Mycolicibacterium neoaurum VKM Ac-1815D: D174_05490
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Entry
D174_05490 CDS
T02959
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mne
Mycolicibacterium neoaurum VKM Ac-1815D
Pathway
mne00860
Porphyrin metabolism
mne01100
Metabolic pathways
mne01110
Biosynthesis of secondary metabolites
mne01120
Microbial metabolism in diverse environments
mne01240
Biosynthesis of cofactors
Module
mne_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mne_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mne00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
D174_05490
Enzymes [BR:
mne01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
D174_05490
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
D174_05490
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
TruB_C
Motif
Other DBs
NCBI-ProteinID:
AHC24071
UniProt:
V5X8T3
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All DBs
Position
1142679..1144343
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AA seq
554 aa
AA seq
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MTGHAGNRGRKIRPGRITFVGSGPGDPGLLTTRARTVLANAATVFTDPDVPESVLALVGS
ELPPTSGPEPAATETPDGETVAAVVPGGPDVRPALGDPAEVAKTLAAEARNGLDVVRLVA
GDPLSVDAVIAEVNALARTQLNFEIVPGLPDTTAVPTYAGLPLGSSHTVADVRDPNVDWA
ALAAAPGPLILHATAGHLADAARTLVEYGLAENTPAVITAHGTTCQQHSVETTLVGLGDK
AILNAAEPSGGTPGPLSGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMS
DRLVTHGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEF
GLDARAFSGVKIACVGQATADRVRAFGINPELVPAGEQSSLGLLDEFPPYDEIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLRA
EGALPPPRKKSRRR
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgactgggcacgcaggtaaccggggccgcaagattcggcccggccgcatcacattcgtg
ggctccggcccaggtgatccgggcctgctgacaacgcgtgcgcggaccgtgctcgccaat
gcggcgacggtgttcaccgatcccgatgtgcccgagtcggtgctggcgctggtcggttcc
gaactgccgccgacctcgggccccgagcccgccgccaccgagacgcccgacggtgagacc
gtcgccgccgtggtgccgggtggtcccgatgtgcgaccagccctcggcgatcccgccgag
gtcgccaagacgctggccgccgaggcgcgtaacggtctcgacgtcgtccggctggtcgcc
ggtgacccgctgtcggtggacgcggtgatcgccgaggtcaatgcgctggcacggacccag
ctgaacttcgagatcgtgccgggcctgccggataccaccgcagtgccgacctatgccggt
ctgccgctgggctcgtcgcacacggtcgccgatgtgcgtgacccgaacgtcgactgggct
gcgctggccgccgcccccggaccgctgatcctgcacgcgaccgccggccacctggccgac
gccgcccgcacgctggtcgagtacggcctcgccgagaacacgccggccgtcatcaccgcg
cacggcaccacctgccagcagcattcggtggagaccacgctggtcggcctcggcgacaag
gccatcctgaacgcggccgagccctccggtggcacaccgggcccgctgtcgggtccgctg
gtcgtcacgatcggcaagacggtcgccaaccgcgcgaagctgaactggtgggagagccgg
gcgctctacggctggaccgtgctggtgccgcgcaccaaggatcaggccggcgagatgagt
gaccggctggtcacccacggcgcactgccggtcgaggtgcccaccatcgccgtcgagccg
ccgcgtagcccggcccagatggaaagggccgtcaagggtttggtggacggccggttccag
tgggtggtgttcacctccaccaacgccgtgcgtgccgtatgggagaagttcaacgagttc
ggcctggacgcccgcgcgttctcgggtgtgaagatcgcctgtgtcggccaggccaccgcc
gatcgggtgcgtgccttcggtatcaaccccgagctggtgcccgccggtgagcagtcctcg
ctgggcctgctcgacgagttcccgccgtatgacgagatcttcgacccggtgaaccgggtg
ctgctgccgcgcgccgacatcgccaccgagacgctggccgagggtctgcgtgaacgcggt
tgggagatcgaggatgtcacggcctatcgcaccgtccgtgcggccccgccgccggcgcac
acccgcgagatgatcaagaccggcgggttcgacgcggtctgcttcacctccagctcgacg
gtccgcaatctggtcggcatcgcgggtaaacctcacgcgcgcaccatcgttgcctgtatc
ggtcccaagaccgccgagacggcagtcgaattcggcctgcgcgtcgatgtgcagccggag
acggccgcggtcggtccgctggttgaggcgctcgccgagcatgccgcccggctgcgcgct
gagggtgcgctgcctccgccgcgcaagaagagccgccgccggtaa
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