Mus musculus (house mouse): 319583
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Entry
319583 CDS
T01002
Symbol
Lig4, 5830471N16Rik, tiny
Name
(RefSeq) ligase IV, DNA, ATP-dependent
KO
K10777
DNA ligase 4 [EC:
6.5.1.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu03450
Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03450 Non-homologous end-joining
319583 (Lig4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
mmu03400
]
319583 (Lig4)
Enzymes [BR:
mmu01000
]
6. Ligases
6.5 Forming phosphoric-ester bonds
6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
6.5.1.1 DNA ligase (ATP)
319583 (Lig4)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
DNA Ligase 4 complex
319583 (Lig4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_ligase_A_M
DNA_ligase_A_N
BRCT
DNA_ligase_IV
DNA_ligase_A_C
BRCT_2
RNA_ligase
mRNA_cap_enzyme
Motif
Other DBs
NCBI-GeneID:
319583
NCBI-ProteinID:
NP_795927
MGI:
1335098
Ensembl:
ENSMUSG00000049717
UniProt:
Q8BTF7
LinkDB
All DBs
Position
8:complement(10020020..10027680)
Genome browser
AA seq
911 aa
AA seq
DB search
MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDV
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGART
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKKKDLVKKSLLQLITQSSA
LEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDISI
TLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGALYRYFSRNGYNYTD
QFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSGL
QTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALND
AIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMM
SHFLCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILC
GTEKPEVYIEPQNSVIVQIKAAEIVPSDMYKTGSTLRFPRIEKIRDDKEWHECMTLGDLE
QLRGKASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFE
DVEFCVMSGLDGYPKADLENRIAEFGGYIVQNPGPDTYCVIAGSENVRVKNIISSDKNDV
VKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLG
IKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGI
TALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKFKILQESWVSDSVDK
GELQEENQYLL
NT seq
2736 nt
NT seq
+upstream
nt +downstream
nt
atggcttcctcacaaacttcacaaactgttgcagctcatgtcccctttgcagacttatgt
tccacactagaacggatacagaaaggtaaagaccgtgcagaaaaaatcaggcacttcaag
gagtttttggattcgtggagaaaatttcatgatgcccttcataagaacagaaaggacgtt
acagactctttttaccctgcaatgagactcattctcccccagttagaaagagagaggatg
gcttatggaatcaaagaaaccatgctcgctaagctctacatcgaattgctgaacttacca
cgagaaggcaaggatgcccagaagctcctcaattaccgaacccccagtggagctcgcacg
gatgctggggactttgccatgattgcatactttgttttgaagccaaggtgcttacagaaa
ggaagcttaaccatacagcaggtaaatgaactcttagacttagttgccagcaataactct
ggcaaaaaaaaagacctagtgaaaaagagccttcttcagttaataacccagagttcagca
ctggagcaaaaatggctgattcgcatgattatcaaagacttaaagcttggcatcagtcag
caaacaatattttccattttccacaatgatgcagttgagttgcacaacgtcaccacagat
ctggaaaaggtctgcaggcagctgcatgacccctctgtagggcttagtgacatctctatc
actctgttttctgcctttaagccaatgctagctgctgtagcagacgtggagcgtgtggag
aaggacatgaagcagcagagtttctacatcgaaactaagcttgatggtgagcgcatgcag
atgcacaaagatggcgcgctgtaccggtacttctccagaaacggttacaactataccgac
cagtttggtgaatctccacaggaaggctctctcaccccatttattcacaatgcgttcggg
acagatgtgcaagcgtgcatccttgacggtgagatgatggcctacaacccaacaacacag
actttcatgcagaagggggtcaagtttgatatcaaaaggatggtggaagattctggccta
cagacttgttactctgtttttgacgtactgatggttaataagaagaagctagggcgcgag
actcttaggaagaggtatgagatccttagtagcactttcacacccatacaaggccgcata
gaaatagtgcagaaaactcaagctcatacaaagaaggaagtagtggatgcattaaatgat
gccatagacaagagagaagaggggatcatggttaaacaccctctgtccatttacaagcca
gacaaaagaggtgaagggtggctaaagattaaaccagagtacgtcagtggactaatggat
gaattagacgtcctaattgtggggggctactggggtaaaggttcacgaggtggcatgatg
tctcactttttgtgtgcagtggcagagacaccacctcctggtgacaggccatctgtattc
cacactctgtgccgtgttgggtctggttacaccatgaaagaactctatgacctgggcttg
aaattggcaaaatactggaagccttttcataagaaatctccaccaagtagcattctgtgt
ggtacagagaagccggaagtgtacatagagcctcagaactctgtcattgttcagatcaag
gcagctgagatcgtccccagtgacatgtacaagactggctccaccctgcgcttcccacgc
atcgaaaagatcagagatgacaaagagtggcacgaatgtatgacactgggtgacttggag
cagctgagggggaaagcatctgggaagcttgccacgaaacaccttcatgtaggtgatgat
gatgaacctagagaaaaaaggcggaagcccatctccaagacgaagaaagccattagaatc
attgaacacttaaaagcacccaacctttctaacgtaaacaaagtttccaatgtatttgaa
gatgttgagttttgtgttatgagtggattagatggttatccaaaggctgacctagagaac
agaattgcagaattcggtggttatatagtacagaatccaggcccggatacatactgtgtt
attgcaggttctgagaacgttagagtgaaaaacattatttcttcagataaaaatgatgtt
gtcaagcccgagtggcttttagagtgttttaagacaaaaacatgcgtgccgtggcaacct
cgctttatgattcacatgtgcccgtcgacaaagcagcattttgcccgtgagtatgactgc
tatggtgatagctattttgttgacacagatttggatcaattgaaagaagtgtttctagga
attaaacccagtgagcagcagactcctgaagaaatggcccctgtgattgctgacttagaa
tgtcgttattcctgggaccactctcctctcagtatgtttcgacattacaccatttatttg
gacttgtatgctgttattaatgacttgagttccagaattgaagccacgagattaggtatt
acagcccttgagctgcggtttcatggagcaaaggtggtttcctgcttatctgaaggggta
tctcatgttatcattggggaggatcagagacgagttactgactttaaaatattcagaaga
atgcttaagaaaaagtttaaaatcctgcaagaaagttgggtgtccgattcagtagacaag
ggcgaactgcaggaggaaaaccagtatttgctttag
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