcattaacaggatgcccagtcatgaggcaagaaattatattcaa
tctttgacccagatgccgaagatgaactttgcaaatgtgtttattggtgccaatccatta
gctgttgacctgctggagaagatgcttgtattggactcggataagagaattacagcagct
caagcccttgcccatggctactttgcccagtaccacgatcctgatgatgaaccagttgca
gacccctatgaccagtcctttgaaagcagggatctcctgatagatgaatggaaaagcctg
acctatgatgaagttataagttttgtgccgccaccacttgaccaagaagagatggagtcc
tga

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