Myotis myotis (greater mouse-eared bat): 118653930
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Entry
118653930 CDS
T07220
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00010
Glycolysis / Gluconeogenesis
mmyo00020
Citrate cycle (TCA cycle)
mmyo00620
Pyruvate metabolism
mmyo00785
Lipoic acid metabolism
mmyo01100
Metabolic pathways
mmyo01200
Carbon metabolism
mmyo01210
2-Oxocarboxylic acid metabolism
mmyo04066
HIF-1 signaling pathway
mmyo04922
Glucagon signaling pathway
mmyo05230
Central carbon metabolism in cancer
mmyo05415
Diabetic cardiomyopathy
Module
mmyo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118653930 (PDHA1)
00020 Citrate cycle (TCA cycle)
118653930 (PDHA1)
00620 Pyruvate metabolism
118653930 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
118653930 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118653930 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118653930 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118653930 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118653930 (PDHA1)
Enzymes [BR:
mmyo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
118653930 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
118653930
NCBI-ProteinID:
XP_036160820
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGMEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNEPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgctgtcgggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaag
tgtgaccttcaccggctggaagagggccctcctgtcaccacagtgctcaccagggaggat
gggctcagatactacaggatgatgcagactgtccgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcatggaagctggcataaatcccacagaccatctgatcacagcctatcgggct
catggctttacctttactcgtgggctttctgtacgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaaggaaaaggaggatcaatgcatatgtatgccaagaatttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagctgggattgctctggcc
tgcaagtataatggaaaagatgaggtctgtttgactttgtatggcgatggtgctgctaac
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatgggatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatgtccta
tgtgtccgggaggcaacaaagtttgcagctgcccattgtagggctggaaaggggcctata
ctaatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
tatcgtacacgagaggaaattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgctacagctgatcctgaaccacct
ttggaagaactaggctatcacatctactccaacgagccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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