Microtus oregoni (creeping vole): 121441180
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Entry
121441180 CDS
T08307
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00010
Glycolysis / Gluconeogenesis
morg00020
Citrate cycle (TCA cycle)
morg00620
Pyruvate metabolism
morg00785
Lipoic acid metabolism
morg01100
Metabolic pathways
morg01200
Carbon metabolism
morg01210
2-Oxocarboxylic acid metabolism
morg04066
HIF-1 signaling pathway
morg04922
Glucagon signaling pathway
morg05230
Central carbon metabolism in cancer
morg05415
Diabetic cardiomyopathy
Module
morg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
121441180
00020 Citrate cycle (TCA cycle)
121441180
00620 Pyruvate metabolism
121441180
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
121441180
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
121441180
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
121441180
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121441180
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
121441180
Enzymes [BR:
morg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
121441180
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
121441180
NCBI-ProteinID:
XP_041498253
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agcagagtgctagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcggcgaatggagctaaaggcagatcag
ctatataaacagaaaattatccgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgtgtgggcctagaggctggcataaaccccacggaccatctcatcacagcctatcgagct
catggcttcaccttcactcggggcctgcctgtccgagcaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggcggatcgatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctaggagcagggattgctctggcc
tgcaaatacaatggaaaagatgaggtctgtttgacattatatggcgatggcgctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaactaccttgtattttc
atctgtgagaataaccgctatggcatggggacatctgtcgagagagcagcggccagcaca
gattactacaaaagaggagattttattcctggactgagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcatattgtaggtctggtaaggggcccatc
ctgatggagctacagacttaccgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaagatgctgcccagtttgctacagctgatccagagccaccc
ttggaggaactaggctatcacatctacagtagtgatcctccctttgaagtgcgtggtgcc
aaccaatggatcaagtttaagtcagtcagttaa
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