Micromonospora halotolerans: RMN56_14650
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Entry
RMN56_14650 CDS
T09415
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mhaw
Micromonospora halotolerans
Pathway
mhaw00860
Porphyrin metabolism
mhaw01100
Metabolic pathways
mhaw01110
Biosynthesis of secondary metabolites
mhaw01120
Microbial metabolism in diverse environments
mhaw01240
Biosynthesis of cofactors
Module
mhaw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mhaw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mhaw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RMN56_14650
Enzymes [BR:
mhaw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RMN56_14650
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RMN56_14650
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
WNM42494
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Position
3066750..3068330
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AA seq
526 aa
AA seq
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MTRTRKPVGRIAFVGAGPGDPGLLTRRALDALVDADQVVYDRGVPESLLEHVRAQARSDA
EFSPAEGVPGDVAKVLISAARSGQNAVHLVAGDPFGHDSVVKEVQAVARTAAHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVTTLDFDALAAAVGRGSLAVAVDAGDLAAIRDGLL
AAGVDGATPVAVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAGVSERDKLSWWE
NRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATAEAVRAFGIQPELIPSGEQ
SSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgtaggccggatcgcgttcgtcggggccggtcccggcgac
ccgggcctgctgacccgccgggcgctggacgccctggtcgacgccgaccaggtggtgtac
gaccggggagtccccgagtcgctgctcgaacacgtccgcgcccaggccaggtccgacgcc
gagttcagccccgccgagggcgtgccgggggacgtggcgaaggtgctgatctccgcggcc
cggtccggccagaacgccgtgcacctggtcgccggtgacccgttcggccacgactcggtg
gtcaaggaggtgcaggcggtggcgcgtaccgccgcgcacttcgaggtggtgccgggcgtc
ggccaggccgagggcgtggccacctacgccggcgtgccgctgcccggtgtgcgtaccgcc
gccgacgtcgaggacgtcaccacgctggacttcgacgcgctggccgccgccgtgggccgg
ggctccctggccgtcgccgtggacgccggtgacctggccgccatccgggacggcctgctg
gccgccggggtggacggcgccacccccgtcgcggtgaccggcgacggcaccggcgagacg
cagtacaccaccacgtcgaccgtggactccttcgtggcggcggcgctcggcttcaccggc
cgggtcgtgctcaccgtcggcgcgggcgtctccgagcgcgacaagctgagctggtgggag
aaccggccgctgtacggctggaaggtgctcgtcccccgcaccaaggagcaggccggcgcc
atgagcgcgcggctgcgcgcgtacggggccatcccgtgcgaggtgccgaccatcgcggtc
gagccgccgcgcaccccggcccagatggagcgggcggtcaagggcctggtcgacggccgg
tacgcctgggtgatcttcacttcggtgaacgcggtccgggcggtctgggagaagttcgcc
gagcacggcctggacgcccgccacttcggcggcgtcaagatcgcctgcatcggcgaggcc
accgccgaggcggtccgcgccttcggtatccagccggagctgatcccctcgggggagcag
tcctccgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccggtcggc
cgggtgctgctgccgcgcgccgacatcgccaccgagaccctggccgccgggctcaccgag
cggggctgggaggtcgacgacgtgaccgcgtaccggaccgtccgggccgcgccgccgccc
gccgagatccgcgacgcgatcaagtcgggcgggttcgacgcggtgctcttcacctcgtcc
tcgaccgtccggaacctggtcggcatcgccgggaagccgcacgcgcgtacggttgttgcg
gttatcgggcccaagacggcggagaccgccacggagttcggcctgcgggtcgacgtgcag
ccgccgcacgcctcggtgcccgacctggtggaggcgctcgccgcctacgccgtcgagctg
cgcgagaagctcgccgccatgccggcgaagcagcgccgcggctcgaaggtgcagggcccg
accgccctgaggttccgctga
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