Micromonospora sp. B006: MicB006_4650
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Entry
MicB006_4650 CDS
T05583
Name
(GenBank) uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
micb
Micromonospora sp. B006
Pathway
micb00860
Porphyrin metabolism
micb01100
Metabolic pathways
micb01110
Biosynthesis of secondary metabolites
micb01120
Microbial metabolism in diverse environments
micb01240
Biosynthesis of cofactors
Module
micb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
micb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
micb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MicB006_4650
Enzymes [BR:
micb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MicB006_4650
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MicB006_4650
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AXO36913
UniProt:
A0A385AYH0
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Position
complement(5141431..5143011)
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AA seq
526 aa
AA seq
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MTRTRKPVGQIAFVGAGPGDPGLLTRRALDALVEADQVVYDRGVPESLLAHVRAQARPDA
EFSPAEGVPGDVAKVLISAARAGQNAVHLVSGDPFGHDSVVKEVQAVARTAAHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVTALDFDALATAVGRGSLALAVDAGDLAAVRDGLL
AAGVDGTTAVGVTGDGTGETQYTTTSSVDSFVAAALGFTGRVVLTVGAAVTDRDKLSWWE
NRPLYGWKVLVPRTKEQAGVMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGDATAEAVRAFGIQPELIPSGEQ
SSEGLLAEFSPHDEVLDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgtaggccagatcgctttcgtcggggcgggccccggcgac
cccggcctgctgacccgccgggcgctggacgccctggtcgaggccgaccaggtggtctac
gaccggggcgtacccgagtcgctcctggcgcacgtccgcgcccaggcccggcccgacgct
gagttcagccccgccgagggtgtaccgggggacgtggcgaaggtgctgatctccgcggcc
cgggccgggcagaacgccgtgcacctggtctccggtgacccgttcggccacgactcggtg
gtcaaggaggtgcaggcggtcgcgcgtaccgccgcccacttcgaggtggtgccgggcgtc
ggccaggccgagggcgtcgccacctacgcgggcgtcccgctgccgggcgtacgcaccgcc
gccgacgtcgaggacgtcaccgcgctcgacttcgacgcgctcgccaccgcggtcggccgg
ggttcgctggcgctcgccgtggacgccggtgacctggccgccgtccgggacggtctgctg
gccgccggggtcgacggcaccacagcggtcggggtgaccggcgacggcaccggcgagacg
cagtacaccaccacgtcgagcgtcgactccttcgtcgcggcggcgctcggcttcaccggc
cgggtggtgctcaccgtcggcgcggccgtcaccgaccgcgacaagctgagctggtgggag
aaccgcccgctgtacggctggaaggtgctggtgccccgcaccaaggagcaggccggcgtg
atgagcgcgcggctgcgcgcgtacggggcgatcccgtgcgaggtcccgaccatcgcggtc
gagccgccgcgtaccccggcgcagatggagcgggcggtaaagggcctggtcgacggccgg
tacgcctgggtcatcttcacctcggtcaacgcggtccgggcggtgtgggagaagttcgcc
gagcacggcctcgacgcccgccacttcggcggcgtcaagatcgcctgtatcggggacgcc
accgccgaggcggtccgcgccttcggcatccagccggagctgatcccctccggggagcag
tcctccgagggcctgctggccgagttctcgccgcacgacgaggtcctcgacccggtcggc
cgggtgctgctgccgcgcgccgacatcgcgaccgagaccctggccgccgggctcaccgag
cggggctgggaggtcgatgacgtgaccgcgtaccggacggtgcgggcggcgccgccgccg
gccgagatccgcgacgcgatcaagtcgggcgggttcgacgcggtgctgttcacctcgtcg
tccacggtgcggaacctcgtcggtatcgccgggaagccgcacgcgcgcacggttgttgca
gtcatcgggcccaagacggcggagaccgccaccgagttcggcctgcgggtcgacgtgcag
ccgccgcacgcctcggtgcccgacctggtggaggcgctcgccgcctacgccgtcgagctg
cgggagaagctcgccgccatgccggcgaagcagcgccggggctccaaggtgcagggcccg
accgccctgaggttccgctga
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