Monodelphis domestica (gray short-tailed opossum): 100028103
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Entry
100028103 CDS
T01031
Symbol
ERBB3
Name
(RefSeq) erb-b2 receptor tyrosine kinase 3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04020
Calcium signaling pathway
mdo04151
PI3K-Akt signaling pathway
mdo05205
Proteoglycans in cancer
mdo05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100028103 (ERBB3)
04012 ErbB signaling pathway
100028103 (ERBB3)
04020 Calcium signaling pathway
100028103 (ERBB3)
04151 PI3K-Akt signaling pathway
100028103 (ERBB3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100028103 (ERBB3)
05205 Proteoglycans in cancer
100028103 (ERBB3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100028103 (ERBB3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100028103 (ERBB3)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100028103 (ERBB3)
Protein kinases [BR:
mdo01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100028103 (ERBB3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
TM_ErbB1
Kinase-like
DUF4381
Motif
Other DBs
NCBI-GeneID:
100028103
NCBI-ProteinID:
XP_001378216
UniProt:
A0A5F8GP87
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Position
Un
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AA seq
1343 aa
AA seq
DB search
MRGFLALQALGWFLNLASSSEVGSSQAVCSGTLNGLSVTGDAENQYQTLYKLYDRCEVVM
GNLEIVLTGHSPDLSFLQWIREVTGYVLIAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRLNQLTEILAGGVYIERNDKLCHMDTIDWRDIVRDPQAEIVVKDNG
KNCPPCHESCGGKCWGPGPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCGGPRE
TDCFACRHFNNSGACVSLCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVIDHTS
CVRACPGDKMEVEKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHNIPALDPEKLNVFQTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNVNVTSLGLRSLKEVSAGRVYISANRQLCYHHSLNWTRLLRGPKEG
RLDIKHNRSKKDCVAEGRVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTQCNFLNGEP
REFAHEDECFSCHPECQPVEGNVTCYGSGSDACAQCVHFRDGPHCVNTCPHGLLGAKGPI
YKYSDAHGECLPCHENCTQGCKGPELHDCFGQPEGFSSKTHVAVGLAVVAGLVVITLVLL
LALLYWRGRKIQNKRAMRRYLERGESLEPLDPGEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGIWIPEGESIKIPVCIKVIEDRSGRQSFQAVTDHMLAIGSLDHTHIVRLLGLCPG
SSLQLVTQFLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
IWELMTFGDIPYKGLRLTEVPDLLEKGERLPQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRDSGSGLPPGAEPPALTDKELEEVETLEPELELELELEEEE
ELATTLGSALSLPLGTLSRPRGSQNFLSPSSGYMPMNQSNLGATRQGSMMRGSGERCPCP
ASLHQNSRGRLASESSEGRGTSSEAEFQEAESVCGSRSRSRSPRPRGDSAYHSQRHSLLT
PLTPLTPPGLEEEDVNGYVMPDTHTKGIPSSRDGTLSSSVGLSSILGTEEEEEEDEEYEY
MNQRRKQSLPRPPRPGSLEELGYEYMDVGSDLSASLGSTHSCPLHPVPILPATGTTPDED
YEYMNRRHGGGTPGGDYAAMGGCPEAEQGYEEMGSFQGTGHHAPCIHDAHLKPLRSLEAT
RSAFDNPDYWHSRLFSKASAQGT
NT seq
4032 nt
NT seq
+upstream
nt +downstream
nt
atgagggggttcctcgcgctgcaggcattgggctggttcctcaacctggccagcagttcg
gaggtgggcagctcacaggcagtatgctcagggaccctcaatggcctgagtgtgaccggt
gatgctgaaaaccagtaccagacactgtacaagctgtatgatcgctgtgaggtggtgatg
ggaaacctggaaattgtgcttacaggacatagccctgacctctccttcctgcagtggatc
cgggaggtaacaggatatgttctaattgcaatgaatgagttctctactctaccactcccc
aaccttcgtgtggtacgggggacccaagtctacgatgggaagtttgccatctttgtcatg
ctcaactacaacacaaactccagccatgccctacgccagctccgcctcaatcagctcaca
gagatcctggctgggggtgtttacattgaaaggaatgataaactttgtcacatggacaca
attgactggagggacatcgtgagggacccacaggctgagattgtggtcaaggataatggc
aaaaactgtcccccttgtcacgagtcctgtggggggaaatgctggggtcctggaccagaa
gactgccagacattgacaaagacaatctgtgccccacaatgcaatggccactgctttgga
cccaaccccaaccagtgctgccatgatgagtgtgcaggtggatgtggaggtccccgggag
acagactgctttgcatgccgacacttcaataacagtggagcctgtgtgtctctgtgccca
cagcccctggtctacaacaagctcaccttccaactggagcccaatcctcacactaaatac
cagtatggaggggtctgtgtggccagctgcccccataactttgtgatagatcacacctcc
tgtgtcagggcctgtcctggggacaagatggaggtagaaaagaatggattgaagatgtgt
gagccctgtggagggctgtgtccaaaagcctgtgaggggacaggctcagggagccgattt
cagactgtagattccagtaacattgatgggtttgtgaactgtaccaagatcttgggcaac
ctggacttccttatcactggactcaatggagacccctggcacaacataccagccctggat
cctgagaagctcaatgtttttcagacagttcgggagatcacaggttacctgaacatccag
tcatggcctccccacatgcacaatttcagtgtcttctccaacctaaccaccattggaggc
cggagtctctacaatcggggcttctcactgctgatcatgaaaaacgtgaatgtgacatcc
ttgggcctgaggtccctgaaagaagtcagtgctgggcgtgtctatatcagtgccaaccgg
cagctctgctaccaccactctctgaactggaccaggctgcttcggggaccaaaggaaggg
aggctggacatcaagcacaaccggtccaaaaaggactgtgtggcagagggccgagtgtgt
gacccgctatgctcctctgggggttgctggggccctgggcctggccagtgcttgtcctgt
cgcaactacagccgagggggagtctgtgtgacccaatgcaacttcctgaatggagaacct
cgagagtttgctcacgaggatgagtgcttctcctgccatcctgagtgccagcctgtggag
ggcaatgtcacctgctatggctcgggctcagatgcttgtgctcagtgtgtccacttcagg
gatgggccacactgtgtgaatacctgcccccatggcctcctgggtgccaaaggacccatc
tacaagtactctgatgctcatggagagtgtctaccttgccatgagaactgcactcaaggg
tgtaagggaccagagctccatgactgtttcggtcaaccagagggcttcagcagcaagacc
catgtggctgtgggcctggctgtggtagcagggctggtggtgattaccttggtcttattg
cttgccttactctactggcgagggcgaaagattcagaataagcgggcaatgagacgctac
ctggaacggggtgagagcttggagcctttggaccctggggagaaggccaacaaggtcttg
gcccgaatattcaaggaaacagagctgagaaaactcaaagtgcttggctcaggtgtcttc
ggaactgtgcacaagggcatttggatcccagaaggcgagtctatcaagatcccagtctgc
attaaggtcattgaagacaggagtggtcggcaaagtttccaggctgtgactgatcacatg
ttagccattggcagcttagatcacacccacattgttcggctgctggggctatgcccaggg
tcatcgttgcagctggtcacccaatttctgccactgggatcactgctggaccacgtacga
caacatcgaggggctctgggacctcagctactgctcaactggggcgtgcagatcgccaag
ggcatgtactacctggaggaacacggcatggtgcacagaaatctggctgcccgcaatgtg
ctgctcaagtctccaagtcaagtgcaggtggctgactttggggtggcagatctgttaccc
cctgacgataaacaactgctgcacagtgaagctaagaccccaatcaagtggatggccctg
gaaagcatccattttggaaaatatacacaccagagtgacgtctggagttacggtgtgaca
atatgggaactgatgacattcggggacataccctataaagggcttcgactgactgaggtg
cctgacctgctggagaagggagagcgtctcccacagccacagatttgcactattgatgtc
tacatggtcatggttaagtgctggatgattgatgagaacatacgaccaacattcaaagaa
ctggctaatgaattcacccgaatggctcgggatccaccccgctatctggtcatcaagaga
gatagtggttctgggctgcctcctggggctgagccccctgcccttactgacaaagaactg
gaggaggtggagactctggagccagagctggagctggaactggagctggaggaggaggag
gaactggccaccacactaggctctgccctcagcctgccacttggcacactgtcccgaccc
cgtgggagtcagaactttctgagtccttcctctggatatatgccaatgaatcagagtaac
cttggagccactagacagggttctatgatgcgtgggagtggtgaacgatgcccttgccca
gcctctctgcaccagaactcacgaggccgactcgcatcagaatcctcagaaggccgaggg
acaagctctgaggctgagttccaagaggcagagtctgtatgtggaagccggagccgaagc
cggagccctcggcctcgaggggacagtgcctatcattcccaacgccacagcctactcacc
ccactcaccccactcactccaccagggctagaggaagaggatgtcaatggttacgttatg
cctgacacacataccaaaggtattccctcttcccgggatggcacgctgtcatcatctgtg
ggcctcagttccattctgggtacagaagaggaagaggaagaagatgaggagtacgaatat
atgaatcagagaagaaagcagagtctgccaagaccccctaggccaggatctctggaagag
ctgggctatgagtacatggatgtgggatcggacctcagtgcctccttaggcagtacccac
agctgcccactccatcctgtgcctatcctgcctgctacaggaactactcccgatgaagat
tatgagtatatgaatcgtcgacatggtggaggaactccgggaggggattatgcagccatg
ggaggttgcccagaagcagagcaagggtatgaggaaatggggtcatttcagggcactggg
caccatgccccttgcatccatgatgcccacctcaagccccttcgaagcctagaggccact
cgctctgcttttgacaaccctgactactggcatagtagacttttctccaaggccagtgct
caggggacataa
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