Mycobacterium sp. KMS: Mkms_0691
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Entry
Mkms_0691 CDS
T00442
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mkm
Mycobacterium sp. KMS
Pathway
mkm00860
Porphyrin metabolism
mkm01100
Metabolic pathways
mkm01110
Biosynthesis of secondary metabolites
mkm01120
Microbial metabolism in diverse environments
mkm01240
Biosynthesis of cofactors
Module
mkm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mkm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mkm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Mkms_0691
Enzymes [BR:
mkm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Mkms_0691
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Mkms_0691
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ABL89907
UniProt:
A1UAP9
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Position
743321..744985
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AA seq
554 aa
AA seq
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MTRQESGRGRKMKPGRITFVGSGPGDPGLLTARAHSVLVNAALVFTDPDVPEAVLSLVGA
HLPPPSGPEPAEPADAADEQAGSTIPGGPDIRPALGDPAEVAKVLAGEAKHGVDVVRLVA
GDPLSVDAVIAEVNALAKSHANFEIVPGLPNTTAVPTYAGLPLGSTHTVADVRDPNVDWA
ALAAAPGPLILHATASHLPDAARTLIEYGLAETTPAVVTANGTTCQQRSVESTLSGLLDK
AALTAPDATGAPAAPLAGPLVVTLGRTVTNRARLNWWESRALYGWTVLVPRTKDQAGEMS
DKLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEF
GLDARAFSGVKIACVGQATAERVRAFGINPELVPTGEQSSLGLLDEFPPYDDIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPASTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALAEHAARLRA
EGALPPPRKKSRRR
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgactcggcaggagagcgggcgtgggcgcaagatgaagcccggccgcatcaccttcgtg
ggctcgggcccgggcgaccccggcctgttgaccgcacgggcccacagtgtgctcgtcaat
gccgcgctggtcttcaccgaccccgacgtccccgaggcggtgctgtccctggtgggcgcg
cacctgcccccaccgtcgggccctgaaccggccgagccggcggacgccgccgacgagcag
gcgggctcgaccatccccggcggcccggacatccggcccgcgctgggcgatccggccgag
gtggccaaggtcctggccggtgaggccaagcacggtgtggacgtggttcggctggtggcc
ggcgacccgctgtcggtcgacgccgtcatcgccgaggtgaacgcgctggccaagagccac
gccaacttcgagatcgtgcccggcctgccgaacaccaccgcggtcccgacgtacgccggc
ctgccgctgggttccacccacaccgtcgccgatgtgcgcgacccgaacgtggactgggcg
gccctggccgccgcgcccggcccgctgatcctgcacgcgaccgcctcgcatctgcccgac
gccgcgcgcacgctgatcgagtacggcctggccgagaccaccccggcggtggtcaccgcc
aacggcaccacctgccagcagcgctcggtcgagtcgacgctgtccgggctgctcgacaag
gccgcgctgaccgcaccggacgcgaccggtgcacccgccgcaccgctggccggcccgctg
gtcgtgacgctcggccgcaccgtcaccaaccgggcccgcctgaactggtgggagagccgc
gcactgtacggctggacggtgctggtgccgcggaccaaggatcaggccggggagatgagc
gacaagctcgtcggccacggcgccctgccgatcgaggtgcccaccatcgccgtcgaaccg
ccgcgcagccccgcgcagatggagcgtgcggtcaagggtctggtcgacggccggttccag
tgggtcgtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcaacgagttc
gggctcgacgcccgcgcgttctccggtgtgaagatcgcctgcgtcggtcaggcgacggca
gagcgggtgcgcgcgttcgggatcaaccccgagctggttccgacgggggagcagtcctcg
ctgggtctgctcgacgagttcccgccgtacgacgacattttcgatccggtgaaccgggtg
ctgctgccgcgcgccgacatcgccaccgagacgctggccgaggggctgcgcgaacgcggt
tgggagatcgaggacgtcaccgcctaccggacggtgcgtgccgcaccgccgccggcctcg
acgcgcgagatgatcaagacgggcggcttcgacgcggtgtgcttcacgtcgagctcgacg
gtgcgcaacctggtcggcatcgccggtaagccgcacgcccgcacgatcgtcgcctgcatc
gggcccaagaccgcggagacggcagcggagttcggcctgcgcgtcgacgtgcagcccgag
gtggccgcggtcggtccgctggtggaggcgctcgccgagcacgccgcccgactgcgcgcc
gagggtgcgctgccgccgccgcgcaagaagagtcgccgccgctga
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