Mycobacterium marinum E11: MMARE11_07940
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Entry
MMARE11_07940 CDS
T04774
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase HemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mmae
Mycobacterium marinum E11
Pathway
mmae00860
Porphyrin metabolism
mmae01100
Metabolic pathways
mmae01110
Biosynthesis of secondary metabolites
mmae01120
Microbial metabolism in diverse environments
mmae01240
Biosynthesis of cofactors
Module
mmae_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmae_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmae00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MMARE11_07940 (hemD)
Enzymes [BR:
mmae01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MMARE11_07940 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MMARE11_07940 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CDM74942
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Position
953348..955024
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AA seq
558 aa
AA seq
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MMTRGRKPRPGRITYVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPESVLALIGNDLPP
VSGPAPATAVADNADAATGGPAEGESDQAVSAVVSSGPDIRPALGDPTEVAKTLTAEARS
GADVVRLVAGDPMSVDAVIAEVNAITRSHLQIEILPGLAATSAVPTYAGLPLGSAHTVAD
VRGDVDWEALAAAPGPLILQATASHLADAARTLVEHELADTTPCVVTAHGTTCQQRSVET
TLQGLTDPAILGGTDPAGPLTGPLVVTIGKTVSNRAKLNWWESRALYGWTVLVPRTKDQA
GEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEK
FGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDEFPPYDSIFDP
VNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFT
SSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAA
RLRAEGALPPPRKKSRRR
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgcgagggcgcaagccgaggccgggccgcattacttatgtgggctctggccca
ggtgacccgggtctgttgaccacacgggccgccgcggtactggcgaacgccgccctggtg
ttcacggaccccgatgtgcctgaatcggtgctggcactgatcggtaacgatctgccgccc
gtctccgggccggcgcccgcgactgcagtggccgacaatgctgacgctgcgaccggcggc
cccgcggagggtgagtccgaccaggcggtctcggcggtggtctctagtggtccggacatc
cgcccggcgctgggtgatcccaccgaagttgccaaaacgctgaccgccgaagcccgttcg
ggcgccgacgtggtgcgtttggtggccggtgacccgatgtcggtggacgcggtgatcgcc
gaggtcaacgccattacccgcagccacctgcagatcgagatcctgcccggtctggcggca
accagcgcggtcccgacctatgcgggactgcccctgggctccgcgcacacggttgccgac
gtgcgtggcgacgtggactgggaggcgctggccgccgcaccgggtccgctgatcctgcag
gccaccgcgtcacatctggctgacgcggcccgcacgctggttgagcacgagctggcggac
acaacgccgtgcgtggtgaccgcgcacggaaccacctgccaacagcgctcggtggaaacc
accctgcaggggctgaccgatccggccatcctgggcggaaccgaccctgccggcccgctg
accgggccgctggtggtgaccatcggcaagaccgtgagcaatcgcgccaagctgaactgg
tgggagagccgggcactgtacggctggaccgtgttggtaccccgaaccaaagaccaggcc
ggcgaaatgagcgagcggctgacgtcctacggtgccctgccggtcgaggtgccgacgatc
gccgtcgaaccgccgcgcagcccggcgcagatggaacgcgcggttaaaggcctcgtcgac
ggccggttccaatgggtcgtgttcacctccaccaacgccgtgcgcgcggtgtgggagaag
ttcggcgagttcggcctggacgcccgggcgttctccggagtgaagatcgcctgtgtgggc
gagtcgactgccgatcgggttcgcgctttcgggatcagcccggagctggtcccggccggg
gaacagtcctcgctgggcctgctggacgaattcccgccctacgacagcattttcgatccg
gtcaaccgggtgttgctgccgcgcgctgacatcgccaccgagacgctggccgaggggctg
cgcgagcgtggctgggagatcgaggacgtgacggcctaccgcacggtgcgggccgctccg
ccgccggcggccacccgcgagatgatcaagacgggcggtttcgacgcggtctgcttcacc
tcgagttctacggtgcgcaatctggtcggtatcgccggtaagccgcacgcgcggaccatc
atcgcctgcatcggacccaagaccgccgaaacggccgccgagttcgggctccgggtggat
gtccaacccgagaccgccgcggtgggcccgctggtggacgcgctggccgagcacgccgcc
cggctgcgcgccgaaggagccctgcccccgcctcgcaagaagagtcgccggcgctag
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