Mycobacterium ostraviense: LTS72_21770
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Entry
LTS72_21770 CDS
T07946
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mot
Mycobacterium ostraviense
Pathway
mot00860
Porphyrin metabolism
mot01100
Metabolic pathways
mot01110
Biosynthesis of secondary metabolites
mot01120
Microbial metabolism in diverse environments
mot01240
Biosynthesis of cofactors
Module
mot_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mot_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mot00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LTS72_21770
Enzymes [BR:
mot01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LTS72_21770
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LTS72_21770
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UGT94507
LinkDB
All DBs
Position
complement(4770814..4772484)
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AA seq
556 aa
AA seq
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MTRGRKPAPGRITFVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPEPVLALIGKDLPPV
SGPAPATAHAGENVSVAAGEPAPGAPAVVSSGPDIRPALGEPVDVAKTLTAEARSGADVV
RLVAGDPLSVDAVITEVNAVARTHLHFEVVPGLAATSAVPTYAGLPLGSSHTVADVRGEL
DDTDWDALAAAPGPLILQATASHLADAARTLLDHELADTTPCVVTAHGTTCQQRSVETTL
QGLTDPAILGGADPAGPFAGPLVVTIGKTVSNRGKLNWWESRALYGWTVLVPRTKDQAGE
MSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFG
EFGLDARAFSGVKIACVGESTADRVRAFGISPELVPSGEQSSMGLLDEFPPYDSIFDPVN
RVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTSS
STVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARL
RAEGALPPPRKKSRRR
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgagggcgtaagccggctccgggccgcatcactttcgtgggttccggtcccggc
gacccgggtctgctgaccacccgggctgccgcggtgttggccaacgccgctctggtgttc
accgacccggacgtacccgagccggtgctggcgctgatcggcaaggatctgccaccggta
tccgggccggcgccggcaaccgcacatgcgggggagaacgtcagcgtggctgcgggagag
cccgccccgggcgccccggcggtggtctcgagcggccccgacatccggccggcgctgggc
gaacccgtcgacgtggccaagacgctgaccgccgaggcccgttcgggtgccgatgtggtg
cggctggtggccggcgacccgttgtcggtggacgcggtgatcaccgaggtgaacgccgtg
gcacgcacccacctgcacttcgaggtcgtgcccgggctggccgccaccagcgcggtcccg
acctatgccgggctgccgctgggctcctcgcacacggtggccgacgtgcgcggcgaactc
gatgacaccgactgggacgcgctggccgccgcccccggaccgctgatcctgcaggcgacc
gcgtcgcatctggccgacgctgcacgcaccctgctcgaccacgagctggccgacacgacg
ccgtgcgtggtcaccgcgcacggcactacctgccagcagcgatcggtcgaaaccacgctg
cagggactgaccgatccggccatcctgggcggcgccgaccccgctggcccgttcgccggg
ccgctggtggtgaccatcggcaagaccgtgagcaaccggggcaagctgaactggtgggag
agccgggcgctgtacggctggaccgtgctggtgccgcgcaccaaggaccaggccggcgag
atgagcgagcggttgacgtcctacggagcgctgccggtcgaggtgccgaccattgccgtc
gaaccgccgcgcagccccgcgcaaatggaacgcgccgtcaagggcctggtcgatggccgg
ttccaatgggtggtgttcacctcgaccaacgcggtgcgggccgtctgggagaagttcggc
gaattcggtctggatgcgcgggcgttctccggggtcaagatcgcttgtgtcggcgagtcg
accgccgaccgggttcgtgccttcgggatcagccccgagctggtgccgtccggcgagcag
tcgtcgatgggtctgctcgacgaattcccgccgtatgacagcattttcgacccggtcaac
cgggtcctgctgccgcgcgccgacatcgccaccgaaacgctggccgaggggctgcgcgaa
cgtggctgggaaatcgaggacgtcaccgcctaccggaccgtgcgggccgcgccgccgccg
gcggccacccgcgaaatgatcaagacgggcggtttcgacgcggtgtgcttcacctcgagc
tcgacggtgcgcaacctggtcggcattgccggcaagccgcacgcgcgcaccatcatcgcc
tgtatcggccccaagaccgccgagaccgccgccgaattcgggcttcgggtggatgtccag
ccggagaccgccgcggtgggtccgctggtcgacgccctggccgaacatgccgcccgattg
cgcgccgagggcgcgctgccgccgccgcgcaagaagagccgcaggcgctag
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