Mustela nigripes (black-footed ferret): 132024042
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Entry
132024042 CDS
T09425
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp01100
Metabolic pathways
mnp04022
cGMP-PKG signaling pathway
mnp04740
Olfactory transduction
mnp04925
Aldosterone synthesis and secretion
mnp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132024042 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
132024042 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
132024042 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
132024042 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
132024042 (PDE2A)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
132024042 (PDE2A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
132024042
NCBI-ProteinID:
XP_059266090
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Position
1:complement(48563769..48655042)
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AA seq
945 aa
AA seq
DB search
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEQPPPPPPPQPCADSLQDALLSLGSV
IHIAGFRRAVKEALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKVREAVVSRKRL
GCSGLGPTDLPGKPLARLMAPLAPDTQVLVMPLVDKEAGAVAAVILVHCGQLSDSEEWSL
QAVEKHTLVALRRVQALQQRGLGAASEAVQNPPAAAAADQKGGVAYTDQDRKILQLCGEL
YDLDASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLQEETSFPLTTGRL
GQVVEDKKSIQRKDLASEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD
PFTDQDERVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQE
IITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQIL
NIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDL
ATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAI
DSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYH
NWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLA
ALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRI
FKDLQKMAEVGYDRNNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDL
EKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWT
KVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLDAE
NT seq
2838 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagcagccgccgccgccg
ccgccgccgcagccatgcgccgacagcctgcaggatgctttgctgagcctgggctccgtc
atccacatagcgggcttccggcgggctgtcaaggaggccctctcggctgtgctccccaaa
gtggagactgtctacacctacctgctggatggggagtcccggctggtgtgtgaagacccc
cctcatgagctgccccaggaggggaaagtccgagaggctgtggtctcccggaagcggctg
gggtgcagcggactgggccccacagacctgcccgggaagccgctggccaggctgatggct
ccactggctcctgacacccaagtgctggtcatgccgctcgtggacaaggaggctggggct
gtggcagcggtcatcttggtgcactgtggccagctgagcgacagtgaagagtggagcctg
caggcggtagagaagcataccctggtggccctgcgaagggtgcaggccttgcagcagcgc
gggctcggcgcggcctccgaagcggtccagaaccccccggcggcggcggcggcagaccag
aagggcggcgtcgcgtacacggaccaggaccggaagatcctacagctgtgcggggaactc
tacgacctggacgcctcttccctgcagctcaaagtcctccaatacctgcagcaggaaacc
caggcatctcgctgctgcctcctgctggtgtccgaggacaatctccagctttcctgtaag
gtcattggagataaagtgctacaggaggaaaccagctttccgctgacgacagggcgcctg
ggccaggtggtggaagataagaagtctatccagcggaaagatctcgcctctgaggatgtg
caacagctgcaaagcatgttgggctgtgagctgcaggccatgctctgcgtccctgtcatc
agccgggccactgaccaggtggtggccttggcctgcgccttcaacaagcttggaggagac
ccgttcacggaccaggatgagcgtgtgatccagcactgcttccactacacgagcactgtg
ctcaccagcaccctggccttccagaaggagcaaaagctcaagtgtgagtgccaggctctt
ctccaagtagcaaagaacctcttcactcacctggatgatgtctctgtcctgctccaggag
atcatcacagaggccagaaacctcagcaatgctgagatctgctccgtgttcctgctggac
cagaatgagctggtggccaaggtgttcgatgggggtgtggtggatgacgagagctatgag
atccgcatcccggctgaccagggcattgcgggccacgtggcaaccaccggccagatcctg
aacatcccagacgcttacgcgcacccgcttttctaccgcggcgtggacgacagcacgggc
ttccgcacgcgcaacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggt
gtggccgagctggtgaacaagattaacggaccatggttcagcaaattcgatgaggacttg
gcgacagccttctccatctactgtggcatcagcatagcccattccctcctatacaagaaa
gtgaatgaggcccagtatcgcagccacctagccaacgagatgatgatgtaccacatgaag
gtctctgatgatgaatacaccaaactcctccatgatggaatccagcctgtggctgccatt
gactccaactttgccagtttcacctacacccctcgctctctgcccgaggatgacacttcc
atggccattctgagcatgctgcaggacatgaatttcatcaacaactacaaaatcgactgc
ccgactctggcccggttctgtctgatggtgaagaagggctaccgggatcccccctaccac
aactggatgcacgccttttctgtctcccacttctgctacctgctctacaaaaatctggag
ctctccaactacctcgaggacatcgagatcttcgccttgtttatttcctgcatgtgtcat
gacctggaccacagaggcacaaacaactccttccaggtggcctcgaaatctgtgctggct
gcgctctacagctccgagggctctgtcatggagagacaccacttcgctcaggccatcgcc
atcctcaacacccacggttgcaacatcttcgaccacttctcccggaaggactatcaacgt
atgctggacctgatgcgggacatcatcttggccaccgacctggcccatcaccttcgcatc
ttcaaagacctccagaagatggctgaagtcggttatgaccggaacaacaagcagcaccac
agcctcctcctctgcctccttatgacctcctgtgacctctctgaccagaccaagggctgg
aagacgaccaggaagattgctgagctgatctacaaagagttcttctcccagggagacttg
gagaaggccatgggcaacaggccgatggagatgatggaccgggagaaggcctacatccct
gagctgcagatcagcttcatggagcacatcgcaatgcccatctacaagctgctgcaggac
ctgttccccaaggcggcagagctgtacgagcgcgtggcctctaaccgtgagcactggacc
aaagtgtctcacaagttcaccatccgcggcctcccgagcaacaactcgctggacttcctg
gacgaggagtatgaggtgcctgacctggatggcaccagggcccccgtcaacggctgctgc
agccttgatgctgaatga
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