Mycolicibacterium grossiae: FZ046_09720
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Entry
FZ046_09720 CDS
T06593
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mgro
Mycolicibacterium grossiae
Pathway
mgro00860
Porphyrin metabolism
mgro01100
Metabolic pathways
mgro01110
Biosynthesis of secondary metabolites
mgro01120
Microbial metabolism in diverse environments
mgro01240
Biosynthesis of cofactors
Module
mgro_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mgro_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mgro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
FZ046_09720
Enzymes [BR:
mgro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
FZ046_09720
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
FZ046_09720
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Ortholog
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEM45021
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Position
2019945..2021591
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AA seq
548 aa
AA seq
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MTTRRKHKPGHITFVGSGPGDPGLLTTRARAVLANAALAFIDPDVPEAVLALIGCELPPP
SGPEAPSAADDAADADAPAALPGGVDVRPALGDPAEVAKILVNESRAGSDVVRLVAGDPL
SVDSVLAEVNAVARTQAHFEIVPGLPATTAVPTYAGLPLGSAHTVADVRGDVDWAALAAA
PGPLILHATASHLPDAARTLIEYGLTDTTPVVVTANGTTCQQRSVETTLVGLLDKATLEK
PVGSEPAGPLTGPLVATIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSDRLVSH
GALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEFGLDARA
FSGVKIACVGQATADRVRAFGINPELVPTGEQSSLGLLDEFPPYDDIFDPVNRVLLPRAD
IATETLAEGLRERGWEIEDVTAYRTVRAAPPPAQTREMIKTGGFDAVCFTSSSTVRNLVG
IAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVEALAEHAARLRAEGALPP
PRKKSRRR
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgacgacccgacgtaagcacaagcccggccacatcacgttcgtgggctcggggccggga
gacccgggcctgctgaccacgcgggcccgcgcggtgctggccaacgcggcgctggcgttc
atcgatcccgacgtgccggaggcggtgctcgccctgatcggctgcgagctgccgccgccg
tcgggaccggaggcgcccagcgcggccgacgacgccgccgatgccgacgccccggcggcc
ctgccgggtggcgtggacgtgcggcccgcgctcggcgatcccgccgaggtggccaagatc
ctggtgaacgagtcccgcgcgggctccgacgtcgtgcgactggtggccggtgacccgctg
tcggtggactcggtgctcgccgaggtcaacgccgtggcgcggacgcaggcgcacttcgag
atcgtgccgggcctgcccgccaccaccgccgttccgacctacgccgggctaccgctcggc
tcggcgcacaccgtcgccgacgtgcgcggcgacgtcgactgggcggcgctggccgccgcg
ccgggcccgctgatcctgcacgccacggcctcgcacctgccggacgccgcgcgcaccctc
atcgagtacggcctgaccgacacgacgccggtcgtcgtcaccgccaacggcacgacgtgc
cagcagcgttcggtggagaccacgctggtgggtctgctggacaaggcgacgctcgagaag
cccgtcggcagcgagcctgccggtccgctcaccggcccgctggtcgcgacgatcggcaag
accgtcgccaaccgcgccaagctgaactggtgggagagccgcgccctgtacggctggacc
gtgctggtgccgcgcaccaaggaccaggccggcgagatgagcgaccgcctggtctcgcac
ggcgccctgccgatcgaggtgccgaccatcgccgtcgagccgccccgcagcccggcgcag
atggagcgcgccgtcaagggtctggtggacggccggttccagtgggtcgtgttcacctcg
accaacgcggtgcgggcggtgtgggagaaattcaacgagttcggcctggacgcccgggcg
ttctccggagtgaagatcgcgtgcgtcggtcaggcgaccgccgaccgggtccgcgccttc
ggcatcaatcccgaactggtcccgaccggtgagcagtcctcgctggggctgctcgacgag
ttcccgccctacgacgacatcttcgacccggtgaaccgggtgctgctgccgcgcgcggac
atcgccaccgagacgctggccgaggggctgcgcgaacgcggctgggagatcgaggacgtc
acggcgtaccgcacggtgcgtgccgcgccgccgcccgcgcagacgcgcgagatgatcaag
accggcggtttcgacgcggtgtgcttcacgtcgagttcgacggtgcgcaacctcgtcggc
atcgcgggcaagccgcacgcacggaccatcgtggcgtgcatcgggcccaagaccgccgag
accgcagcggaattcgggctgcgcgtcgacgtgcagcccgagacggccgcggtcggcccg
ctggtcgaggcgctcgccgagcacgccgcccggctgcgcgccgagggtgccctgccgccg
ccgcgcaagaagagtcgccgccgctga
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