Methylococcus mesophilus: OOT43_05940
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Entry
OOT43_05940 CDS
T09468
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mmeo
Methylococcus mesophilus
Pathway
mmeo00290
Valine, leucine and isoleucine biosynthesis
mmeo00660
C5-Branched dibasic acid metabolism
mmeo01100
Metabolic pathways
mmeo01110
Biosynthesis of secondary metabolites
mmeo01210
2-Oxocarboxylic acid metabolism
mmeo01230
Biosynthesis of amino acids
Module
mmeo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmeo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
OOT43_05940 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OOT43_05940 (leuC)
Enzymes [BR:
mmeo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
OOT43_05940 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
OOT43_05940 (leuC)
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
UZR30183
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Position
complement(1320400..1321806)
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AA seq
468 aa
AA seq
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MSGKTLYDKLWDDHVVHADADGSCLIYIDRHLIHEVTSPQAFEGLRMAGREPWRLDANLA
VADHNVPTADRDRGIADPVSRLQVETLDKNCADFGITEFAMDDLRQGIVHVIGPEQGATL
PGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLVQRKAKNMLVRVDGKLAPGVT
AKDLVLAVIGRIGTAGGTGYTIEFAGEAIRGLSMEGRMTVCNMAIEAGARAGLVAVDEVT
FDYLKGRPFAPAGALWDQAVDAWHKLHSDPDAVFDKTVEIDAASIKPQVTWGTSPEQVVS
VDAKVPDPAVETDPVRRESMERALQYMDLQPGTPIEAIRVDRVFIGSCTNARIEDLRAAA
EVARGHKVAVKQALVVPGSGLVKRQAEQEGLDKVFTDAGFEWREPGCSMCLAMNADRLEP
GERCASTSNRNFEGRQGYGSRTHLVSPAMAAAAAIHGHFVDITEGRRA
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgagcggaaaaaccctttacgacaaactgtgggacgaccacgtcgtgcatgccgatgcg
gacggatcgtgcctgatctatatcgaccgccatctgattcacgaggtgacctcgccccag
gctttcgaggggctgcggatggcggggcgcgaaccgtggcggctggatgccaaccttgcg
gtggccgaccacaacgtgccgaccgccgaccgcgaccggggcatcgccgatccggtatcg
cgtctgcaggtggaaaccctggataagaactgcgccgatttcggcatcaccgaattcgcg
atggacgacctgcgccagggcatcgtgcacgtgatcggtcccgagcagggcgcgaccctg
ccaggcatgaccatcgtttgcggcgattcgcatacgtctacccacggtgccttcggggcg
ctcgccttcgggatcggcacttccgaggtcgagcacgtgctggccacacaatgcctggtg
cagcgcaaggcgaagaacatgctggtgcgcgttgacggcaagctggcgccgggcgtgacg
gcgaaagacctcgtgctggcggtcatcgggcgtatcggaaccgccggcggcaccggctat
accatcgaattcgccggcgaggccatccgcggcttgtcgatggaaggccggatgacggtc
tgcaacatggctatcgaggcgggcgcacgcgccggcctggtggcggtggacgaggtgacg
ttcgactacctcaagggccggccgttcgctccggcaggcgcgctgtgggatcaggcggtc
gatgcctggcacaaactgcacagcgatcccgatgcggtgttcgacaagaccgtcgagatc
gacgcggccagcatcaagccacaggtgacctggggaacctcgccggagcaggtcgtatcg
gtggatgccaaggtacccgacccggcggtggaaacggatcccgtgcggcgcgaaagcatg
gagcgggcgctgcagtacatggatctccagccgggcacgccgatcgaggcgatccgggtc
gaccgggtgttcatcggctcctgcaccaacgcgcggatcgaggacctgcgcgcggcggcg
gaagtcgctcgtggccataaggtcgccgtcaagcaggcgctggtggtgccgggttccggt
ctggtcaagcgccaggcggagcaggaggggctggacaaggttttcaccgatgccggattc
gaatggcgtgagcccggctgttccatgtgcctggcgatgaacgccgaccggctggaaccc
ggtgagcgttgcgcctcgacctccaaccggaatttcgaggggcgccagggctatgggagc
cgtacgcatctggtgagtccggccatggcggctgcggcggccattcacggccatttcgtc
gacatcaccgaaggacggcgtgcatga
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