Microtus fortis (reed vole): 126491593 Help Entry 126491593         CDS       T08493                                  Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism mfot  Microtus fortis (reed vole) Pathway mfot04010   MAPK signaling pathway mfot04014   Ras signaling pathway mfot04015   Rap1 signaling pathway mfot04022   cGMP-PKG signaling pathway mfot04066   HIF-1 signaling pathway mfot04068   FoxO signaling pathway mfot04072   Phospholipase D signaling pathway mfot04150   mTOR signaling pathway mfot04151   PI3K-Akt signaling pathway mfot04152   AMPK signaling pathway mfot04211   Longevity regulating pathway mfot04213   Longevity regulating pathway - multiple species mfot04520   Adherens junction mfot04910   Insulin signaling pathway mfot04913   Ovarian steroidogenesis mfot04923   Regulation of lipolysis in adipocytes mfot04930   Type II diabetes mellitus mfot04931   Insulin resistance mfot04932   Non-alcoholic fatty liver disease mfot04960   Aldosterone-regulated sodium reabsorption mfot05010   Alzheimer disease mfot05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mfot00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     126491593    04014 Ras signaling pathway     126491593    04015 Rap1 signaling pathway     126491593    04066 HIF-1 signaling pathway     126491593    04068 FoxO signaling pathway     126491593    04072 Phospholipase D signaling pathway     126491593    04022 cGMP-PKG signaling pathway     126491593    04151 PI3K-Akt signaling pathway     126491593    04152 AMPK signaling pathway     126491593    04150 mTOR signaling pathway     126491593  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     126491593  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     126491593    04923 Regulation of lipolysis in adipocytes     126491593    04913 Ovarian steroidogenesis     126491593   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     126491593   09149 Aging    04211 Longevity regulating pathway     126491593    04213 Longevity regulating pathway - multiple species     126491593  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     126491593   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     126491593   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     126491593    04932 Non-alcoholic fatty liver disease     126491593    04931 Insulin resistance     126491593  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mfot01001]     126491593   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mfot04090]     126491593 Enzymes [BR:mfot01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      126491593 Protein kinases [BR:mfot01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    126491593 CD molecules [BR:mfot04090]  Proteins   126491593 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  126491593 NCBI-ProteinID:  XP_049983298 LinkDB All DBs Position Unknown AA seq 1382 aa AA seqDB search MGSGKRRETLPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQI LLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVI FEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEEC GDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGN CSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPGCH QYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGCTV INGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEI GNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEISGTKGRQERN DIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNV TEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWE RQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKPSAGSGAEDTRPSRKRRSLEEVGNVTATMPTLPDF PNTSSTIAPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMT AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDN CPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEME FEDMENVPLDRSSHCHREEAGGREGGSTLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggctccgggaaacgacgtgagaccttgccgttgctggtggccgtggccgcgttgctg gtgggcgcagccggccacctgtaccccggcgaggtgtgccctggcatggacatcaggaac aacctgaccaggctgcatgagctggagaactgctcagtcatcgagggccatctgcagatc ctcttgatgttcaaaaccagacccgaagatttccgagacctcagtttccccaaactcatc atgatcacagactacctgcttcttttccgtgtctatggcctggagagtttgaaagacctc ttccccaaccttacagtcatccgaggctcccgcctcttcttcaactatgccctggtcatc tttgagatggtccacttgaaggagctggggctctacaacctcatgaacatcacccggggc tctgtccgcattgagaagaataatgagctctgttacctggccaccattgactggtctcgg atcttggattctgtggaggacaactacatcgtgctgaacaaagatgacaatgaggagtgt ggggatgtctgtccaggcactgccaagggcaagaccaactgccctgccaccgtcatcaat gggcagtttgtggaacggtgctggacacacagtcattgtcagaaagtttgtccgaccatc tgtaagtcacatggctgcacagctgaaggcctgtgctgccacaaggagtgcctaggcaac tgttcggaacccgatgaccccaccaagtgtgtggcctgtcgcaacttctacctggatggt cgctgtgtggagacctgcccgcccccttactaccacttccaggattggcgctgtgtgaac ttcagcttctgccaagaccttcactacaaatgcagaaactctaggaagcccggctgtcac caatacgtcattcacaacaacaagtgcatcccggagtgtccttctggctatacaatgaat tccagcaacttaatgtgcaccccgtgtctgggaccctgccctaaggtctgccaaatcctc gacggcgagaagaccattgactctgtgacatctgcccaggagctccgaggctgcactgtg atcaatggcagcctgatcatcaacattcgaggaggcaacaatctggcagctgagctggag gctaaccttggcctcattgaagaaatctcagggttcctaaagatccggcgctcctatgct ctagtatcgctttctttcttccggaagctacatctgattcgaggagagaccttggaaatc gggaactactctttctatgccttggacaaccagaacctcaggcagctctgggactggagc aagcacaacctcaccatcactcagggcaagctcttcttccactacaaccccaaactctgc ttgtcagaaatccataagatggaagagatttctggaactaagggccgccaggagaggaac gacattgccctgaagaccaatggggaccaggcatcctgtgaaaatgagttacttaaattt tctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactggccccct gacttccgagacctcttgggattcatgcttttctacaaagaggccccttatcagaatgtg acggagtttgatggtcaggatgcttgtggctccaacagctggactgtggtagatattgac ccaccccagaggtccaacgaccccaagtctcaaaccccaagccaccctgggtggctaatg cggggtctcaagccctggacccaatatgccatctttgtcaagaccttggttaccttctca gatgaacgccggacctacggagccaaaagtgacatcatctatgtgcagacagatgccacc aatccttctgtccccctggaccccatatcggtttctaattcctcatctcagattatctta aagtggaagcccccctctgaccccaacggcaacatcacacactacttggtctactgggag aggcaggcagaggacagcgagctgtttgagttggattattgtctcaaagggctgaagctc ccctcacggacctggtccccaccttttgagtctgatgattctcagaagcacaatcagagc gagtatgacgattcagccagcgaatgctgttcctgccccaagaccgactctcagatcctg aaggagctggaagagtcttcgtttaggaagacctttgaggattacctgcataatgtggtt tttgtccccagaaaaccctctgcaggcagtggtgccgaggacactaggccatctcgaaag cgaagatcccttgaagaggtggggaatgtgacagccaccatgcctacacttccagatttt cctaacacctcctccaccattgcacctacgagtcaggaggaacacaggccatttgagaaa gtggtgaacaaggagtcacttgtcatctctggcctgagacacttcactggctatcgcatt gagctgcaggcatgcaaccaagactccccagaagagaggtgcagtgtggctgcctacgtc agtgcccggaccatgcctgaagctaaggcagatgacattgttggccctgtgacccacgaa atctttgagaacaatgttgtacacttaatgtggcaagaaccaaaggaacccaatggtctg attgtgctgtatgaagtgagctatcggcgatatggcgatgaggagctgcacctctgtgtc tccaggaagcattttgccctggagcggggctgcaggcttagagggctctccccagggaac tacagtgttcgagtccgggctacctccctggcaggcaatggctcctggacagaacccacc tatttttacgtgactgattatttagatgtcccatcaaatattgccaaaattatcatcggg cccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctattcctgaga aagaggcagccagatgggccgatgggaccattgtatgcatcttcaaaccctgaatacctc agtgccagtgatgtgtttccttcttctgtgtacgtgccggatgagtgggaggtgcctcga gagaagatcacccttctacgagagctggggcagggatcctttggtatggtgtatgagggc aatgccaaggatatcatcaagggtgaggcagagacccgtgttgcagtgaagactgtcaat gagtcagccagtctccgagaacggatcgagttcctcaacgaggcatcggtcatgaaggga ttcacctgccatcatgtggttcgcctccttggggtggtatccaaaggccagccaacactg gtagtgatggaattgatggctcatggagacctgaagagtcacctccgttccctgcgcccg gatgctgaaaataacccaggccgtcctccccctaccttgcaagagatgattcagatgaca gcagaaattgctgatggcatggcatacttgaatgccaagaagtttgtgcaccgggacctg gcagctcgaaactgcatggttgctcatgattttaccgtcaaaattggagactttgggatg acgagagacatctatgagacagattactatcggaaagggggcaagggcttgctgcctgta cggtggatgtcacctgagtccttgaaggacggagtctttactgcttcttctgatatgtgg tcctttggggtggtcctttgggaaatcactagcctggctgagcaaccataccaaggcctg tctaacgaacaggtgttgaaatttgtcatggatggaggctatctggatccacctgataat tgtcctgagagactcactgacctgatgcgcatgtgctggcagttcaaccccaagatgagg ccaaccttcctggaaattgtcaacctgctgaaggatgacctccaccccagctttccagag gtttccttcttctacagcgaagagaacaaggctcccgagagtgaggagctggagatggag ttcgaggacatggagaatgtccccttggatcggtcctctcactgtcacagggaagaagct gggggccgggagggagggtccactctgagcatcaaacggacctatgatgaacacatccca tacacccacatgaacgggggcaagaagaatgggcgtgtgctcaccctgcccaggtcaaac ccttcctaa

DBGET integrated database retrieval system