Mycobacterium intracellulare subsp. intracellulare: MIP_06872
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Entry
MIP_06872 CDS
T02325
Name
(GenBank) Porphyrin biosynthesis protein hemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mid
Mycobacterium intracellulare subsp. intracellulare
Pathway
mid00860
Porphyrin metabolism
mid01100
Metabolic pathways
mid01110
Biosynthesis of secondary metabolites
mid01120
Microbial metabolism in diverse environments
mid01240
Biosynthesis of cofactors
Module
mid_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mid_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mid00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MIP_06872
Enzymes [BR:
mid01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MIP_06872
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MIP_06872
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AFS16620
UniProt:
J9WHY3
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Position
complement(4949153..4950808)
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AA seq
551 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTTRAATVLTNAALVFTDPDVPEPVLALIGKDLPP
VSGPAPADPAASSGEGADQGQTQPAVISGGPDIRPALGDPAEVAKTLTHEARTGVDVVRL
VAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPTNAVPTYAGLPLGSSHTVADVRGDVDW
EALAAAPGPLILQATSSHLADAARTLIEHELAENTPCVVTAQGTTCQQRSIETTLHGLTD
SAVLGGTDPAGPLTGPLVVTIGKTVSSRAKLNWWESRALYGWTVLVPRTKDQAGEMSERL
TSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGLD
ARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSVFDPVNRVLLP
RADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTVRN
LVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAEGA
LPPPRKKSRRR
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgtaagccgacacccggccgcatcacgtacgtgggctccggcccc
ggtgacccgggactgttgacgacccgggccgcgacggtgctgacgaacgccgctctggtg
ttcaccgaccctgacgtgcccgagccggtgctggcgctgatcggcaaagacctgccgccg
gtttccggcccggccccggccgacccggccgcctccagcggcgagggcgccgaccagggc
cagacgcagcccgcggtgatctccggtggccccgacatccgcccggcgctgggtgacccc
gccgaggtggccaagaccctgacccacgaggcgcggacgggcgtcgacgtggtccgcctg
gtggccggtgacccgctgacggtcgacgccgtcatcaccgaggtcaacgccatcgcgcgg
agccacctgcacatcgagatcgtgccggggctggcgcccaccaacgccgtcccgacgtac
gcggggttgccgctgggctcctcgcacacggtggccgacgtgcgcggcgacgtggactgg
gaggcgttggccgcggcgccgggaccgctgatcctgcaggccacgtcgtcgcatctggcc
gacgcggcgcgcaccctgatcgaacacgagctcgccgagaacacgccgtgcgtggtgacc
gcgcagggcaccacctgccagcagcgttccatcgagacgacgctgcacggcctgaccgac
tcggccgtgctgggcggcaccgacccggcgggccccctgacgggtccgctggtggtgacc
atcggcaagacggtgtcgagccgggcgaagctgaactggtgggagagccgcgccctgtac
ggctggaccgtgctggtgccccgcaccaaggaccaggccggcgaaatgagcgagcggctg
acgtcctacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccacgcagc
cccgcgcagatggaacgggccgtcaagggattggtcgacggccgcttccagtgggtggtg
ttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcgggctggac
gcgcgcgcgttctccggggtgaagatcgcctgcgtgggcgagtcgaccgccgaccgggtc
cgggcgttcgggatcagccccgagctggtgccggccggtgagcagtcctcgctgggtctg
ctcgacgacttcccgccctacgacagcgttttcgatccggtaaaccgggtcttgctgccg
cgggccgacatcgccaccgagacgctggccgagggcctgcgcgaacgtggttgggagatc
gaggatgtcaccgcctaccggacggtgcgggccgcgccgccgccggcggagacgcgggag
atgatcaagaccggcgggttcgacgcggtgtgcttcacgtccagctcgacggtgcgcaac
ctggtcggtatcgccggcaagccgcacgcgcggacgatcatcgcctgcatcggccccaag
accgccgagaccgccgccgagttcggtctgcgggtcgatgtccagcccgagaccgccgcg
gttggtccgctggtcgacgctttggccgaacacgccgcgcggttgcgcgccgagggcgcg
ctgccaccgccgcgcaaaaagagccgcaggcgctag
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