Mycobacterium kansasii ATCC 12478: MKAN_18495
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Entry
MKAN_18495 CDS
T02887
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mkn
Mycobacterium kansasii ATCC 12478
Pathway
mkn00860
Porphyrin metabolism
mkn01100
Metabolic pathways
mkn01110
Biosynthesis of secondary metabolites
mkn01120
Microbial metabolism in diverse environments
mkn01240
Biosynthesis of cofactors
Module
mkn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mkn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mkn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MKAN_18495
Enzymes [BR:
mkn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MKAN_18495
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MKAN_18495
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AGZ52053
UniProt:
U5WS85
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Position
4047579..4049252
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AA seq
557 aa
AA seq
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MMTRGRKPTPGRITFVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPEPVLALIGKDLPP
VSGPAPAAAHAGENVGVAAGESAPSAPAVVSSGPDIRPALGEPADVAKTLTAEARSGADV
VRLVAGDPLSVDAVITEVNAVARTHLHFEVVPGLAATSAVPTYAGLPLGSSHTVADVRGE
LDDTDWDALAAAPGPLILQATASHLADAARTLLDHELADTTPCVVTAHGTTCQQRSVETT
LQGLTDPAILGGADPAGPFAGPLVVTIGKTVSNRGKLNWWESRALYGWTVLVPRTKDQAG
EMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKF
GEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSMGLLDEFPPYDSIFDPV
NRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTS
SSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAAR
LRAEGALPPPRKKSRRR
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgcgagggcgtaagccgactccgggccgcatcactttcgtgggttctggtccc
ggcgacccgggtctgctgaccacacgggctgccgcggtgttggcgaacgccgctctggtg
ttcaccgaccccgatgtacccgaaccggtgctggcgctgatcggcaaggacctgccaccg
gtatccgggccggcgccggctgccgcccatgcgggggagaacgtcggcgtggctgcggga
gagtccgccccgagcgccccggcggtagtctcgagcggccccgacatccgcccggcgctg
ggcgaacccgccgatgtggccaagacgctgaccgccgaggcccgttcgggtgccgacgtg
gtgcggctggtggccggcgacccgttgtcggtggacgcggtgatcaccgaggtgaacgcc
gtggcacgcacccacctgcacttcgaggtcgtgcccgggctggccgccaccagcgcggtc
ccgacctatgccgggctgccgctgggctcctcgcacacggtggccgacgtgcgcggcgaa
ctcgatgacaccgactgggacgcgctggccgccgcccccggaccgctgatcctgcaggcg
accgcgtcgcatctggccgacgccgcacgcaccctgctcgaccacgagctggccgacacg
acaccgtgcgtggtcaccgcgcacggcaccacctgccagcagcgctccgtcgaaaccacg
ctgcagggactgaccgatccggccatcctgggcggcgccgaccccgctggcccgttcgcc
gggccgctggtggtgaccatcggcaagaccgtgagcaaccggggcaagctgaactggtgg
gagagccgggcgctgtacggctggacggtgctggtgccccgcaccaaggaccaggccggc
gagatgagcgagcggttgacgtcctacggggcgctgccggtcgaggtgccgaccattgcc
gtcgaaccgccgcgcagccccgcgcagatggaacgcgccgtcaagggcctggttgatggc
cggttccaatgggtggtgttcacctcgaccaacgcggtgcgggccgtctgggagaaattc
ggcgaattcggtctggatgcgcgggcgttctccggggtcaagatcgcttgtgtcggcgag
tcgaccgccgaccgggttcgtgccttcgggatcagtcccgagctggtgccgtccggcgag
cagtcgtcgatgggtctgctcgacgaattcccgccgtatgacagcattttcgacccggtc
aaccgggtcctgctgccgcgcgccgacatcgccaccgaaacgctggccgagggactgcgc
gaacgtggctgggaaatcgaggacgtcaccgcctaccggaccgtgcgggccgcgccgccg
ccggcggccacccgcgaaatgatcaagacgggcggtttcgacgcggtgtgcttcacctcg
agttccaccgtgcgcaacctggtcggcattgccggtaagccgcacgcgcgcaccatcatc
gcctgcatcggccccaagacggccgagaccgccgccgaattcgggcttcgggtggatgtt
cagccggagaccgccgccgtgggtccactggtggacgccctggccgagcatgccgccaga
ttgcgcgccgagggggcgctgccgccgccacgcaagaagagccgcaggcgctag
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