Microtus oregoni (creeping vole): 121465153 Help Entry 121465153         CDS       T08307                                  Symbol Insr Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism morg  Microtus oregoni (creeping vole) Pathway morg04010   MAPK signaling pathway morg04014   Ras signaling pathway morg04015   Rap1 signaling pathway morg04022   cGMP-PKG signaling pathway morg04066   HIF-1 signaling pathway morg04068   FoxO signaling pathway morg04072   Phospholipase D signaling pathway morg04150   mTOR signaling pathway morg04151   PI3K-Akt signaling pathway morg04152   AMPK signaling pathway morg04211   Longevity regulating pathway morg04213   Longevity regulating pathway - multiple species morg04520   Adherens junction morg04910   Insulin signaling pathway morg04913   Ovarian steroidogenesis morg04923   Regulation of lipolysis in adipocytes morg04930   Type II diabetes mellitus morg04931   Insulin resistance morg04932   Non-alcoholic fatty liver disease morg04960   Aldosterone-regulated sodium reabsorption morg05010   Alzheimer disease morg05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:morg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     121465153 (Insr)    04014 Ras signaling pathway     121465153 (Insr)    04015 Rap1 signaling pathway     121465153 (Insr)    04066 HIF-1 signaling pathway     121465153 (Insr)    04068 FoxO signaling pathway     121465153 (Insr)    04072 Phospholipase D signaling pathway     121465153 (Insr)    04022 cGMP-PKG signaling pathway     121465153 (Insr)    04151 PI3K-Akt signaling pathway     121465153 (Insr)    04152 AMPK signaling pathway     121465153 (Insr)    04150 mTOR signaling pathway     121465153 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     121465153 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     121465153 (Insr)    04923 Regulation of lipolysis in adipocytes     121465153 (Insr)    04913 Ovarian steroidogenesis     121465153 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     121465153 (Insr)   09149 Aging    04211 Longevity regulating pathway     121465153 (Insr)    04213 Longevity regulating pathway - multiple species     121465153 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     121465153 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     121465153 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     121465153 (Insr)    04932 Non-alcoholic fatty liver disease     121465153 (Insr)    04931 Insulin resistance     121465153 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:morg01001]     121465153 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:morg04090]     121465153 (Insr) Enzymes [BR:morg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      121465153 (Insr) Protein kinases [BR:morg01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    121465153 (Insr) CD molecules [BR:morg04090]  Proteins   121465153 (Insr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  121465153 NCBI-ProteinID:  XP_041534280 LinkDB All DBs Position Unknown AA seq 1384 aa AA seqDB search MGSGKRRETTAVPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEISGTKGRQE RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQ ILKELEESSFRKTFEDYLHNVVFVPRKPSAGSGAEDTRPSRKRRSLEEVGNVTATMPTLP DFPNTSSTIAPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAA YVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKII IGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEV PREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVM KGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQ MTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLL PVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMEGGYLDPP DNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELE MEFEDMENVPLDRSSHCHREEPGGREGGSTLSIKRTYDEHIPYTHMNGGKKNGRVLTLPR SNPS NT seq 4155 nt NT seq  +upstreamnt  +downstreamnt atgggctccgggaaacgccgtgagacaacggccgtgccattgctggtggccgtagccgcg ttgctggtgggcgcagccggccacctgtaccctggcgaggtgtgccctggcatggacatc aggaacaacctgaccaggctgcatgagctggagaactgctcagtcatcgagggccatctg cagatcctcttgatgttcaaaactagacccgaagatttccgagacctcagtttccccaaa ctcatcatgattacagactacctgcttcttttccgtgtctatggcctggagagtttgaaa gacctcttccccaaccttacagtcatccgaggctcccgcctcttcttcaactatgccctg gtcatctttgagatggtccacttgaaggagctggggctctacaacctcatgaacatcacc cggggctctgtccgcattgagaagaataatgagctctgttacctggccaccattgactgg tctcggatcttggattctgtggaggacaactacatcgtgctgaataaagatgacaatgag gagtgtggggatgtctgtccaggcactgccaagggcaagaccaactgccctgccaccgtc atcaatgggcagtttgtggaacggtgctggacacacagtcattgtcagaaagtttgtccg accatctgtaagtcacatggctgcacagctgaaggcctgtgctgccacaaggagtgccta ggcaactgttcggaacccgatgaccccaccaagtgtgtggcctgtcgcaacttctacctg gacggtcgctgtgtggagacctgcccgcccccttactaccacttccaggattggcgctgt gtgaacttcagcttctgccaagaccttcactacaaatgcagaaactctaggaagcctggc tgtcaccaatacgtcattcacaacaacaagtgcatcccggagtgtccttctggctataca atgaattccagcaacttgatgtgcaccccatgtctgggaccctgccctaaggtctgccaa atcctcgatggcgagaagaccattgactctgtgacatctgcccaggagctccgaggctgc actgtgatcaatggcagcctgatcatcaacattcgaggaggcaacaatctggcagctgag ctggaggctaaccttggcctcattgaagaaatctcagggttcctaaagatccggcgctcc tatgctctagtatcgctttctttcttccggaagctacatctgattcgaggagagaccttg gaaatcgggaactactctttctatgccttggacaaccagaacctcaggcagctctgggat tggagcaagcacaacctcaccatcactcagggcaagctcttcttccactacaaccccaaa ctctgcttgtcagaaatccataagatggaagagatttctggaactaagggccgccaggag aggaacgatattgccctgaagaccaatggggaccaggcatcctgtgaaaatgagttactt aaattttctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactgg ccccccgacttccgagacctcttgggattcatgcttttctacaaagaggccccttatcag aatgtgacggagtttgatggtcaggatgcttgtggctccaacagctggactgtggtagat attgacccaccccagaggtccaacgaccccaagtctcaaaccccaagccaccctgggtgg ctaatgcggggtctcaagccctggacccaatatgccatctttgtcaagaccttggttacc ttctcagatgaacgccggacctacggagccaaaagtgacatcatctatgtgcagacagat gccaccaatccttctgtccccctggaccccatatcggtttctaattcctcatctcagatt atcttaaaatggaagcccccctctgacccgaacggcaacatcacacactacttggtctac tgggagaggcaggcagaggacagtgagctattcgagttggattattgtctcaaagggctg aagctcccctcacggacctggtccccaccttttgagtctgatgattctcagaagcacaat cagagtgagtatgacgattcggccagcgaatgctgctcctgccccaagaccgactctcag atcctgaaggagctggaggagtcttcgttcaggaagacctttgaggattacctgcataat gtggtttttgtccccagaaaaccctctgcaggcagtggtgccgaggacactaggccatct cgaaagcgaagatcccttgaagaggtggggaatgtgacagccaccatgcctacacttcca gattttcctaacacctcctccaccattgcacctacgagtcaggaggaacacaggccattt gagaaagtggtgaacaaggagtcacttgtcatctctggcctgagacacttcactggctat cgcattgagctgcaggcatgcaaccaagactccccagaagagaggtgcagtgtggctgcc tacgtcagtgcccgaaccatgcctgaagctaaggcagatgacattgttggccctgtgacc cacgaaatctttgagaacaatgttgtacacttaatgtggcaagagccaaaggagcccaat ggtctgattgtgctgtatgaagtgagctatcggcgatatggtgacgaggagctgcacctc tgtgtctccaggaagcattttgccctggagcggggctgcaggctgagagggctctcccca gggaactacagtgttcgagtccgggctacctccttggcaggcaatggctcctggacagaa cccacctatttttacgtgactgattatttagatgtcccatcaaatattgccaaaattatc attgggcccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctattc ctgagaaagaggcagccagatgggccgatgggaccactgtatgcatcttcaaaccctgaa tacctcagtgccagtgatgtgtttccttcttctgtgtacgtgccggatgagtgggaggtg cctcgagagaagatcacccttctacgagagctggggcagggatcctttggtatggtgtat gagggcaatgccaaggatatcatcaagggtgaggcagagacccgtgttgcagtgaagact gtcaatgagtcagccagtctccgagaacggatcgagttcctcaacgaggcatcggtcatg aagggattcacctgccatcatgtggttcgcctccttggggtggtgtccaaaggccagcca acactggtagtgatggagttgatggctcatggagacctgaagagtcacctccgttccctg cgcccggatgctgaaaataacccaggccgtcctccccctaccttgcaagagatgattcag atgacagcagaaattgctgatggcatggcatacttgaatgccaagaagtttgtacaccgg gacctggcagctcgaaactgcatggttgctcatgattttaccgtcaaaattggagacttt ggaatgacgagagacatctatgagacagattactatcggaaagggggcaagggcttgctg cctgtacggtggatgtcacctgagtccttgaaggatggagtctttactgcttcttctgat atgtggtcctttggggtggtcctttgggaaatcactagcctggctgagcaaccataccaa ggcctgtctaacgaacaggtgttgaaatttgtcatggaaggaggctatctggatccacct gataattgtcccgagagactcactgacctgatgcgcatgtgctggcagttcaaccccaag atgaggccaaccttcctggaaattgtcaacctgctgaaggatgacctccaccccagcttt ccagaggtttccttcttctacagcgaagagaacaaggctcctgagagtgaggagctggag atggagttcgaggacatggagaatgtccccttggatcggtcctctcactgtcacagggaa gaacctgggggccgggagggagggtccactctgagcatcaaacggacctatgatgaacac atcccatacacccacatgaacgggggcaagaagaatgggcgtgtgctcaccctgcccagg tcaaacccttcctaa

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