Mycobacterium lacus: MLAC_29210
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Entry
MLAC_29210 CDS
T07377
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mlj
Mycobacterium lacus
Pathway
mlj00290
Valine, leucine and isoleucine biosynthesis
mlj00660
C5-Branched dibasic acid metabolism
mlj01100
Metabolic pathways
mlj01110
Biosynthesis of secondary metabolites
mlj01210
2-Oxocarboxylic acid metabolism
mlj01230
Biosynthesis of amino acids
Module
mlj_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mlj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MLAC_29210 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MLAC_29210 (leuC)
Enzymes [BR:
mlj01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MLAC_29210 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MLAC_29210 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBX97627
UniProt:
A0A7I7NQ36
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Position
complement(3134875..3136446)
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AA seq
523 aa
AA seq
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MQYTHGFVEDADTAMLSHKEILASRILRAHRRAAIKRIEANFVMAQTAHGAGKPRTLAEK
VWDDHVVVSGAGSQQGGAPDLIYIDLHLVHEVTSPQAFDGLRLNGRRVRRPDLTIATEDH
NVPTVDIDKPIVDPVSRTQVETLRRNCAEFGVRLHPMGDVEQGIVHVVGPQLGLTQPGMT
IVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVTVDGCLPAGVTAKDI
ILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYEFL
RGRPHAPTGAQWDAALAYWQQLRSDDGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAA
VPDPELMTDDAERQAAEKALAYMDLRPGVPMRDIAVDAVFVGSCTNGRIEDLRVVADVLR
GRTVAPGVRMLIVPGSMRVRAQAEAEGLGEIFVAAGAQWRQAGCSMCLGMNPDQLSPGER
CASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLN
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
gtgcagtacacccacggctttgtcgaggacgccgataccgctatgctgtctcacaaagag
atactagcgtctcgcatcctgagagcccatcggcgagccgcaatcaagcgaatcgaggcg
aacttcgtgatggcacagacagctcacggggcgggcaagccgcgcacgctggccgagaag
gtttgggacgaccacgttgtggtatccggtgcgggctcacagcagggtggggcgcccgac
ttgatctacatcgatctgcatttggtgcacgaggtcaccagtccgcaggcctttgacggc
ctgcggctgaatggccgccgagtgcgccggcccgacctcacgatcgccacggaggatcac
aacgtccccaccgtcgacatcgacaagccgatcgtcgacccggtgtcgcgcacccaggtg
gagaccttgcggcgaaactgcgccgaattcggtgtccggctacatccgatgggtgacgtc
gagcagggcatcgtgcatgtcgtcggacctcaattgggactcacccaaccgggtatgacg
atcgtctgcggcgacagccacacctctacccacggcgcgttcggtgcgctggcgatgggc
atcggaacctcggaggtcgagcatgtgctcgccacccagacgctgccgctgcggccgttc
aagacgatggcggtcactgtcgacgggtgcttgcccgcgggtgtgacggccaaagacatc
atcctggcgttgattgccaagatcggaacgggtggcgggcagggccatgtcatcgaatac
cgcggcagcgccatcgaatccctgtcgatggaaggccggatgacgatctgcaacatgagc
atcgaggccggcgcccgagcgggcatggtggccccggacgagaccacctacgagttcttg
cgcggccgtccgcacgcgccgaccggcgcgcagtgggacgcggcactggcgtattggcag
cagttgcgcagcgacgacggcgccgtcttcgataccgaggtctatctggacgcggcttcg
ctgagcccgttcgtcacctggggaaccaaccccggccagggggtgccgttggccgccgcc
gtgccggatcccgaactgatgaccgatgacgccgagcggcaggccgccgagaaagcgttg
gcgtacatggatcttcggcccggggtcccgatgcgggatatcgcggtcgatgcggtgttc
gtggggtcgtgtaccaacggtcgcattgaggatttgcgggtggtggccgacgttttgcgc
ggccggacggtcgccccgggtgttcggatgttgatcgttcccggctcgatgcgggtacgc
gcgcaagccgaagctgagggactcggcgagatttttgtcgccgccggtgcgcagtggcgg
caggcgggatgctcgatgtgccttggcatgaaccccgatcagctttcgccgggtgagcgg
tgtgcgtcgacgtccaaccgcaacttcgaagggcgacagggcaaaggtggccgcacgcat
ttggtgtccccggcggtcgccgcggccaccgcggttcgcggcaccctttccgcccctgcc
gatttgaattga
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