Mycobacterium noviomagense: MNVI_04650
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Entry
MNVI_04650 CDS
T06809
Symbol
kgd
Name
(GenBank) multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mnv
Mycobacterium noviomagense
Pathway
mnv00020
Citrate cycle (TCA cycle)
mnv00630
Glyoxylate and dicarboxylate metabolism
mnv00785
Lipoic acid metabolism
mnv01100
Metabolic pathways
mnv01110
Biosynthesis of secondary metabolites
mnv01120
Microbial metabolism in diverse environments
mnv01200
Carbon metabolism
mnv01210
2-Oxocarboxylic acid metabolism
Module
mnv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mnv_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mnv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MNVI_04650 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MNVI_04650 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MNVI_04650 (kgd)
Enzymes [BR:
mnv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MNVI_04650 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MNVI_04650 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MNVI_04650 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MNVI_04650 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
BBY05147
UniProt:
A0A7I7P998
LinkDB
All DBs
Position
550336..553995
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AA seq
1219 aa
AA seq
DB search
MYRKFRDDPSSVDPSWHEFLVDYNPEPTAESSTATDGAPAASAPAAPAPSTAPEPRPAPA
AKPAAAPAKPTDSNGAATPAAPAKPAAVAPAEGDEVQVLRGAAAAVVKNMSASLEVPTAT
SVRAVPAKLLIDNRIVINNQLNRTRGGKISFTHLLGYALVQAVKKYPNMNRHYAEADGKP
VAVTPAHINLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTAE
DFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASPQRIAELGIGKLI
TLTSTYDHRIIQGAESGDFLRTIHEMVLSDGFWDDVFRELGIPYEPVRWRADNPDSVVDK
NPRVIELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVLTHGLTLWDLDRVFKVDGFAG
AQYKKLRDVLSVLRDAYCRHVGVEYTHILEPEQQQWLQQRIETKHEKPTVAQQKYILSKL
NAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAVIDQCAEHALDEVVIGMPHRGRLNVL
ANIIGKPYRQIFTEFEGNLNPSQAHGSGDVKYHLGATGIYIQMFGDNDIQVSLTANPSHL
EAVDPVLEGQVRAKQDLLDKGDTEDGYSVVPLMLHGDAAFAGQGVVAETLNLALLPGYRV
GGTIHIIVNNQIGFTTSPEHSKSSEYCTDVAKMIGAPIFHVNGDDPEACAWVARLAVDFR
QKFKKDVVIDMLCYRRRGHNEGDDPSMTNPAMYDAIETKRGVRKSYTEALIGRGDISMKE
AEDALRDYQGQLERVFNEVRELEKHPVQPSESVESDQMIPAGLFTGIDKSLLARIGDAHL
ALPDGFNVHPRVKPVLEKRREMAYEGKIDWAFAELLALGSMVAEGKLVRLSGQDTRRGTF
SQRHSVVIDRDTGTEFTPLQLLTTNTDGSPTGGKFLVYDSPLSEFAAVGFEYGYTVGNPD
AFVMWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSGRIERF
LQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRNKAAVSEVKDFTEI
KFRSVLEEPTYEDGIGDRGKVRRVLLTSGKLYYELAARKAKDNRDDIAIVRIEQLAPLPR
RRLRETLDRYPSVEQYFWVQEEPANQGAWPRFGLELPELLPDKLTGLKRISRRAMSAPSS
GSSKVHAVEQQEIIDEAFS
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcaaattccgtgacgacccctcctcggtcgacccgagttggcacgagtttctg
gtcgactacaacccagagcccaccgctgagtcgtcgacggcgacggacggggcgccagct
gcgtcagcgccggccgccccagcgccgagcaccgcaccggagccacggccggcaccagct
gccaagccggcggcagccccggcgaagccaaccgatagcaacggcgcggccacaccggcg
gccccggcgaaaccggccgccgtcgcaccggccgaaggcgacgaagtgcaggtgctccgc
ggcgccgcggcggcagtggtgaaaaacatgtcggcgtcgctggaggtgccgactgccacc
agcgtccgcgctgttccggcgaagttgttgatcgacaaccgcatcgtgatcaacaaccag
ctcaatcgcactcgcggcggcaagatttcgttcacccatctgctgggctacgcgttggtg
caagcggtcaaaaagtaccccaacatgaatcggcactacgccgaggccgacggcaagccg
gtggccgtcacgcccgcgcacatcaacctgggtctggccatcgacttgcaaggcaaagac
ggcaagcgctcactggtggtggccggcatcaaacgctgcgagaccatgcgcttcgcgcag
ttcgtcaccgcttacgaggacatcgttcgccgcgcgcgcgacggcaagctcaccgccgaa
gactttgcgggcgtaacgatttcgctgaccaaccccggcaccatcggcaccgtgcactcc
gtgccgcggctgatggccggccaaggtgccatcatcggcgtcggcgcgatggaatatccg
gccgaattccagggcgccagcccccaacggatcgccgaactgggtatcggcaagctgatc
acgctcacctcgacgtacgaccaccgcatcatccagggcgcggaatccggcgactttcta
cgcaccattcacgaaatggtgctctccgacggcttctgggacgacgtcttccgtgagttg
ggcatcccgtacgagccggtgcgctggcgcgcagacaaccccgactcggtcgtcgacaag
aacccgcgggtcatcgagctgatcgccgcctaccgcaaccgcggccacctgatggccgac
atcgatccgctgcggttggacaacacccgcttccgcagtcaccccgacctcgatgtgctg
acgcacgggctgacgctgtgggatctcgatcgcgtattcaaggtcgacggtttcgcaggc
gcgcagtacaagaagctgcgcgacgtgctgtcggtgctgcgcgacgcctattgccgccac
gtcggcgtggagtacacccacatcctcgaaccagaacagcagcagtggctgcagcagcgc
attgagaccaagcacgagaagccgacggtcgcccagcagaaatacatcttgtccaaactc
aacgccgccgaggcgttcgagaccttcctgcagacgaaatatgttgggcaaaagcggttt
tcgctggagggcgcggaaagcgtgatcccgatgatggacgccgtcatcgaccagtgcgcc
gagcatgcgctcgacgaagtcgtcatcgggatgccgcaccgcggccggctcaacgtgctg
gccaacatcatcggcaagccgtaccggcagatctttaccgaattcgaaggcaacctgaac
ccgtcgcaggcccacggttccggcgacgtcaagtaccacttgggcgccaccggcatctac
attcagatgttcggagacaacgacattcaggtatcgctcaccgccaacccctcgcacctc
gaggccgtcgaccccgtgctggaagggcaggtgcgagccaagcaggacctgctggacaag
ggcgacaccgaagacggctactcggtggtgccgctgatgctgcacggcgacgctgccttc
gccgggcagggtgtggttgccgagacgctcaacttggcgctgctgcccggttaccgcgtc
ggcggcaccatccacatcatcgtcaacaaccagatcggcttcaccacttcgccggagcac
tccaagtccagcgaatactgcacggacgtcgcgaaaatgattggggcgccgatctttcac
gtcaacggcgacgacccggaggcgtgtgcgtgggtggcgcggctcgcggtggacttccgg
cagaagttcaagaaggacgtcgtcatcgacatgctgtgctaccgccgccgcggccacaac
gagggcgacgacccgtcgatgaccaacccggcgatgtacgacgccatcgagaccaaacgc
ggtgtgcgcaagagctacaccgaagcgctgatcggccgcggcgacatctcgatgaaggaa
gccgaggacgcgctgcgcgactaccagggccaactggagcgggtgttcaacgaagtccgc
gagctagaaaagcatcccgtgcaacccagcgagtcggtggagtccgaccagatgattccc
gccgggctgttcaccggcatcgacaagtcgctgctcgcccggatcggcgacgcgcacctc
gcgctgcccgacgggttcaacgtgcacccgcgggtcaaacccgtgttggagaagcgccga
gagatggcctacgagggcaagatcgactgggcgttcgccgagttgctggcgctgggatca
atggtggccgagggtaagctggtgcggctgtccgggcaagacacccgccgcggcacgttc
tcccaacgccattcggtggtcatcgaccgcgacaccggtaccgaattcactccgctgcaa
ctgctgaccaccaacaccgacggcagcccgaccggcggcaagttcctggtgtacgactcg
ccgctgtccgaattcgccgcggtcggtttcgaatacggctacacggtgggcaacccggac
gcatttgtcatgtgggaggcgcagttcggcgacttcgtcaacggcgcacagtcgatcatc
gacgagttcatcagctccggtgaggccaagtgggggcagttgtccaacgtggtgctgttg
ctgccgcacggccacgaaggacaaggccccgaccacacctcgggccgcatcgagcggttc
ctgcagctgtgggcggaggggtcgatgacgatcgcgatgccgtcgaccccgtcgaactac
ttccacctgctgcgccggcatgctctggacggcatccagcggccgctgatcgtgttcacg
ccgaagtcgatgctgcgcaacaaggccgcggtgagcgaggtcaaggacttcaccgagatc
aagttccgctcggtgctggaggaacccacctacgaggacggcatcggcgaccgaggcaag
gtccgtcgcgtcctgttgaccagcggcaagctgtactacgagttggccgcccgcaaggcc
aaggacaaccgcgacgacatcgcgatcgtgcggatcgagcagctggccccgctgccgagg
cggcggcttcgggaaacgctggaccgctacccatcggtggaacagtacttctgggtgcag
gaagagccggccaaccagggtgcatggccacgtttcggtctcgagctgccagagttgttg
ccggacaagctgaccgggctcaagcggatctcgcggcgggcgatgtcggcgccgtcgtcg
ggctcgtcgaaggtgcacgccgtcgaacaacaggagatcatcgacgaggcgttcagctag
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