Monodelphis domestica (gray short-tailed opossum): 100027373
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Entry
100027373 CDS
T01031
Symbol
AKT3
Name
(RefSeq) AKT serine/threonine kinase 3
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo01522
Endocrine resistance
mdo01524
Platinum drug resistance
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04014
Ras signaling pathway
mdo04015
Rap1 signaling pathway
mdo04022
cGMP-PKG signaling pathway
mdo04024
cAMP signaling pathway
mdo04062
Chemokine signaling pathway
mdo04066
HIF-1 signaling pathway
mdo04068
FoxO signaling pathway
mdo04071
Sphingolipid signaling pathway
mdo04072
Phospholipase D signaling pathway
mdo04140
Autophagy - animal
mdo04150
mTOR signaling pathway
mdo04151
PI3K-Akt signaling pathway
mdo04152
AMPK signaling pathway
mdo04210
Apoptosis
mdo04211
Longevity regulating pathway
mdo04213
Longevity regulating pathway - multiple species
mdo04218
Cellular senescence
mdo04261
Adrenergic signaling in cardiomyocytes
mdo04370
VEGF signaling pathway
mdo04371
Apelin signaling pathway
mdo04380
Osteoclast differentiation
mdo04510
Focal adhesion
mdo04550
Signaling pathways regulating pluripotency of stem cells
mdo04611
Platelet activation
mdo04613
Neutrophil extracellular trap formation
mdo04620
Toll-like receptor signaling pathway
mdo04625
C-type lectin receptor signaling pathway
mdo04630
JAK-STAT signaling pathway
mdo04660
T cell receptor signaling pathway
mdo04662
B cell receptor signaling pathway
mdo04664
Fc epsilon RI signaling pathway
mdo04666
Fc gamma R-mediated phagocytosis
mdo04668
TNF signaling pathway
mdo04722
Neurotrophin signaling pathway
mdo04725
Cholinergic synapse
mdo04728
Dopaminergic synapse
mdo04810
Regulation of actin cytoskeleton
mdo04910
Insulin signaling pathway
mdo04914
Progesterone-mediated oocyte maturation
mdo04915
Estrogen signaling pathway
mdo04917
Prolactin signaling pathway
mdo04919
Thyroid hormone signaling pathway
mdo04920
Adipocytokine signaling pathway
mdo04922
Glucagon signaling pathway
mdo04923
Regulation of lipolysis in adipocytes
mdo04926
Relaxin signaling pathway
mdo04929
GnRH secretion
mdo04931
Insulin resistance
mdo04932
Non-alcoholic fatty liver disease
mdo04933
AGE-RAGE signaling pathway in diabetic complications
mdo04935
Growth hormone synthesis, secretion and action
mdo04936
Alcoholic liver disease
mdo04973
Carbohydrate digestion and absorption
mdo05010
Alzheimer disease
mdo05017
Spinocerebellar ataxia
mdo05132
Salmonella infection
mdo05135
Yersinia infection
mdo05142
Chagas disease
mdo05145
Toxoplasmosis
mdo05152
Tuberculosis
mdo05160
Hepatitis C
mdo05161
Hepatitis B
mdo05162
Measles
mdo05163
Human cytomegalovirus infection
mdo05164
Influenza A
mdo05165
Human papillomavirus infection
mdo05166
Human T-cell leukemia virus 1 infection
mdo05167
Kaposi sarcoma-associated herpesvirus infection
mdo05168
Herpes simplex virus 1 infection
mdo05169
Epstein-Barr virus infection
mdo05170
Human immunodeficiency virus 1 infection
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05207
Chemical carcinogenesis - receptor activation
mdo05208
Chemical carcinogenesis - reactive oxygen species
mdo05210
Colorectal cancer
mdo05211
Renal cell carcinoma
mdo05212
Pancreatic cancer
mdo05213
Endometrial cancer
mdo05214
Glioma
mdo05215
Prostate cancer
mdo05218
Melanoma
mdo05220
Chronic myeloid leukemia
mdo05221
Acute myeloid leukemia
mdo05222
Small cell lung cancer
mdo05223
Non-small cell lung cancer
mdo05224
Breast cancer
mdo05225
Hepatocellular carcinoma
mdo05226
Gastric cancer
mdo05230
Central carbon metabolism in cancer
mdo05231
Choline metabolism in cancer
mdo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mdo05415
Diabetic cardiomyopathy
mdo05417
Lipid and atherosclerosis
mdo05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100027373 (AKT3)
04012 ErbB signaling pathway
100027373 (AKT3)
04014 Ras signaling pathway
100027373 (AKT3)
04015 Rap1 signaling pathway
100027373 (AKT3)
04370 VEGF signaling pathway
100027373 (AKT3)
04371 Apelin signaling pathway
100027373 (AKT3)
04630 JAK-STAT signaling pathway
100027373 (AKT3)
04668 TNF signaling pathway
100027373 (AKT3)
04066 HIF-1 signaling pathway
100027373 (AKT3)
04068 FoxO signaling pathway
100027373 (AKT3)
04072 Phospholipase D signaling pathway
100027373 (AKT3)
04071 Sphingolipid signaling pathway
100027373 (AKT3)
04024 cAMP signaling pathway
100027373 (AKT3)
04022 cGMP-PKG signaling pathway
100027373 (AKT3)
04151 PI3K-Akt signaling pathway
100027373 (AKT3)
04152 AMPK signaling pathway
100027373 (AKT3)
04150 mTOR signaling pathway
100027373 (AKT3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100027373 (AKT3)
09143 Cell growth and death
04210 Apoptosis
100027373 (AKT3)
04218 Cellular senescence
100027373 (AKT3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100027373 (AKT3)
04550 Signaling pathways regulating pluripotency of stem cells
100027373 (AKT3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100027373 (AKT3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100027373 (AKT3)
04613 Neutrophil extracellular trap formation
100027373 (AKT3)
04620 Toll-like receptor signaling pathway
100027373 (AKT3)
04625 C-type lectin receptor signaling pathway
100027373 (AKT3)
04660 T cell receptor signaling pathway
100027373 (AKT3)
04662 B cell receptor signaling pathway
100027373 (AKT3)
04664 Fc epsilon RI signaling pathway
100027373 (AKT3)
04666 Fc gamma R-mediated phagocytosis
100027373 (AKT3)
04062 Chemokine signaling pathway
100027373 (AKT3)
09152 Endocrine system
04910 Insulin signaling pathway
100027373 (AKT3)
04922 Glucagon signaling pathway
100027373 (AKT3)
04923 Regulation of lipolysis in adipocytes
100027373 (AKT3)
04920 Adipocytokine signaling pathway
100027373 (AKT3)
04929 GnRH secretion
100027373 (AKT3)
04915 Estrogen signaling pathway
100027373 (AKT3)
04914 Progesterone-mediated oocyte maturation
100027373 (AKT3)
04917 Prolactin signaling pathway
100027373 (AKT3)
04926 Relaxin signaling pathway
100027373 (AKT3)
04935 Growth hormone synthesis, secretion and action
100027373 (AKT3)
04919 Thyroid hormone signaling pathway
100027373 (AKT3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100027373 (AKT3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100027373 (AKT3)
09156 Nervous system
04725 Cholinergic synapse
100027373 (AKT3)
04728 Dopaminergic synapse
100027373 (AKT3)
04722 Neurotrophin signaling pathway
100027373 (AKT3)
09158 Development and regeneration
04380 Osteoclast differentiation
100027373 (AKT3)
09149 Aging
04211 Longevity regulating pathway
100027373 (AKT3)
04213 Longevity regulating pathway - multiple species
100027373 (AKT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100027373 (AKT3)
05205 Proteoglycans in cancer
100027373 (AKT3)
05207 Chemical carcinogenesis - receptor activation
100027373 (AKT3)
05208 Chemical carcinogenesis - reactive oxygen species
100027373 (AKT3)
05230 Central carbon metabolism in cancer
100027373 (AKT3)
05231 Choline metabolism in cancer
100027373 (AKT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100027373 (AKT3)
09162 Cancer: specific types
05210 Colorectal cancer
100027373 (AKT3)
05212 Pancreatic cancer
100027373 (AKT3)
05225 Hepatocellular carcinoma
100027373 (AKT3)
05226 Gastric cancer
100027373 (AKT3)
05214 Glioma
100027373 (AKT3)
05221 Acute myeloid leukemia
100027373 (AKT3)
05220 Chronic myeloid leukemia
100027373 (AKT3)
05218 Melanoma
100027373 (AKT3)
05211 Renal cell carcinoma
100027373 (AKT3)
05215 Prostate cancer
100027373 (AKT3)
05213 Endometrial cancer
100027373 (AKT3)
05224 Breast cancer
100027373 (AKT3)
05222 Small cell lung cancer
100027373 (AKT3)
05223 Non-small cell lung cancer
100027373 (AKT3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100027373 (AKT3)
05170 Human immunodeficiency virus 1 infection
100027373 (AKT3)
05161 Hepatitis B
100027373 (AKT3)
05160 Hepatitis C
100027373 (AKT3)
05164 Influenza A
100027373 (AKT3)
05162 Measles
100027373 (AKT3)
05168 Herpes simplex virus 1 infection
100027373 (AKT3)
05163 Human cytomegalovirus infection
100027373 (AKT3)
05167 Kaposi sarcoma-associated herpesvirus infection
100027373 (AKT3)
05169 Epstein-Barr virus infection
100027373 (AKT3)
05165 Human papillomavirus infection
100027373 (AKT3)
09171 Infectious disease: bacterial
05132 Salmonella infection
100027373 (AKT3)
05135 Yersinia infection
100027373 (AKT3)
05152 Tuberculosis
100027373 (AKT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100027373 (AKT3)
05142 Chagas disease
100027373 (AKT3)
09164 Neurodegenerative disease
05010 Alzheimer disease
100027373 (AKT3)
05017 Spinocerebellar ataxia
100027373 (AKT3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100027373 (AKT3)
05418 Fluid shear stress and atherosclerosis
100027373 (AKT3)
05415 Diabetic cardiomyopathy
100027373 (AKT3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100027373 (AKT3)
04932 Non-alcoholic fatty liver disease
100027373 (AKT3)
04931 Insulin resistance
100027373 (AKT3)
04933 AGE-RAGE signaling pathway in diabetic complications
100027373 (AKT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100027373 (AKT3)
01524 Platinum drug resistance
100027373 (AKT3)
01522 Endocrine resistance
100027373 (AKT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100027373 (AKT3)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100027373 (AKT3)
Protein kinases [BR:
mdo01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100027373 (AKT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
FTA2
ABC1
PH_11
Motif
Other DBs
NCBI-GeneID:
100027373
NCBI-ProteinID:
XP_007481609
Ensembl:
ENSMODG00000006626
UniProt:
F7GEK1
LinkDB
All DBs
Position
2:144184281..144572337
Genome browser
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFVGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatacttccttttgaagacagatggctcattcataggatataaggag
aaacctcaagatgtggatttaccttatccccttaacaacttttcagtggcaaaatgccag
ctcatgaaaacagaacgaccaaagccaaacacatttattatcagatgcctccagtggacc
actgttatagaacgaacatttcatgtggatactccagaggaaagggaagaatggacagaa
gctatccaggctgtagcagacagacttcagaggcaagaagaggaaaggatgaactgtagt
ccaacttcacaaattgacaatataggagaagaggaaatggatgcttctacaactcatcat
aaaagaaagacaatgaatgactttgactatttgaaattattgggtaaaggcacttttggg
aaagtgattttggttcgagagaaggcaagtggaaaatattatgctatgaagattttgaag
aaagaagtaattattgcaaaggatgaagtggcacacactctaacagaaagcagagtatta
aaaaacactagacatccctttttaacatccttgaaatattctttccagacaaaagatcgt
ttgtgttttgtgatggagtatgttaatggaggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgcttctatggtgcagaaattgtctctgctttggac
tatctacattctggaaagattgtgtatcgtgatctcaagttggaaaatttgatgttggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggattacagatgca
gctacaatgaagacattttgtggtacacctgaataccttgcacctgaggtattagaagat
aatgactatggccgtgcagtggactggtggggtttgggggttgtcatgtatgaaatgatg
tgtgggagattaccattctacaaccaggatcatgagaaactttttgagctaatactaatg
gaggacattaaatttcctcgaactctttcttctgatgcaaaatccttactttcaggactc
ttaataaaagatccaaataaacgccttggtggaggtccggatgatgcaaaagaaattatg
aggcacagtttctttgttggagtaaattggcaagatgtatatgataaaaagctggtacct
ccttttaagcctcaagtaacgtctgagacagataccagatattttgatgaagaatttaca
gctcaaacaattacaataactccacctgaaaaatatgatgaagatggtatggactgcatg
gacaatgagagacggccacattttccacagttttcctactcagcaagtggacgagaataa
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