Mycobacterium noviomagense: MNVI_04280
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Entry
MNVI_04280 CDS
T06809
Symbol
leuC1
Name
(GenBank) 3-isopropylmalate dehydratase large subunit 1
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mnv
Mycobacterium noviomagense
Pathway
mnv00290
Valine, leucine and isoleucine biosynthesis
mnv00660
C5-Branched dibasic acid metabolism
mnv01100
Metabolic pathways
mnv01110
Biosynthesis of secondary metabolites
mnv01210
2-Oxocarboxylic acid metabolism
mnv01230
Biosynthesis of amino acids
Module
mnv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mnv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MNVI_04280 (leuC1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MNVI_04280 (leuC1)
Enzymes [BR:
mnv01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MNVI_04280 (leuC1)
4.2.1.35 (R)-2-methylmalate dehydratase
MNVI_04280 (leuC1)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
GGGtGRT
Motif
Other DBs
NCBI-ProteinID:
BBY05110
UniProt:
A0A7I7P948
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All DBs
Position
508452..509855
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AA seq
467 aa
AA seq
DB search
MAPEPRTVFDKIWDAHVVSQLDADTALLYIDRIFLHEKSGAFALTSLRDDQRQVFDPHTV
FGTVDHSVDTRPGRTDASPLPDSQKFIEGFRAAAAEAGIPIFDLDDGRQGICHVTFPEQG
LVLPGMTMVCADSHTGTNGGLGALAWGVGVSTCETALASQTLAVKRPKTLQARFTGSLGD
GVYAKDLILALIATIGAAGATGYAIEYTGPTIESMPIEGRMTLCNMAVEAGGFTGIVSPD
AATLDYLKARPLALSGSDWQRAARQWLALRTDAGARFNGTVDIDVTTLTPQITWGTSPQH
CIGIDAPVPHPDTLPDPAGAAKALAYIGLTPGAPMTTIPIDAAFIGSCTNARLSDLQAAA
SLLAGRHVADGVTAICIPGSTAVKRAAEAQGIDRTFIDAGFQWRESGCGFCFFGGGEGFP
TGARVISSTNRNFEGRQGPGVRTHLASPATVAASALTGHITDPRTLP
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atggcaccggaaccgcgtacggtcttcgacaagatctgggatgcccacgtggtatcccag
ctcgatgccgacaccgcgctgctgtatatcgaccggatcttcctgcacgagaagagcggc
gcgttcgccttgaccagcctgcgcgacgatcagcgacaggtctttgacccgcacaccgta
ttcggcaccgtcgaccattcggtggacacccggcccggacgcaccgacgccagccccctg
cccgacagtcagaaattcattgaggggttccgagccgccgccgcagaggcaggaataccg
atcttcgatctcgatgacggtcgccagggaatttgtcacgttaccttccccgagcaggga
ctagtgctgcccggcatgacgatggtatgcgccgacagccacactggcaccaacggaggg
ctcggcgcactggcctggggcgtgggcgtgagcacttgcgagaccgccctggcctcccag
acgctggccgtcaaacggcccaagaccctgcaggcccgcttcaccggatcgctcggcgat
ggcgtctacgccaaagacctgattctggcgctcatcgcgaccatcggcgccgccggcgcc
accggctacgccatcgagtacaccgggccgaccatcgaatcgatgcccattgaaggccga
atgacgctgtgcaacatggccgtcgaagccgggggtttcaccggcatcgtctcccccgac
gccgccaccctggactacctcaaggcccgaccactagcacttagcggtagcgactggcag
cgcgccgcccggcaatggttggcactgcgcaccgacgccggggcacgcttcaacggcacc
gtcgacatcgacgtcaccaccttgacacctcagatcacctggggcaccagtccccagcac
tgcatcggcatcgatgcaccggtaccccatcccgacacactgcccgatcccgccggagcc
gcaaaagcactcgcctacatcggcctgaccccgggcgcgccgatgactacgataccgatc
gacgccgccttcatcggatcctgcaccaacgcacgactttccgatctgcaagccgcggca
tcactgctggccggacgccacgtcgccgacggggtcaccgccatctgcatccccgggtcg
accgcggtcaagcgcgctgccgaagcccagggcatcgaccgtaccttcatcgatgccggc
tttcagtggcgcgaatcaggctgcggtttctgcttcttcggcggcggcgaaggcttcccg
acgggcgcgcgtgtgatcagctccaccaaccgaaacttcgaaggccgccaaggccccggc
gtacgcacacatctggccagccccgccactgtcgccgcctccgcgctcaccggacacatc
accgatcccaggaccctgccatga
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