Microtus fortis (reed vole): 126515030
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Entry
126515030 CDS
T08493
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mfot
Microtus fortis (reed vole)
Pathway
mfot00010
Glycolysis / Gluconeogenesis
mfot00020
Citrate cycle (TCA cycle)
mfot00620
Pyruvate metabolism
mfot00785
Lipoic acid metabolism
mfot01100
Metabolic pathways
mfot01200
Carbon metabolism
mfot01210
2-Oxocarboxylic acid metabolism
mfot04066
HIF-1 signaling pathway
mfot04922
Glucagon signaling pathway
mfot05230
Central carbon metabolism in cancer
mfot05415
Diabetic cardiomyopathy
Module
mfot_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mfot00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
126515030
00020 Citrate cycle (TCA cycle)
126515030
00620 Pyruvate metabolism
126515030
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
126515030
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
126515030
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
126515030
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
126515030
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
126515030
Enzymes [BR:
mfot01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
126515030
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
126515030
NCBI-ProteinID:
XP_050020315
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agcagagtgctagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcggcgaatggagctaaaggcagatcag
ctatataaacagaaaattatccgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgtgtgggcctagaggccggcataaaccccacggaccatctcatcacagcctatcgagct
catggcttcaccttcactcggggcctgcctgtccgagcaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggcggatcgatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctaggagcagggattgctctggcc
tgcaaatacaatggaaaagatgaggtctgtttgacattatatggcgatggcgctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaactaccttgtattttc
atctgtgagaataaccgctatggcatggggacatctgtcgagagagcggcggccagcaca
gattactacaaaagaggagattttattcctggactgagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcatattgtaggtctggtaaggggcccatc
ctgatggagctacagacttaccgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaagatgctgcccagtttgctacagctgatccagagccaccc
ttggaggaactaggctatcacatctacagtagtgatcctccctttgaagtgcgtggtgcc
aaccaatggatcaagtttaagtccgtcagttaa
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