Myotis myotis (greater mouse-eared bat): 118658025
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Entry
118658025 CDS
T07220
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo00310
Lysine degradation
mmyo01100
Metabolic pathways
mmyo05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
118658025 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
118658025 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmyo03036
]
118658025 (DOT1L)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118658025 (DOT1L)
Chromosome and associated proteins [BR:
mmyo03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118658025 (DOT1L)
HMT complexes
Dot1-containing complex
118658025 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
118658025
NCBI-ProteinID:
XP_036168762
LinkDB
All DBs
Position
Unknown
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTATPSPQDSYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKKLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDAVSLHLRGKGGLGRELEAEPSRLHLELDCSKFSLPHFSSMSPELSMNGHAAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASGKIPAGELHPRTEHAKENGLPYQSPGLANGIKLSPQDPRPSSPVALQM
TGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKRSTP
SPVPQTRESSSTLEKQMGANAHGAGSNAAGSKNLTLAPTGFYAGSVAISGALAGSPAPLA
PGVEPPVFDESSSSGSLFTTMGSRSSTPQHPQLLVQPRNSGPASPTHQLCVSPRLTAAQG
SLPDASKGDLPSEVGFSDPESEAKRRIIFTISAAASSTKQSPSNKHSPLPGGARGDSSQS
HGQDSRKRGRRKRASAGTPNLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQPL
EITAISSPESSLKSSPVPYPDNDQPPVLKKEKPLTQTNGAHYSPLTSDEEPGSEDEQGST
RIERKIATISLESKSPPKTLENGGSLVGRKPMPSSEPINSSKWKSTFSPIADLGLAKATD
SPLQASSALSQNSLFAFRPTLEELSSVDAKLATHPRKSFPGALSGPGGLSPISNPPNGFA
FSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKESSTEPGPFVNKRQLDGL
GGPKGEGVKGREGEVSLPVCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPPGGL
LSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVP
AAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHTVPSASTHPFGASFGSGAACR
STTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPLGRPPAGPPALHAPPPPPNAAL
PPAPALLPANSEPVLLQNLAPLPANQAFLPASSAASLPPANASLSIKLASLPHKVSRPSF
MVHHQPLPGLALAQASPMIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctat
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattacgtccta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgataagtacaaccgg
gccatcgacagcatccaccagctgtggaagggaaccacgcagcccatgaagctgaatacg
cggccatccaatgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgaca
gaccctgagaagctcaacaactacgagcccttctccccagaggtatatggggagacctcc
tttgacctggtcgcacagatgattgatgagatcaagatgaccgaggacgacctgtttgtg
gacctgggaagtggagtgggccaggtcgtgctgcaagtcgccgcggccaccaactgcaaa
catcactacggagtcgagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctaggcgccggcagcagcgagaaaacaagagtaatacaaccacccccacgaaggtgcct
gagagcaaggcggctgtgcctgcggacacctctgtggattctggtgctgaggaagagaaa
gcagcgaccaccgctatcaagaagccatctccctccaaagcacggaagaagaagctgaac
aagaagggccggaagctggctggacggaagcgcggacgtcccaagaagatgagcactgcg
aaccctgagcgtaagcccaagaagaaccctactgcactggacctcctgcacgcccagact
gtgtcccagacggcgacaccctcaccacaagattcatacaagtcacctcacagcccattt
tatcagctacctcccagcgtgcagcggcacccccctgaccaactgttgctagcacccacc
ccgcccgcactgcagaagctgctagagtccttcaagattcagtacctgcagttcctggca
tacacgaagacccctcagtacaaggccagcctgcagcagctattggaccaggagaaggag
aagaatgcccggttgctgggtgccgcacagcagctgttcggtcactgccaggcccagaaa
gaagaaataaagaagctttttcaacagaaactggatgagttgggagtgaaggcgctgacc
tacagtgacctgatccaagctcagaaagagatctcagctcacaaccagcagctgcgagag
cagacggagcagctggagaaggacaacagggagctgagaagccagagcctgcagctgctg
aaggctcggtgtgaggagctgaagttggactggtccacactgtccctggagaacctgcta
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcactgcctggagctg
cagattagcatcgtggagctggaaaagagccagcggcagcaggagctcctgcaactcaag
tcctgcgtgccgcctgatgatgctgtgtccctgcacctacgagggaaaggtggcctgggc
cgagaactggaggcggaacccagccggctgcaccttgaactggactgctccaaattctcc
ctgccccacttcagtagcatgagcccggagctctccatgaatggccacgcggccggctat
gagctctgcaacacactgagtcggccctcgtccaagcagaacaccccccagtacctggcc
tctccactggaccaggaggtggtgccatgtactcccagccacagcggccggccccggctt
gagaagctatctggcttggccttgccagactacaccaggctctccccggccaagctggtg
ctgagacgccacctgagccaggaccacactgccagtggcaagatacctgctggtgagcta
cacccacgaactgagcacgccaaggagaatggccttccataccagagcccgggcctcgcc
aatggcatcaagctgagccctcaggacccacggccctcatcccctgtggccttacagatg
acaggagaaaaaggcagtgagaagggtctgaaggagcgcgcctatgccagcagtggggag
gccatcaccagcctacccgtcagcattccactcagcactgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgttgcccaaccgtgccgagaagagaagcaccccc
agtcctgtgcctcagacccgagagtcctcgtccacacttgaaaagcagatgggtgctaac
gcccatggtgctgggagcaacgctgctgggagcaaaaacctcaccctggcgcccacaggc
ttctatgcaggctcagtcgccatcagtggcgccctggcaggcagcccggccccactcgct
cctggagttgagccccctgtcttcgatgagtcctccagctcggggagcctcttcactacc
atgggctcccgcagctccaccccacagcaccctcaactgctagtgcaaccccggaactcc
ggtccagcctcgcccacgcaccagctctgcgtcagcccccgactcaccgctgcccagggc
tcactccctgatgcgagcaaaggggaccttccctctgaggttggcttctcagatccagag
agcgaggccaagaggaggatcatcttcaccatctcagctgctgccagcagcaccaagcag
tcaccttccaacaagcacagccctctgcctgggggtgctcgtggagacagcagtcagagc
catgggcaggacagtcgaaagcggggcaggaggaagcgggcatccgcggggacccccaat
ctgagctcaggcgtgtcccccaagcgccgggccttaccatccgttgccggcctcttcact
cagtcttcagggtctcccctcaacctgaactctatggtcaacaacattaaccaacctttg
gaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtaccttacccg
gacaatgaccagccacccgtgctcaagaaagagaagcccctgacccagaccaatggagcc
cactactccccactgacctccgatgaggagccgggctctgaggatgagcaaggcagcacc
agaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccgaaaaccttg
gaaaatggtggcagcctggtaggaaggaagccgatgccctccagcgagcccatcaacagc
agcaagtggaagtccaccttctcacccatcgctgaccttggcctggccaaggctactgac
agcccgctacaggccagctccgctctgagccagaactccctgttcgcttttcggcccacc
ctagaggagctcagctcagttgatgccaagctggccacccaccccaggaagagctttccg
ggtgcactgtcggggcctggcgggctgagtcccatcagcaacccccccaacggctttgcc
ttcagcgggagcctggctgccgacctcagtttacacagtttcagtgatggtgcttctctc
tcccacaaggcccctgaggtggccagcctgggcgcccccctgagcttttccgccccgagg
ggtaaggagagcagcacggagcctggcccctttgtgaacaagaggcagctggatggactg
ggtggcccgaagggtgagggggtcaagggcagggagggagaagtcagcttgcccgtgtgc
acaccctcagacaaggcctcatcacatggcaaggtgggcaagggccgggaccgcgagcct
gatttcaaaaatggccacaatctcttcatttctgccgctgccgtgcctcctgggggcctc
ctcagcgggccaggcctcaccacagcagcgtcctcagcaagcggcacagccccctcctcc
cagacacaccggcccttcctgggcacttttgcacctggcccacagtttgccttgggcccc
atgtccctgcaggccaacttaggctcatctgtgctgcagtccttgttcagctctgtgccg
gctgctgctggcctagtgcacgtctcatccgctgcaaccagactgaccaactctcatgcc
atgggcagcttttcctccggtgtggcaggtggtgcagttggaggtatctttaaccacacg
gtgccttccgcctccactcatccgtttggagccagtttcggcagcggggctgcttgtcgc
agcaccacgctgagcttaaccccgatgcaggcggtggccagtacccccgcctcttccttt
caggccctgtcctctgtggagaccaggcagcccccaccccagcctcctctgcccctgggt
cggccccctgcggggccaccagcacttcacgcgcccccccctcctcctaacgctgccttg
cctcctgctcctgcactgctccctgctaactctgagcctgtgctcctgcagaatcttgcg
cccctcccggctaaccaagctttcttacctgcctcctctgccgcctctctgcctcctgct
aacgcctctctgtctatcaagctcgcttccctcccacacaaggtctcccgcccctccttc
atggtgcaccaccagcccctgcctggactggctctggcccaggcctcacccatgatccca
caggccagctccacggggccatccgccgtgtgggtttcccttggcatgccgcctccttat
gccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
