Mycobacterium haemophilum: B586_19460
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Entry
B586_19460 CDS
T04111
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mhad
Mycobacterium haemophilum
Pathway
mhad00860
Porphyrin metabolism
mhad01100
Metabolic pathways
mhad01110
Biosynthesis of secondary metabolites
mhad01120
Microbial metabolism in diverse environments
mhad01240
Biosynthesis of cofactors
Module
mhad_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mhad_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mhad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
B586_19460
Enzymes [BR:
mhad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
B586_19460
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
B586_19460
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AKN18263
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Position
611948..613654
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AA seq
568 aa
AA seq
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MTTRGRKPRPGRITFVGAGPGAPGLLTTQAAAVLANAALVFIDPDVPEPVLALIGKDLPP
VSGPAPAGPAAAAGGAAEGAPDGDHNHAAPAVMSGGADIRPALGDPTEVAKMLTAEARSG
ADVVRLVAGDPLTVDAVITEVNAVARTHLHIEIVPGLAASSAVPTYAGLPLGSSHTVADV
RDPHVDWDALAAAPGPLILQATASHLADAARTLIDHGLAEATPCVVTAQGTTCQQRSVET
TLAGLADPAVLSGALQDQGAKLSPSGGDPLTGPLVVTIGKTVTSRAKLNWWESRALYGWT
VLVPRTKDQAGEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTS
TNAVRAVWEKFGEFGLDARAFSGVKIACVGEATADRVRAFGISPELVPAGEQSSLGLLDE
FPPYDSVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGP
LVDALAEHAARLRAEGALPPPRKKSRRR
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgcaagccgagaccgggccgcatcacctttgtgggcgccggtcca
ggcgccccgggattactgactacccaggctgccgcggtgctggcaaacgccgcactggtt
ttcatcgaccccgatgtacctgagccggtgttggcgctgattggcaaggacctgccaccg
gtctctggcccggcacccgccggtccggctgcggccgctggcggcgctgccgagggtgct
cccgatggggatcacaaccacgccgcaccggcggtcatgtccggtggcgccgacatccgt
cctgcgctgggtgatcccaccgaggtcgccaagatgctgaccgccgaggctcgttcgggt
gccgacgtggtgcggctggtggcgggtgatccgttgacggtggacgcggtcatcaccgag
gtgaacgccgtggcacgcacccacctacacatcgagattgtgcctggcttggccgccagc
agcgctgtcccgacctatgccgggctgccgctgggttcgtcgcacacggtggctgatgtg
cgtgacccacatgtggattgggacgcgttggccgcggctcccgggccgctgattctgcaa
gccaccgcatcacatctggccgacgcggcgcgcaccctgatcgaccacgggctggccgag
gccacaccctgcgtggtgactgcgcagggcacgacctgccagcaacgttctgtcgaaacc
acgctggcgggattggctgacccggccgtcctgagcggcgccttgcaggatcagggggcc
aagctgtccccgtccgggggggacccgctgaccgggccgctggtggtgaccatcggcaag
acggtgaccagccgggcgaagctgaactggtgggagagccgcgcactctacggttggacc
gtgttggtgccgcgcaccaaggaccaggccggcgagatgagcgagcggctgacgtcgtac
ggcgcgttgccggttgaggtgccgaccatcgccgtcgagccgccgcgcagtcccgctcag
atggagcgcgccgttaaggggctggtcgacggtcgtttccaatgggtggtgttcacctcc
accaatgcggtgcgcgcggtgtgggagaagtttggcgagttcggtctggatgcccgagcc
ttctccggggtgaagatcgcctgcgtcggcgaggcgaccgccgaccgggtccgtgccttc
gggatcagcccggagctggtgccggccggggaacagtcgtcgctgggtctgctggacgaa
ttcccgccttatgacagcgttttcgatccggtgaaccgtgttttgctgccgcgcgctgac
atcgccaccgaaacgcttgccgagggactgcgcgagcgtggctgggagatcgaggatgtc
accgcttatcggacggtgcgggccgcacccccgccggcggccacccgggaaatgatcaag
acgggcggcttcgacgccgtgtgcttcacctccagctccacggtgcgcaacttggtcggt
attgccggcaaaccgcacgcgcggaccatcatcgcctgcatcgggcccaagaccgccgag
accgccgccgagtttggcttgcgggtggatgtccagcccgaaaccgccgcggttggtccg
ttagttgacgccctggccgaacatgccgctcggctgcgcgccgagggcgcgctgccccca
ccgcgcaagaagagccgcaggcgctag
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