Mycolicibacter minnesotensis: MMIN_22170
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Entry
MMIN_22170 CDS
T06638
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mmin
Mycolicibacter minnesotensis
Pathway
mmin00860
Porphyrin metabolism
mmin01100
Metabolic pathways
mmin01110
Biosynthesis of secondary metabolites
mmin01120
Microbial metabolism in diverse environments
mmin01240
Biosynthesis of cofactors
Module
mmin_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmin_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmin00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MMIN_22170 (hemD)
Enzymes [BR:
mmin01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MMIN_22170 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MMIN_22170 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BBY34156
UniProt:
A0A7I7R7P8
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Position
2370774..2372474
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AA seq
566 aa
AA seq
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MSVRGQKPKPGRIVFVGSGPGDPGLLTTRARTALTNAALVFVDPDVPEAVLALVGLDLPP
IVGPVPPAPKTDKSDDAADGTDAADDAVGSAPATVPGGPDIRPALGEPAEVAKILAAEAR
SGADVVRLVAGDPLSIDAVITEVNAVARTSIAFEIVPGLPATSAVPTYAGLPLGSSHTVA
DVRDPQVDWAALAAAPGPLILQATTSHLPEAARTLIEYGLSDNTPCVVTTSGTTCAQRSI
ESSLGGLTDAAALAGIDPVILPNGQETSAGPLVVTIGKTVTSRAKLNWWESRALYGWTVL
VPRTKDQAAEMSDRLVGHGASPIEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTN
AVRAVWEKFAEFGLDARAFSGVKIACVGEATAERVRAFGISPELVPSGEQSSLGLLDEFP
PYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPANIREMIKTG
GFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAAEFGLRVDVQPETAAVGPLV
DALAEHAARLRAEGALPPPRKKSRRR
NT seq
1701 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgtgcgtgggcagaagcccaagccggggcgcattgtgttcgtcggctcggggcct
ggtgacccgggtctgctgacgacacgggcgcggacggccctgacgaatgccgcgctggtg
ttcgtcgaccccgacgtgcccgaggcggtgctggcgctggtaggtctggacctgccgccg
atcgtggggccggtgcccccggctcccaagacggacaaatccgatgacgcggccgacggc
accgatgccgctgacgacgcggtcggcagcgctcccgcgaccgttccgggtggccccgac
atccgccccgcgctgggcgagccggccgaggtcgccaagatcctggctgccgaggcgcgt
tccggcgccgatgtcgtgcgcttggtagccggtgacccgctgtcgatcgacgcggtcatc
accgaggtgaacgcggtggcccgcaccagcattgcgttcgagatcgtgccgggactgccg
gccaccagcgcggtgcccacctacgcaggtctgccgctcgggtcttcgcacactgttgct
gacgttcgtgacccgcaggtggactgggccgccttggctgctgctccgggtccgctgatc
ctgcaggccaccacctcgcaccttcctgaggcggctcgcaccctgatcgaatacggcctg
tcggacaacaccccgtgtgtggtcaccacgtcgggcaccacttgtgctcagcggtcgatc
gagtccagcctcggcggcctgaccgacgctgcggcgctggccggtatcgacccggtgatc
ctgcccaacggccaggagacgtcggctggtccgctcgtggtcaccatcggcaagacggtg
accagccgcgccaagctgaactggtgggagagtcgcgccctgtacggctggaccgttctg
gtgccgcgcaccaaggaccaggccgccgaaatgagcgaccggttggtcgggcacggcgcc
tcgccgatcgaggttccgaccatcgcggtggagccgcctcgcagcccggcccagatggaa
agggccgtcaagggtttggtggacggtcgctaccagtgggtggtgttcacctcgaccaac
gccgtgcgcgccgtgtgggagaagttcgccgaattcggtctggatgctcgcgcgttctcc
ggtgtgaagatcgcctgcgtgggtgaggccaccgcggagcgggttcgggcgttcgggatc
agccctgagctggtgccgtccggcgagcagtcctccctgggcctgctcgacgaattcccg
ccctacgacgacgttttcgacccggtgaatcgggtgctgctgccgcgtgcggacattgcc
accgagacgctggccgaaggcctgcgggaacggggctgggagatcgaggacgtcaccgct
taccgcaccgtgcgggccgctccgccgcccgccaacatccgcgagatgatcaagaccggt
gggttcgacgcggtctgcttcacctccagctcgacggtccgcaacctcgtcggcatcgcc
ggcaagccgcacgcccgcaccctggtggcctgcatcggacccaagaccgctgagacagca
gcagaattcgggctgcgggtagacgtgcagccggagaccgcggcagttggtcccctggtc
gatgcactggccgagcacgcggcgcgactgcgggccgagggtgcgttgccgccaccgcgt
aagaagagccgcaggcgatga
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