Mycobacteroides abscessus subsp. massiliense GO 06: MYCMA_2218
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Entry
MYCMA_2218 CDS
T02177
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mmv
Mycobacteroides abscessus subsp. massiliense GO 06
Pathway
mmv00860
Porphyrin metabolism
mmv01100
Metabolic pathways
mmv01110
Biosynthesis of secondary metabolites
mmv01120
Microbial metabolism in diverse environments
mmv01240
Biosynthesis of cofactors
Module
mmv_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmv_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MYCMA_2218
Enzymes [BR:
mmv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MYCMA_2218
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MYCMA_2218
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AFN64346
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Position
911261..912910
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AA seq
549 aa
AA seq
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MTRGRKKPGRILFVGSGPGDPGLLTVRARAVLTGATVAFTDPDVPQAVLDLVGSAVELPE
PAPAKPATGGDEAPAAANNEAAAEPPLTIDIRPALGDPADVAKTLVAEARSGVDVVRLVA
GDPLSIDSVLAEVHAVTRTQVAFEILPGLASSTAVPAYAGLPPGSAHTVADVRGDVDWAA
LAAAPGPLILHATPTHVPDAAKALIEHGLADQTLVAVTAQGTTCAQRTVETTLASLIDGV
PVDANDPHGPMTGALVLTIGRVVAGRSKLNWWESRALYGWTVLVPRTKDQAGEMSDKLVG
YGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFAEFGLDAR
AFSGVKIACVGQATADKVRAFGINPELVPAGEQSSLGLLDEFPPYDDVFDPVNRVLLPRA
DIATETLAEGLRERGWEIDDVTAYRTVRAAPPAAQTREMIKTGGFDAVCFTSSSTVRNLV
GIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLRTEGALP
PPRKKSRRR
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggggcgcaagaagccagggcgcattctgttcgttggttccggacctggagac
cccggtctgttgaccgtccgggcgcgcgcggtgctcacaggtgccacggtcgcgttcacc
gatcccgatgtgccgcaggcggtactcgatctcgtggggtcggcggtcgaacttcctgaa
cccgcgcccgccaaaccggcaacgggaggcgatgaggctcccgccgcggcgaataacgaa
gccgctgccgagccgccgctcaccatcgacattcgccccgccttgggtgatccggccgat
gtcgccaagacactcgtcgccgaggcccgcagcggtgtggacgtggtgcggttggtcgcc
ggcgacccactctcgatcgattcggtgctcgccgaggtccatgccgtcacgcggacccag
gtggcctttgaaatcctgcccggtctcgcttcgagcaccgcggtgcccgcctacgcgggc
ctgcccccgggctcggcccacaccgtggccgatgtgcgcggcgacgtggattgggcggcc
ctggccgctgctcccggcccgctgattctgcacgcgaccccgacgcatgtgcccgacgcc
gccaaggcgctcatcgagcatggcctggccgaccagactctggtcgcggtcaccgcgcag
ggcaccacgtgcgcacagcgcaccgtggagaccacactggcctcgctgatcgacggcgtc
ccggtggacgccaacgacccgcacgggccgatgaccggcgccctggtgctgacgatcggc
cgcgtggtcgccggccgctcgaagctgaactggtgggaaagccgtgccctgtacggctgg
accgtgttggtgccccgtaccaaggatcaagccggcgagatgagcgacaagctcgtcggg
tacggcgccttgcccgtcgaggtgccgaccattgccgtcgaacccccgcgcagtccggcc
caaatggaaagggctgtgaagggtttggtcgacggccggtaccagtgggtggtgttcacc
tccaccaacgcggtgcgtgccgtgtgggagaagttcgccgagttcggcctggacgcccgc
gccttctccggtgtgaagatcgcgtgtgtgggccaggcgaccgccgacaaggtgcgcgcc
ttcggcatcaacccggagctggttcctgccggtgagcagtcctcgctaggcctgctcgac
gagttcccgccctacgacgacgttttcgatccggtgaaccgggtgctgttgccgcgggcc
gacatcgccaccgagacccttgccgagggactgcgggaacgcggctgggagatcgacgac
gtgaccgcgtaccgcaccgtgcgcgcggccccgccggcggcgcagacccgcgagatgatc
aagaccggtgggttcgacgcggtctgcttcacatcgagctctacggttcgcaacctggtg
ggtatcgcgggcaagccgcatgcacgcaccattgtggcgtgcatcgggccgaaaaccgct
gagaccgcagtcgaattcgggttgcgagtggatgtgcagccggagacagcggccgtgggc
ccgctggtcgaggctctcgccgagcacgccgcccggctgcgcaccgaaggtgcactgccg
ccgccgcgcaagaagagccggcggagataa
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