Methylacidimicrobium sp. AP8: MTHMO_0114
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Entry
MTHMO_0114 CDS
T06915
Symbol
cysG
Name
(GenBank) Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
meap
Methylacidimicrobium sp. AP8
Pathway
meap00860
Porphyrin metabolism
meap01100
Metabolic pathways
meap01110
Biosynthesis of secondary metabolites
meap01120
Microbial metabolism in diverse environments
meap01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
meap00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MTHMO_0114 (cysG)
Enzymes [BR:
meap01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MTHMO_0114 (cysG)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MTHMO_0114 (cysG)
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
DUF817
Motif
Other DBs
NCBI-ProteinID:
CAB4242460
UniProt:
A0A7R8QFM5
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Position
I:125050..126579
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AA seq
509 aa
AA seq
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MSAAPPTGKVYLVGAGPGDPGLLTLRGREVLAEADSIFYDALCAPELLQWAKPGAQKIFV
GKSSGRQAFSQREIESLLIRQARRGERVVRLKGGDPFLFGRGGEECLALEAAGVPFEVVP
GITSALAAPAYAGIPLTHRGVASAVTIVTGHEDPSKPEISVDWVALGGLEGTKVILMGAE
RLAEISRRLLEGGEREQCPVAAIRWGTFGKQEVREGTLQQAAGGEFSVEPPSVIVVGEVV
KLRSRLSWREGLPLHGQRIVVTRTRCESSRLGKRLRELGADVLEIPTIRRVPRPFGEEQR
DLVRRLASDFTWILLTSPYGADLFLRHVWETTGDVRALGGLRIAAVGSATADAVRRFHLS
VDRMPESYTTSALAGCFSAQEIRGGRFCLARSSRGNPELPEALRRSGAHVSEWVLYDTEP
ETGDPTGAKARFLAGGADWVLFASSSAVENWHRLALHPRPGAPSPRIVSIGPVTTRALKR
FGLSVAAEAERHSVDGLVACLIDCVQKEK
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgagtgctgctcctccgacgggcaaggtctatctggtcggtgccggaccgggagatccc
gggctcctcaccctccgcgggcgggaggtcctggcggaggccgactcgatcttctatgac
gccctttgcgcgccggagctcttgcaatgggcgaagcccggagcgcaaaagattttcgtc
ggaaaatcgagcggacggcaggccttttcccaaagggagatcgagtcgttgcttatccgc
caggcccggagaggggagcgggtcgtccggctcaagggaggagatccgttcctcttcggg
cgcggcggagaggagtgcctggcgctggaagcagcgggagtccctttcgaggtcgttccg
gggatcacgtccgccttggcggcgccggcttatgccgggatcccgttgacgcatcgcggt
gtggcttccgcggtgaccattgtgaccggtcatgaggatccgtcgaagccggaaatatcg
gtcgactgggttgccttgggagggttggaaggcaccaaggtcatcttgatgggagcggaa
aggctcgcggaaatcagccgccggcttctggaggggggcgagcgagagcagtgtccggtc
gccgccattcggtggggcaccttcgggaagcaggaggtgcgggaaggcaccctgcagcag
gcggccggaggcgagttttccgtcgagccgccctccgtcatcgtcgtcggagaggtcgtc
aagttgcgcagccggcttagttggcgagaagggctccctcttcacggacagcggatcgtc
gtaacgcgcacccgctgcgagtcgagccggctcggaaaacggttacgcgagctcggagcc
gatgtcctcgagattccgacgatccgtagggttccccgtcctttcggcgaggagcagcgg
gacctggtgcgccgcttggcctccgacttcacgtggattctgttaaccagcccttacggc
gccgatctctttctgcggcatgtctgggagacgaccggggacgtccgcgctctgggcggg
ctccggatcgccgcggtcgggagcgcgacggcggatgcggtccggcggtttcatctttcg
gtcgatcggatgcccgagagctatacaacctcggcgctggcgggctgcttttccgcgcag
gagatccgcggaggcaggttctgcctggcgcggagctcccggggaaaccccgagctgccg
gaagcgttgcgacgatcgggagctcatgtgagcgagtgggtgctttacgacacggaaccg
gaaaccggcgatcccaccggcgctaaggctcggtttctggcaggaggagcggactgggtt
ttgtttgcaagctcaagcgccgttgagaattggcaccggctcgccctccatccccggccg
ggggccccatcgcctcggatcgtgagcatcggccccgtcacgacccgggccttgaagcgt
tttggactttccgttgccgccgaagccgaaagacattcggtcgacggtcttgttgcgtgc
ctgatcgactgtgttcagaaggaaaaatag
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