Mycobacterium sp. MOTT36Y: W7S_22785
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Entry
W7S_22785 CDS
T02113
Name
(GenBank) uroporphyrin-III C-methyltransferase HemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mmm
Mycobacterium sp. MOTT36Y
Pathway
mmm00860
Porphyrin metabolism
mmm01100
Metabolic pathways
mmm01110
Biosynthesis of secondary metabolites
mmm01120
Microbial metabolism in diverse environments
mmm01240
Biosynthesis of cofactors
Module
mmm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
W7S_22785
Enzymes [BR:
mmm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
W7S_22785
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
W7S_22785
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AFJ37506
UniProt:
I2AJN2
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Position
complement(4967685..4969343)
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AA seq
552 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTTRAAAVLTNAALVFTDPDVPEPVLALIGKDLPP
VSGPAPADPAASSGDGADQGQTQPAVISGGPDIRPALGDPAEVAKTLTHEARTGVDVVRL
VAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPTNAVPTYAGLPLGSSHTVADVRDPNVD
WEALAAAPGPLILQATSSHLADAARTLIEHELAENTPCVVTAQGTTCQQRSIETTLHGLT
DSAVLGGTDPAGPLTGPLVVTIGKTVSSRAKLNWWESRALYGWTVLVPRTKDQAGEMSER
LTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSVFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgtaagccgacacccggccgcatcacgtacgtgggctccggcccc
ggtgacccgggactgttgacgacccgggccgcggcggtgctgacgaacgccgctctggtg
ttcaccgaccctgacgtgcccgagccggtgctggcgctgatcggcaaagacctgccgccg
gtttccggcccggccccggccgacccggccgcctccagcggcgacggcgccgaccagggc
cagacgcagcccgcggtgatctccggtggccccgacatccgcccggcgctgggtgacccc
gccgaggtggccaagaccctgacccacgaggcgcggacgggcgtcgacgtggtccgcctg
gtggccggtgacccgctgacggtcgacgccgtcatcaccgaggtcaacgccatcgcgcgg
agccacctgcacatcgagatcgtgccggggctggcgcccaccaacgccgtcccgacgtac
gcggggctgccgctgggctcctcccacacggtggccgacgtgcgcgaccccaatgtggat
tgggaggctttggccgcggcgccggggccgctgatcctgcaggccacgtcgtcgcatctg
gccgacgcggcgcgcaccctgatcgaacacgagctcgccgagaacacgccgtgcgtggtg
accgcgcagggcaccacctgccagcagcgttccatcgagacgacgctgcacggcctgacc
gactcggccgtgctgggtggaaccgacccggcgggccccctgaccggtccgctggtggtg
accatcggcaagacggtgtcgagccgggcgaagctgaactggtgggagagccgcgccctg
tacggctggaccgtgctggtgccccgcaccaaggaccaggccggcgaaatgagcgagcgg
ctgacgtcctacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccacgc
agccccgcgcagatggaacgggccgtcaagggattggtcgacggccgcttccagtgggtg
gtgttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcgggctg
gacgcgcgcgcgttctccggagtgaagatcgcatgcgtgggcgagtcgaccgccgaccgg
gtccgggcgttcgggatcagccccgagctagtgccggccggtgagcagtcctcgctgggt
ctgctcgacgacttcccgccctacgacagcgttttcgatccggtgaaccgggtcttgctg
ccgcgggccgacatcgccaccgagacgctggccgagggcctgcgcgaacgtggttgggag
atcgaggatgtcaccgcctaccggacggtgcgggccgcgccgccgccggcggagacgcgg
gaaatgatcaagaccggcgggttcgacgcggtgtgcttcacgtccagctcgacggtgcgc
aacctggtcggtatcgccggcaagccgcacgcgcggacgatcatcgcctgcatcggcccc
aagaccgccgagaccgccgccgagttcggtctgcgggtcgatgtccagcccgagaccgcc
gcggttggtccgctggtcgacgctttggccgaacacgccgcgcggttgcgcgccgagggc
gcgctgccaccgccgcgcaaaaagagccgcaggcgctag
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