Micromonospora sp. HM134: FJK98_07020
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Entry
FJK98_07020 CDS
T06145
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00290
Valine, leucine and isoleucine biosynthesis
mich00660
C5-Branched dibasic acid metabolism
mich01100
Metabolic pathways
mich01110
Biosynthesis of secondary metabolites
mich01210
2-Oxocarboxylic acid metabolism
mich01230
Biosynthesis of amino acids
Module
mich_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FJK98_07020 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FJK98_07020 (leuC)
Enzymes [BR:
mich01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
FJK98_07020 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
FJK98_07020 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QDY06953
UniProt:
A0A518WCI3
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Position
1507006..1508448
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AA seq
480 aa
AA seq
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MVGVTQPRTLAEKVWDAHVVRTAAGEPDLLYIDLHLLHEVTSPQAFDGLRLAGRQVRRPD
LTLATEDHNTPTGYDDPAFRLRRGDLLTIADPTSRTQIETLRRNCAEFGLRLHPLGDENQ
GIVHVIGPQLGVTQPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLPQARPKT
MAVNVTGQLGPGVTAKDLVLALIAQVGTGGGRGHIVEYRGEAIRALSMEGRMTVANMSIE
WGAKAGLIAPDETTFAYLKGRPHAPAGADWDAALAYWRTLPTDDGATFDAEVTLDASRIT
PFVTWGTNPGQGAPLGAAVPDPEDFTTDAERTAARRALEYMDLTPGTPLRDLAVDVVFVG
SCTNGRLEDLRAAADVLRGHRVADGVRMLVVPGSAAVREAAEAEGLDKVFADAGAEWRFA
GCSMCLGMNPDTLKPGERSASTSNRNFEGRQGRGGRTHLVSPPVAAATAVTGRLAAPADL
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atggtgggagtcactcaaccgaggaccctggccgagaaggtctgggacgcgcacgtcgta
cggaccgccgcgggcgagccggacctgctctacatcgacctgcacctgctgcacgaggtg
accagcccgcaggcgttcgacgggctgcgcctggccggccggcaggtccgtcgccccgat
ctcacgctcgcgaccgaggaccacaacaccccgaccgggtacgacgatcccgcgttccgg
ctgcgccggggcgacctgctgacgatcgcggacccgacctcgcgtacccagatcgagacg
ttgcgccgcaactgtgccgagttcggcctgcggctgcaccccctgggcgacgagaaccag
ggcatcgtgcacgtgatcggcccccagctgggcgtcacccagcccggcatgacgatcgtc
tgtggcgattcgcacaccgccacccacggcgcgttcggggcgctggccttcggcatcggc
accagtgaggtcgaacacgtcctggccacccagaccctgccgcaggcccgcccgaagacc
atggcggtcaacgtcaccggccagctcggccccggcgtcaccgccaaggacctggtcctc
gcgctgatcgcccaggtgggcacgggcggcggacgcggccacatcgtggagtaccggggc
gaggccatccgggcgctgtccatggagggccggatgacggtggcgaacatgtccatcgag
tggggcgccaaggcgggcctgatcgcgccggacgagaccaccttcgcgtacctcaagggc
cggccgcacgcgccggccggggccgactgggacgcggcgctggcctactggcggacgctg
cccaccgacgacggcgcgaccttcgacgccgaggtgaccctggacgcctcccggatcacc
ccgttcgtcacctggggcaccaaccccggccagggcgccccgctcggcgcggccgtgccg
gacccggaggacttcaccaccgacgccgagcggaccgccgcgcgccgggccctggagtac
atggacctgaccccgggcaccccgctgcgtgacctcgccgtcgacgtggtgttcgtcggt
tcctgcaccaacggccggctggaggacctgcgggccgccgccgacgtgctgcgcggccac
cgggtcgccgacggggtacggatgctggtggtgcccggctccgccgccgtgcgggaggcc
gccgaggcggagggcctggacaaggtcttcgccgacgccggagcggagtggcggttcgcc
ggctgctcgatgtgcctgggcatgaacccggacacgctgaagccgggcgagcgttcggcc
tcgacctccaaccgcaacttcgagggccggcagggccggggcgggcgtacccacctggtg
tcgccgccggtcgccgccgccaccgccgtgaccggccggctcgccgccccggccgatctg
tag
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