Microcebus murinus (gray mouse lemur): 105869687 Help Entry 105869687         CDS       T07238                                  Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur04010   MAPK signaling pathway mmur04014   Ras signaling pathway mmur04015   Rap1 signaling pathway mmur04022   cGMP-PKG signaling pathway mmur04066   HIF-1 signaling pathway mmur04068   FoxO signaling pathway mmur04072   Phospholipase D signaling pathway mmur04150   mTOR signaling pathway mmur04151   PI3K-Akt signaling pathway mmur04152   AMPK signaling pathway mmur04211   Longevity regulating pathway mmur04213   Longevity regulating pathway - multiple species mmur04520   Adherens junction mmur04910   Insulin signaling pathway mmur04913   Ovarian steroidogenesis mmur04923   Regulation of lipolysis in adipocytes mmur04930   Type II diabetes mellitus mmur04931   Insulin resistance mmur04932   Non-alcoholic fatty liver disease mmur04960   Aldosterone-regulated sodium reabsorption mmur05010   Alzheimer disease mmur05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105869687    04014 Ras signaling pathway     105869687    04015 Rap1 signaling pathway     105869687    04066 HIF-1 signaling pathway     105869687    04068 FoxO signaling pathway     105869687    04072 Phospholipase D signaling pathway     105869687    04022 cGMP-PKG signaling pathway     105869687    04151 PI3K-Akt signaling pathway     105869687    04152 AMPK signaling pathway     105869687    04150 mTOR signaling pathway     105869687  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     105869687  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105869687    04923 Regulation of lipolysis in adipocytes     105869687    04913 Ovarian steroidogenesis     105869687   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105869687   09149 Aging    04211 Longevity regulating pathway     105869687    04213 Longevity regulating pathway - multiple species     105869687  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105869687   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105869687   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105869687    04932 Non-alcoholic fatty liver disease     105869687    04931 Insulin resistance     105869687  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmur01001]     105869687   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mmur04090]     105869687 Enzymes [BR:mmur01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      105869687 Protein kinases [BR:mmur01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    105869687 CD molecules [BR:mmur04090]  Proteins   105869687 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  105869687 NCBI-ProteinID:  XP_020139639 Ensembl:  ENSMICG00000011978 UniProt:  A0A8B7WWH4 LinkDB All DBs Position 24:complement(14990945..15088806) Genome browser AA seq 1382 aa AA seqDB search MPVHLALPWALLMHPWVHLFLLLTCPALHVFPLLVCPGMDIRNNLTRLHELENCSVIEGH LQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLRGLFPNLTVIRGSRLFFNYA LVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDN EECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC LGNCSEPDDPTKCVACRNFYLEGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQ GCHQYVIHNNKCIPECPSGYTMNSSNLVCTPCLGPCPKVCHILEGEKTIDSVTSAQELRG CTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLHLIRGET LEMGSYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQ ERNDIALKTNGDQASCENELLKFSYIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPY QNVTEFDGQDACGSNSWTVVDVDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTF SDERRTYGAKSDIIYVQTNATNPSVPLDPISVSNSSSQILLKWKPPSDPNGNITHYLVFW ERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDAQKHNQSEYEDAAGECCTCPKTDSQI LKELEESSFRKTFEDYLHNVVFVPRKTSPGTGAEDPRPSRKRRSLGEVGNVTVAAIPTLP TFPNTPSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPDERCSVAA YVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPREPNGLIVLYEVSYRRYGDEELHL CVSRKHYALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATHFYVTDYLDVPSNIAKII IGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEV PREKIALLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVM KGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQ MAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLL PVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQP ENCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELE MEFEDMESVPLDRSCQREEAGSREGGSSLGLKRNYEEHTPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgcccgtgcacttggctctgccctgggctcttctcatgcacccgtgggtgcaccttttc cttctactcacttgtcccgctctgcacgtcttcccccttctagtgtgccccggcatggac atccggaacaacctcaccaggctgcacgagctggagaactgctcggtcattgagggccac ctgcagatactcttgatgttcaagacgaggcccgaggatttccgagacctcagtttcccc aaactcatcatgatcaccgattacttgctgctcttccgggtctacgggttggagagcctc aggggcctgttccccaacctcacggtcatccggggctcccgcctcttcttcaactacgcg ctggtcatcttcgagatggtccacctgaaggagctcgggctgtacagcctcatgaacatc acccgggggtccgtgcgcatcgagaaaaacaacgagctctgctacctggccaccatcgac tggtcccgtatcctggactcggtggaggataattacatcgtgctgaacaaagatgacaac gaagagtgtggggacatctgcccggggaccgccaagggcaagaccaactgccccgccacc gtcatcaacgggcagttcgtggaacggtgctggactcacagtcattgccagaaagtttgc ccaaccatctgtaagtcacacggctgcaccgccgaaggcctttgctgtcacagcgagtgc ctgggcaactgttccgagcccgacgaccccaccaagtgtgtggcctgccgcaacttctac ctggagggcaggtgcgtggagacctgcccacccccctactaccacttccaggactggcgc tgtgtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcgcggaggcag ggctgccaccagtatgtcattcacaacaacaagtgcattccggagtgcccctctggatac acgatgaattccagcaacttggtgtgcacaccgtgcctgggcccctgtcccaaggtctgc cacattctggaaggcgagaagaccatcgactcggtgacatccgcgcaggagctccgagga tgcaccgtggtcaacgggagtcttatcatcaacatccgagggggcaacaacctagcagct gaactagaagccaacctcggcctcattgaagaaatttcagggtatctaaaaatccgtcgc tcctacgcattggtgtcgctttccttcttccggaagttgcatctgattcgaggagagacc ttggaaatggggagctactccttctacgctttggacaaccagaacttaaggcagctctgg gactggagcaaacacaacctcaccatcactcagggcaaactcttcttccactataatccc aaactctgtttgtcagaaattcacaagatggaagaagtctcaggaaccaaagggcgccag gagaggaatgacatcgccctgaagaccaacggggaccaggcgtcctgtgaaaatgaatta cttaaattttcttacattcggacatcttttgacaagatcttgctgaaatgggagccatac tggccccccgacttccgagacctcctgggcttcatgctgttctacaaagaggccccttat cagaacgtgacagagttcgacgggcaggatgcgtgtggctccaacagctggacggtggtg gacgttgacccgcccctgaggtccaatgaccccaagtcacagaaccaccctggctggctg atgcgtggtctcaagccctggactcagtatgccatctttgtcaagaccttggtcaccttc tcagatgaacgccggacctacggggccaagagcgacatcatttatgtccagacgaatgcc accaacccgtccgtccccctggacccgatctccgtttctaattcctcgtcccagatcctt ctgaagtggaagccgccctcggaccccaacggcaacatcacgcactacctggttttctgg gagaggcaggcagaagacagcgagctgttcgagttggattattgcctcaaagggctgaag ctgccctcgcggacctggtcgcccccgttcgagtccgacgacgcgcagaagcacaaccag agcgagtacgaggacgcggcgggcgagtgctgcacctgccccaagacggactcgcagatc ctcaaggagctggaggagtcgtcgttccggaagacgttcgaggattacctgcacaacgtg gtcttcgttcccagaaaaacctctccaggcactggcgctgaggaccctaggccatcccgg aaacgcaggtctcttggcgaagtcgggaacgtgacggtggccgccattcccaccctcccc actttccccaacaccccgtcaacgagcgtccccaccagcccagaggagcaccggccgttc gagaaagtggtgaacaaggagtcgctggtcatctcgggcctgcggcacttcacgggctac cgcatcgagctgcaagcttgcaaccaagatgcccccgacgaacggtgcagcgtggccgcc tacgtcagcgccaggaccatgcctgaagccaaggctgatgacatcgtaggccccgtgacc catgagatcttcgagaacaacgtcgttcacctgatgtggcaggagccgagggaacccaac ggcctgatcgtgctgtatgaagtcagttaccggcgatatggcgatgaggagctgcatctc tgtgtgtcccgcaagcattacgcgctggagcggggctgcaggctgcgcgggctgtcgccg gggaactacagcgtgcgagtccgggccacctccctggcgggcaacggttcctggacagaa gccacccatttttacgtgacggactatctagacgtcccatcaaatattgcaaaaattatc atcggccctctcatctttgtatttctcttcagtgtggtgattggaagtatttacttattc ctgagaaaaaggcagccagacgggccgctgggaccgctgtacgcatcttcaaaccctgag tacctcagtgccagtgatgtgtttccgtgttctgtgtacgtgccggacgagtgggaggtg ccccgagagaagatcgccctcctccgagagctggggcagggctccttcggcatggtgtac gagggcaacgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacc gtcaacgagtcggccagcctgcgggagcggatcgagttcctcaacgaggcttccgttatg aagggtttcacctgccaccatgtggtccgcctcctgggggtggtgtccaagggccagccg acgctggtggtgatggagttgatggcccacggcgacctgaagagctacctccgctctctg aggccggaggccgagaataacccgggccgccctccccctaccctgcaagagatgattcag atggcggcggagatcgctgacgggatggcgtacctgaacgccaagaagttcgtgcaccgg gacctcgcagccagaaactgcatggtcgctcacgatttcactgtcaaaatcggagacttt ggaatgaccagagacatctacgaaacggattactaccggaaagggggcaagggcctgctc cccgtacggtggatggcaccggagtccctgaaggacggggtgtttaccgcttcttccgac atgtggtcctttggcgtggtcctttgggaaatcaccagcttggcggagcagccttaccaa ggcctgtctaacgaacaggtgttaaaattcgtcatggatgggggatatctggatcaacct gaaaactgtccagagagagtcaccgacctgatgcgcatgtgttggcagttcaaccccaag atgcgaccgaccttcttggagatcgtcaacctgctcaaggacgacctgcaccccagcttc ccagaggtgtccttcttccacagcgaggagaacaaggcccccgagagcgaggagctggag atggagttcgaggacatggagagtgtgcccctggaccggtcctgtcagagggaggaggcg gggagccgggagggagggtcctcgctgggcctcaagcggaactacgaggagcacaccccc tacacccacatgaacgggggcaagaagaacgggcggattctgaccctgcctcggtccaat ccctcctaa

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