Microcebus murinus (gray mouse lemur): 105872820 Help Entry 105872820         CDS       T07238                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur01521   EGFR tyrosine kinase inhibitor resistance mmur04151   PI3K-Akt signaling pathway mmur04217   Necroptosis mmur04380   Osteoclast differentiation mmur04550   Signaling pathways regulating pluripotency of stem cells mmur04620   Toll-like receptor signaling pathway mmur04621   NOD-like receptor signaling pathway mmur04630   JAK-STAT signaling pathway mmur04658   Th1 and Th2 cell differentiation mmur04659   Th17 cell differentiation mmur05140   Leishmaniasis mmur05145   Toxoplasmosis mmur05152   Tuberculosis mmur05160   Hepatitis C mmur05161   Hepatitis B mmur05162   Measles mmur05163   Human cytomegalovirus infection mmur05164   Influenza A mmur05165   Human papillomavirus infection mmur05166   Human T-cell leukemia virus 1 infection mmur05167   Kaposi sarcoma-associated herpesvirus infection mmur05168   Herpes simplex virus 1 infection mmur05169   Epstein-Barr virus infection mmur05171   Coronavirus disease - COVID-19 mmur05200   Pathways in cancer mmur05203   Viral carcinogenesis mmur05212   Pancreatic cancer mmur05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105872820 (JAK1)    04151 PI3K-Akt signaling pathway     105872820 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105872820 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105872820 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105872820 (JAK1)    04621 NOD-like receptor signaling pathway     105872820 (JAK1)    04658 Th1 and Th2 cell differentiation     105872820 (JAK1)    04659 Th17 cell differentiation     105872820 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     105872820 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105872820 (JAK1)    05203 Viral carcinogenesis     105872820 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105872820 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     105872820 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105872820 (JAK1)    05161 Hepatitis B     105872820 (JAK1)    05160 Hepatitis C     105872820 (JAK1)    05171 Coronavirus disease - COVID-19     105872820 (JAK1)    05164 Influenza A     105872820 (JAK1)    05162 Measles     105872820 (JAK1)    05168 Herpes simplex virus 1 infection     105872820 (JAK1)    05163 Human cytomegalovirus infection     105872820 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     105872820 (JAK1)    05169 Epstein-Barr virus infection     105872820 (JAK1)    05165 Human papillomavirus infection     105872820 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     105872820 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105872820 (JAK1)    05140 Leishmaniasis     105872820 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105872820 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmur01001]     105872820 (JAK1) Enzymes [BR:mmur01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105872820 (JAK1) Protein kinases [BR:mmur01001]  Non-receptor tyrosine kinases   JAK family [OT]    105872820 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  105872820 NCBI-ProteinID:  XP_012622585 Ensembl:  ENSMICG00000013750 UniProt:  A0A8B7GI89 LinkDB All DBs Position 2:complement(1067005..1184006) Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLSSGEYTAEEL CIRAAQECRISPLCHNLFALYDEKTKLWYAPNRTITADDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFNSNDSGNVVYYEVMVTGNLGIQWRQKPNVVPFEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVNINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGSQKQFKNFQIEVRKGRYSLHGSDRHFPSLEELMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGASEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDTECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPAAEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgcaaaaatgagg agctccaagaagaccgaggtgaatctggaggcccccgagccaggggtggaagtgatcttc tatctctcggaccgggagcccctccggctgagcagtggagagtacaccgcggaggagctg tgcatcagggctgcgcaggaatgccgtatctctcctctgtgccacaacctctttgccctg tatgacgagaagaccaagctgtggtatgctccgaatcgcaccatcactgctgatgacaag atgtcgctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gacaatgagcagtcggtgtggcgacattctccaaagaaacagaaaaatggctatgaaaag aaaaaggttccagatgcaacccctctgctggacgccagctcactggagtatctgttcgct cagggacagtatgatttagtgaaatgcctggctcccattcgagaccccaagacagagcag gatggccatgacattgagaacgagtgtctggggatggccgtcctggccatctcacactat gccatgatgaagaagatgcagctgccggaactgcccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctaaaagaattcaacaacaagaccatttgtgacagcagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaacgttgacaaaacat tatggtgctgaaatatttgagacctccatgttactgatttcatcagaaaatgagatgaat tggtttaattccaatgacagtggaaacgtcgtttactatgaagtgatggtgactggaaac cttggaatccagtggaggcagaaaccaaacgttgttccttttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaaacaaacacaaaaaggatgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcactcacatcgtcataaaggaatct gtggtcaacattaacaagcaggacaacaaaaaaatggaactgaagctgtcttcccacgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacggcagacgcccac cattacctctgcaccgacgtggcccccccgctgatcgtccacaacattcagaatggctgt cacggtccaatctgcacagaatatgccatcaataaattgcggcaagaaggaagcgaggag gggatgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgaccgtcacc tgcttcgagaagtctgaggtgctgggcagccagaagcagttcaagaacttccagatcgag gtgcgcaagggccgctacagcctgcacggctcagaccgccacttccccagcctggaggag ctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaacctactggtggctactaagaaggcc caggagtggcagcccgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatatcatgcagggcgagcaccttgggagaggcacgaggacgcacatctactctgggacc ctgatggattacaaggatgacgaaggagcttccgaggagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttccttggccttcttcgaggcagccagcatg atgaggcaggtctcccacaagcacatcgtgtacctctacggtgtctgcgtgcgtgacgtg gagaatatcatggtggaagagtttgtggaaggcgggcccctggatctcttcatgcaccgg aaaagtgatgttctcaccacaccttggaagttcaaagttgccaaacagctggccagtgcc ctgagctacctggaggataaagacctggtccatggaaacgtgtgcaccaaaaacctcctc ctggcccgagagggcatcgacaccgagtgcggccccttcatcaagctcagcgaccctggc atccccatcaccgtgctgtccaggcaagagtgcatagagcgaatcccatggatcgctccc gagtgtgtggaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acgctctgggaaatctgctacaacggcgagatccccctgaaagacaagacgctgatcgag aaagagagattctatgagagccggtgcaggcccgtgacaccatcttgcaaggagctggct gacctcatgacccgctgcatgaattacgaccccaatcagagacccttcttccgagccatc atgagagacattaataagcttgaagaacagaatccagacatagtttcagaaaaaaagcca gcagctgaagtggatcccacacattttgaaaagcgcttcctaaagaggatccgtgacttg ggagagggccacttcgggaaggttgagctctgcaggtatgaccctgagggtgacaataca ggggaacaggtggctgtcaaatctctgaagcctgagagcggaggtaaccacatagctgat ctgaagaaggaaatagagattttaaggaacctctatcatgagaacatcgtgaagtacaaa ggaatctgcacggaagacggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta aagtatgctgttcagatttgcaagggcatggactatctgggttctcggcaatacgttcac cgggacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggagac ttcggtttgactaaagcaattgaaactgataaggagtattacacagttaaggacgaccgg gacagccctgtgttttggtatgctccagaatgtctaattcagtgtaaattctacattgcc tctgacgtctggtctttcggagtgactctgcatgaactgctcacttactgtgactcagat tctagtcccatggctttgtttctgaaaatgataggcccgactcatggccagatgacagtc acaaggcttgtgaatacgttaaaagagggaaaacgtttgccatgtccacccaactgtcca gacgaggtttatcaacttatgagaaaatgctgggaattccaaccatccaatcggacgacc tttcagaaccttattgaaggatttgaagcacttttaaaataa

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