Marmota marmota marmota (Alpine marmot): 107148396
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Entry
107148396 CDS
T09644
Symbol
Pde8a
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00230
Purine metabolism
mmma01100
Metabolic pathways
mmma04927
Cortisol synthesis and secretion
mmma04934
Cushing syndrome
mmma05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107148396 (Pde8a)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
107148396 (Pde8a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
107148396 (Pde8a)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
107148396 (Pde8a)
Enzymes [BR:
mmma01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
107148396 (Pde8a)
BRITE hierarchy
Motif
Pfam:
PDEase_I
PAS
PAS_9
PAS_4
PAS_3
PAS_8
Sina_ZnF
DUF5894
UBA_E1_SCCH
Motif
Other DBs
NCBI-GeneID:
107148396
NCBI-ProteinID:
XP_015348508
Ensembl:
ENSMMMG00000019109
LinkDB
All DBs
Position
Unknown
AA seq
756 aa
AA seq
DB search
MRFHQDQLQVLLVFTKEDNQCKGFCRACEKAGFKCTVTKEAQTVLDCFLDKHHDIIIIDH
RNPRQLDAEALCRSIRSSKLAENTVIVGVVRRVDREELSVMPLISAGFTRRYIENPSIMA
CYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITSEDHIIQYANPAFETTMGYQS
GELIGKELAEVPINEKKAELLDTINSCIRIGKEWQGTHYTKKKNGDSIQQNVKIIPVIGQ
GGKIRHYVSIIRVCSGNNKAEKIPEGVQSDTHTDNQTGKHKDRRKSSLDIKSVASRSEVN
NQRRHSSLARIHSMTIEAPITKVINIINAAQENSPMPVTEALDRVLEILRTTELYSPQFG
AKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNLQQVSHSIITPISLHDVPSRIARGLE
NVEYWDFDIFELEAATHNRPLIYLGLKIFAHFGICEFLNCSESTLKSWLQIIEANYHSSN
PYHNSTHAADVLHATAYFLYKQRIKESLDPVDEVAALIAATIHDVDHPGRTNSFLCNAGS
ELAILYNDTAVLESHHAALAFQLTVRDDKCNIFKNVERNDYRTLRQNIIDMVLATEMTKH
FEHVNKFVNSVNKPLATLEQDEETEKDQEAVNTMLRAPENRTLIKRMLIKCADVSNPCRP
LEHCIEWAARISEEYFSQTDEEKQQNLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAW
DAFVDLPDLMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatcaagatcaacttcaggtacttttagtgtttaccaaagaagataaccag
tgtaagggattctgcagggcatgtgaaaaagcaggatttaagtgtacagtaaccaaggag
gcacaaacagtccttgactgtttcctggacaaacatcatgacatcatcatcatagaccac
agaaatccccgtcagctggatgcagaggcattgtgcaggtctatcagatcatcaaaactc
gcagaaaacacagttattgttggtgtagtacgcagggtggacagagaagagttgtctgta
atgcccttaatttctgctggctttacaaggaggtatatagaaaaccccagtatcatggcc
tgttacaatgaactgctccagctggaatttggagaggtgcgatcacaactgaaactcagg
gcttgtaactcaatattcactgcattagagaaaagtcaagaagcaattgaaattacaagt
gaagaccacattatacagtatgcaaatcctgcatttgaaacaacaatgggctatcagtca
ggtgaattaatagggaaggagttagcagaagtgcctataaatgaaaaaaaagctgaattg
cttgatactataaattcatgcatcaggataggcaaggagtggcaaggaactcactatacc
aaaaagaaaaatggagatagtatacagcaaaatgtgaagataatacctgtcattggacag
ggaggaaaaattagacactatgtgtccattatcagagtatgcagtggcaacaataaggct
gagaaaataccagaaggtgttcagtctgacactcatacagataatcagacaggcaaacat
aaagacaggaggaaaagctcactcgacattaaatctgttgcctctcgaagtgaagttaac
aaccagagacgacactcctccctggcccggatacattccatgacgatcgaggcacccatc
accaaggtaatcaatatcatcaatgctgcccaggaaaatagtcccatgcctgtgacagaa
gccttggaccgtgtgttagaaattttgagaaccactgagttatattcaccacagttcggt
gctaaggatgatgatcctcatgccaatgacctcgtcgggggcttaatgtctgatggtttg
cgaagattatcggggaatgaatatgttctttcaacaaaaaaccttcaacaggtttcacat
agtataatcactcccatttcccttcacgatgtcccatcgcggatagctcgaggcctggaa
aatgtggaatactgggactttgatatttttgaactggaggctgccacccataatagacct
ttgatttatcttggtctcaaaatatttgctcactttggaatctgtgaattcttaaactgc
tcggagtcaacactgaaatcgtggttacaaattattgaagcaaactatcattcttctaac
ccctaccacaattctacacatgctgctgatgttcttcacgccactgcctattttctatac
aaacagaggataaaggaaagtttagatccagttgatgaggtcgctgctctcatcgcagcc
accattcacgatgtggatcaccctgggaggaccaactccttcttgtgcaatgcagggagc
gagctggccattttgtacaatgacactgctgtgctagagagccatcacgcagccttggcc
ttccagctgactgttagagatgacaaatgcaatatcttcaaaaatgtggagaggaatgac
tatcggacactgcgccagaatattattgacatggtcttagccacagaaatgacaaagcac
ttcgaacatgtcaacaaatttgttaatagtgttaacaagcccttggcaacactagaacaa
gatgaggaaactgaaaaagaccaggaagccgtaaacactatgctcagggctccagagaac
cgcactctgatcaaacgaatgctgattaaatgtgctgatgtgtccaacccctgccggccc
ctggagcactgcattgagtgggctgcacgcatctcagaagaatatttttctcagactgat
gaagagaagcagcagaacttgcctgtggtaatgccggtttttgacagaaacacctgcagc
atccccaaatcccagatctcttttatagattacttcatcacagacatgtttgatgcttgg
gacgcctttgtggaccttcctgacttaatgcagcatcttgacaacaactttaaatactgg
aaaggactggatgaaatgaagcttcggagcctccgacctcctcctgagtag
DBGET
integrated database retrieval system
