Monodelphis domestica (gray short-tailed opossum): 100029256
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Entry
100029256 CDS
T01031
Symbol
SOS2
Name
(RefSeq) SOS Ras/Rho guanine nucleotide exchange factor 2
KO
K03099
son of sevenless
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01521
EGFR tyrosine kinase inhibitor resistance
mdo01522
Endocrine resistance
mdo04010
MAPK signaling pathway
mdo04012
ErbB signaling pathway
mdo04014
Ras signaling pathway
mdo04062
Chemokine signaling pathway
mdo04068
FoxO signaling pathway
mdo04072
Phospholipase D signaling pathway
mdo04150
mTOR signaling pathway
mdo04151
PI3K-Akt signaling pathway
mdo04510
Focal adhesion
mdo04540
Gap junction
mdo04630
JAK-STAT signaling pathway
mdo04650
Natural killer cell mediated cytotoxicity
mdo04660
T cell receptor signaling pathway
mdo04662
B cell receptor signaling pathway
mdo04664
Fc epsilon RI signaling pathway
mdo04714
Thermogenesis
mdo04722
Neurotrophin signaling pathway
mdo04810
Regulation of actin cytoskeleton
mdo04910
Insulin signaling pathway
mdo04912
GnRH signaling pathway
mdo04915
Estrogen signaling pathway
mdo04917
Prolactin signaling pathway
mdo04926
Relaxin signaling pathway
mdo04935
Growth hormone synthesis, secretion and action
mdo05034
Alcoholism
mdo05160
Hepatitis C
mdo05161
Hepatitis B
mdo05163
Human cytomegalovirus infection
mdo05165
Human papillomavirus infection
mdo05200
Pathways in cancer
mdo05205
Proteoglycans in cancer
mdo05206
MicroRNAs in cancer
mdo05207
Chemical carcinogenesis - receptor activation
mdo05208
Chemical carcinogenesis - reactive oxygen species
mdo05210
Colorectal cancer
mdo05211
Renal cell carcinoma
mdo05213
Endometrial cancer
mdo05214
Glioma
mdo05215
Prostate cancer
mdo05220
Chronic myeloid leukemia
mdo05221
Acute myeloid leukemia
mdo05223
Non-small cell lung cancer
mdo05224
Breast cancer
mdo05225
Hepatocellular carcinoma
mdo05226
Gastric cancer
mdo05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100029256 (SOS2)
04012 ErbB signaling pathway
100029256 (SOS2)
04014 Ras signaling pathway
100029256 (SOS2)
04630 JAK-STAT signaling pathway
100029256 (SOS2)
04068 FoxO signaling pathway
100029256 (SOS2)
04072 Phospholipase D signaling pathway
100029256 (SOS2)
04151 PI3K-Akt signaling pathway
100029256 (SOS2)
04150 mTOR signaling pathway
100029256 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100029256 (SOS2)
04540 Gap junction
100029256 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100029256 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100029256 (SOS2)
04660 T cell receptor signaling pathway
100029256 (SOS2)
04662 B cell receptor signaling pathway
100029256 (SOS2)
04664 Fc epsilon RI signaling pathway
100029256 (SOS2)
04062 Chemokine signaling pathway
100029256 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
100029256 (SOS2)
04912 GnRH signaling pathway
100029256 (SOS2)
04915 Estrogen signaling pathway
100029256 (SOS2)
04917 Prolactin signaling pathway
100029256 (SOS2)
04926 Relaxin signaling pathway
100029256 (SOS2)
04935 Growth hormone synthesis, secretion and action
100029256 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100029256 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
100029256 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100029256 (SOS2)
05206 MicroRNAs in cancer
100029256 (SOS2)
05205 Proteoglycans in cancer
100029256 (SOS2)
05207 Chemical carcinogenesis - receptor activation
100029256 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
100029256 (SOS2)
05231 Choline metabolism in cancer
100029256 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
100029256 (SOS2)
05225 Hepatocellular carcinoma
100029256 (SOS2)
05226 Gastric cancer
100029256 (SOS2)
05214 Glioma
100029256 (SOS2)
05221 Acute myeloid leukemia
100029256 (SOS2)
05220 Chronic myeloid leukemia
100029256 (SOS2)
05211 Renal cell carcinoma
100029256 (SOS2)
05215 Prostate cancer
100029256 (SOS2)
05213 Endometrial cancer
100029256 (SOS2)
05224 Breast cancer
100029256 (SOS2)
05223 Non-small cell lung cancer
100029256 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
100029256 (SOS2)
05160 Hepatitis C
100029256 (SOS2)
05163 Human cytomegalovirus infection
100029256 (SOS2)
05165 Human papillomavirus infection
100029256 (SOS2)
09165 Substance dependence
05034 Alcoholism
100029256 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100029256 (SOS2)
01522 Endocrine resistance
100029256 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
PH
IQ_SEC7_PH
PH_19
Motif
Other DBs
NCBI-GeneID:
100029256
NCBI-ProteinID:
XP_001379052
Ensembl:
ENSMODG00000011821
UniProt:
F6YCI3
LinkDB
All DBs
Position
1:277429760..277559159
Genome browser
AA seq
1328 aa
AA seq
DB search
MQPPQQPYDFSSEENHPKWRGLFVPALRKVQQQVHPNLSAKEDSLYYIEELILQLLSKLC
IAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRTPLLLPVDKIHPLLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPFSSGELNYYDLVRTEIAEERQYLRELNLIIKVFREAFLSNKKLFASSDI
EGIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPQFHERFNTLMAKPAVSLHFQSIADGFKEAVRYVLPRLMLVPVYHCSHYFELLEQLQE
CSEEQEDRECLKQAITALLNFRCSMERICNKHSPRRRPADPVCRFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLMRIGAKHERHIFLFDGLMISCKTNHGQSRIPG
YSNAEYRLKEKFIMRKVQICDKDDTCEYKHAFELISKDENSILFAAKSIEEKNNWMAALI
SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNSQSGIPIIKGG
TVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLKLLIERFEIPEPEPTEADKLAVE
KGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISTVKGK
TMKKWVESIVKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQYESFDLMTLHPIEI
ARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAEN
FEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEA
VELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKQGKELINFSKRRKV
AEITGEIQQYQNQPYCLRIESEIRRFFENLNPMGNTSEKEFTDYLFNKSQEIEPRNCKQP
PRFPRKTTFSLKSPGIRPHAGRHGSTSGTLRGHPTPLEREPCKISFSRINEAEHESTASA
PTSPNTPSTPPVSASSDLSVFLDIDLNSSYGSNSIFAPVVLPHSKSFFSSCGSLHKLSEE
PLVPPPLPPRKKFDQDVSTSKGNLKYDDDPPAIPPRQPPPPKIKPRVPAYGGPFDGPLPS
PPPPPPRDPLPETPPPVPLRPPEHFINYPFNLQPPPMGHAHRDPEWFREASTCPNSPNTP
PSTPSPRVPRRCVLSSSQNNLAHSQAPPIPPRQNSSPHLPKLPPKTYKRDLCQPPMYRLS
LLEHAETP
NT seq
3987 nt
NT seq
+upstream
nt +downstream
nt
atgcagccgcctcagcaaccctacgatttctccagcgaagagaaccacccgaaatggcgg
ggactcttcgtcccggccctgcggaaggttcagcagcaagttcaccccaacctctcagca
aaagaagattctctctattatattgaagagttgatccttcaactgctaagtaaattatgc
attgcacagccaaggacagttcaagatgtagaggagcgtgttcaaaagacttttcctcat
ccaattgacaagtgggctattgctgatgcccagtctgccatagaaaaacgaaaacgaagg
acccctctcttgttacctgtggataaaattcatcctttattgaaggaagttttagggtat
aaagtagattatcatgtctctctttatattgtggctgtattggagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatcagacattatgaaatatcccagcag
gacattaaagtatcaatgtgtgcggataaggttttaatggacatgtttgatcaggatgat
attggtttggtttcactttgtgaagatgaacccttttcttcaggtgaattaaattactat
gaccttgtcagaactgaaattgcagaagaaagacaatatctacgggaattaaatcttata
ataaaagtatttcgagaggctttcctttcaaacaaaaagctgtttgcatcttcggacatt
gaagggatattcagcaatattttagatattcatgaattgactgtaaagttattaggcttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatctagcagaagaacaagcatttgatccatatgaaaccttgtcacaagatatt
ctttcaccacagtttcatgagcgtttcaatactttgatggccaaacctgctgtttctcta
cattttcagtccattgctgatggctttaaggaggctgtacggtatgttcttccacgcctt
atgctagtaccagtttaccattgttcacactactttgaattattggagcaattgcaagaa
tgcagtgaagaacaagaagatagagaatgtttgaaacaagctattactgctcttctgaat
ttccgatgtagcatggaacggatttgcaacaagcattcacctaggcggcgacctgcggat
cctgtttgtcgattttataaccgtcaattacggagcaagcacctagccattaaaaaaatg
aatgaaattcaaaaaaatattgatggatgggaaggcaaagatattggccagtgttgtaat
gaatttattatggaaggcccattgatgagaataggagctaagcatgaacgtcatattttt
ctttttgatggcttaatgattagctgtaaaactaatcatggacaatcccggattccaggt
tatagcaatgcagaatacagattgaaagaaaaatttatcatgaggaaagtacaaatctgt
gacaaagatgacacttgtgagtacaagcatgcctttgagttgatttccaaagatgaaaac
agcattctatttgctgctaaatccattgaagagaaaaataattggatggcagccttaatt
tctcttcagtatcgtagtacactagatcgaatgctagattcagtattattaaaagaagaa
aatgaacagccactgaggttgccaagtccagaagtttatcgctttgttgttaaagactct
gaagaaaatattgtttttgaagacaattctcaaagtggaatcccaatcattaaaggagga
actgtggtgaaattaattgaaagactaacctaccatatgtatgcagatcccaattttgtg
cgtacttttcttacaacctatcgttcattttgtaaaccacaggaattgttgaagttatta
attgaacggtttgaaatcccagagccagaacctacagaagcagataaattagcagtggag
aaaggagaacaaccaatcagtgcagatctgaaacgctttcgcaaagaatatgtccaacca
gtacaacttaggattctaaatgtatttcggcactgggtagaacatcatttttatgatttt
gagagagatctggagttacttgaaagattagaatcctttatatcaactgtaaaaggaaaa
accatgaagaagtgggtagaatcaattgttaaaatcatcaagaggaaaaaacaagctcag
gcaaatggaattagccataatattacttttgaaagtccaccaccaccaattgagtggcat
attagcagaccaggacagtatgagtcatttgatcttatgacccttcatccaatagaaatt
gcacgtcaactaacacttctggaatctgacctctacagggcagttcagccttctgaactt
gtgggaagtgtgtggactaaagaagataaggaaataaattctccaaatttattgaaaatg
attcggcataccaccaatcttactctttggtttgaaaagtgtatagtagaagcagaaaac
tttgaagaacgagtggcagtgttaagtaggattatagaaattctacaagtttttcaagat
ttgaacaatttcaatggtgtattggagatagttagtgctgtgaattcagtgtctgtgtat
agattggaccacacatttgaagcattgcaggaaagaaaacggaagattttagatgaagct
gtagaactaagccaagatcactttaaaaaatacctagcaaaacttaaatcaatcaaccca
ccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaagggaat
aatgacttccttaagaaacaagggaaagaattaatcaactttagtaaaagaaggaaagta
gctgaaattactggagagattcagcagtatcagaatcagccttattgtttacggatagaa
tcagaaataaggaggttctttgaaaatctcaaccccatgggaaatacatcagagaaagaa
tttacagattatttattcaataaatcacaagaaattgaaccccgaaactgtaaacagcca
cctcgatttcctaggaaaacaactttctccttaaaatctcctggcataagaccacatgct
ggcagacatggctctacttcaggcactttacgaggtcacccaacaccattagaaagagaa
ccatgtaaaataagcttcagtcggataaatgaggctgagcatgagtcaacagcatcagca
ccaacctctccaaatacaccatctactccaccagtctctgcttcttcagaccttagtgta
tttttagatatagatcttaacagttcttatggaagtaacagcatctttgccccagtggtc
ttaccacattcaaaatctttcttcagttcatgtggtagtttacataaattaagtgaagag
ccactggttcctcctcctcttcctcctcgtaaaaagtttgatcaagatgtttcaacctct
aagggaaacttgaaatatgatgatgatcctcctgctattccaccaaggcaaccgcctccc
ccaaagataaagcctcgagttcctgcttatggtggtccatttgacgggcccttacctagt
ccaccaccaccacctccacgagaccctcttcctgaaactcctccaccagtaccacttcgg
cctcctgaacatttcataaactatccgtttaatcttcagccaccaccaatggggcatgct
cacagagatccagagtggttccgggaagccagtacatgtccaaactcaccaaatactcct
ccaagcacaccctctccaagggtgccacgtcgctgcgtgctcagttctagtcaaaataat
cttgcccattctcaagctcccccaatcccaccaagacagaattcaagccctcacttacca
aaactgccgccaaagacttacaaacgagatctttgtcaacctcctatgtacagattgtca
ttgttagaacatgcagaaacaccttag
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integrated database retrieval system
