Mycobacterium paraterrae: MKK62_16445
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Entry
MKK62_16445 CDS
T08203
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mpaa
Mycobacterium paraterrae
Pathway
mpaa00290
Valine, leucine and isoleucine biosynthesis
mpaa00660
C5-Branched dibasic acid metabolism
mpaa01100
Metabolic pathways
mpaa01110
Biosynthesis of secondary metabolites
mpaa01210
2-Oxocarboxylic acid metabolism
mpaa01230
Biosynthesis of amino acids
Module
mpaa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mpaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MKK62_16445 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MKK62_16445 (leuC)
Enzymes [BR:
mpaa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MKK62_16445 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MKK62_16445 (leuC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
UMB68051
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All DBs
Position
3761836..3763272
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AA seq
478 aa
AA seq
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MTKTSAPGSAGRPRTLAEKVWDDHVVASGGGTEPDLIYIDLHLVHEVTSPQAFDGLRLEG
RPVHRPDLTLATEDHNVPTIDIDKPIADPVSRNQVETLRRNCAEFGIRLYPMGNIEQGIV
HVVGPQLGLTQPGMTVVCGDSHTSTHGAFGAIAMGIGTSEVEHVLATQTLPLRPFKTMAV
NVDGQLPAGVTAKDIILAVIAKIGTGGGQGHVIEYRGSAIESLSMEARMTICNMSIEAGA
RAGMVAPDATTYEFLRGRPHAPTGAQWDAAQAYWDQLRTDEGAEFDTEVYLDAASLTPFV
TWGTNPGQGVPLGASVPDPELMTDDHERQAAEKALAYMDLRPGMPMREIAVDTVFVGSCT
NGRIEDLRAVADILRDRKVADGLRMLIVPGSMRVRAEAESEGLDQIFTAAGAEWRQAGCS
MCLGMNPDQLAPGERCAATSNRNFEGRQGKGSRTHLVSPAVAAATAVRGTLSAPADLN
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
gtgacgaaaacttcggccccggggtctgccgggcggccgcgcacgctggcggagaaggtt
tgggatgaccatgtggtggcatcgggaggtggcaccgagcccgacctgatctacatcgat
ctgcatctggtgcacgaggtgaccagtccgcaagccttcgacggactgcgcctcgagggt
cgaccggtccaccgcccagacctgacattggccaccgaggatcacaatgtgccgacgatc
gacatcgacaagccgatcgccgatcccgtctcccgcaatcaggtggagacgcttcgccgg
aactgtgcggaattcgggattcggctctacccgatgggaaatatcgagcagggcatcgtc
cacgtcgtcggcccgcaactggggctgacccagccgggcatgaccgtcgtgtgcggcgac
agtcacacctcgacgcacggcgcgttcggcgcaattgcaatgggcatcggcacatccgag
gtcgagcacgtgctggcgacgcagacgcttccgctgcggccgttcaagacgatggccgtc
aacgttgacggacaactgccggccggcgtgaccgccaaggacatcattctggcggtgatc
gccaagatcggcactggtggcggacaaggccacgtcatcgaataccgcggcagcgccatc
gaatccctgtccatggaagcccggatgacgatctgcaacatgagcatcgaagccggggcc
agggcgggaatggtggcaccggatgccactacctacgaattcctgcgcggtcgcccgcac
gctccgaccggtgcgcagtgggatgcggcgcaggcatattgggatcagctgcgcaccgac
gagggcgccgaattcgacaccgaggtctacctggatgccgcgtcgttgacgccgtttgtg
acgtggggcaccaatccaggtcagggtgttccgctgggagccagcgtgccggaccccgag
ctgatgaccgatgaccacgagcgtcaggcggccgagaaagcgctggcgtacatggacctt
cggcctgggatgccgatgcgtgagatcgcggtcgacaccgtgttcgtcggatcgtgcacc
aacggccggatcgaggatctacgcgcggtcgccgacatcttgcgggaccggaaagtggcc
gacggccttcgcatgctgatcgtgcccggctcgatgcgggtgcgcgcagaggccgaaagt
gaaggcctggaccagatcttcaccgccgcgggtgccgagtggcgccaggccggctgctcg
atgtgtctgggtatgaaccctgaccagctggcccctggcgagcgctgcgccgccacatcg
aaccggaatttcgaaggccgccagggcaagggcagccgtacgcatctggtgtcaccggcg
gttgccgctgccaccgcggtccgcggaacgctttccgcgccggccgacctgaattga
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