Mus pahari (shrew mouse): 110314162
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Entry
110314162 CDS
T05929
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah00010
Glycolysis / Gluconeogenesis
mpah00020
Citrate cycle (TCA cycle)
mpah00620
Pyruvate metabolism
mpah00785
Lipoic acid metabolism
mpah01100
Metabolic pathways
mpah01200
Carbon metabolism
mpah01210
2-Oxocarboxylic acid metabolism
mpah04066
HIF-1 signaling pathway
mpah04922
Glucagon signaling pathway
mpah05230
Central carbon metabolism in cancer
mpah05415
Diabetic cardiomyopathy
Module
mpah_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110314162 (Pdha1)
00020 Citrate cycle (TCA cycle)
110314162 (Pdha1)
00620 Pyruvate metabolism
110314162 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110314162 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110314162 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110314162 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110314162 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110314162 (Pdha1)
Enzymes [BR:
mpah01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110314162 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
110314162
NCBI-ProteinID:
XP_021044286
Ensembl:
MGP_PahariEiJ_G0032075
LinkDB
All DBs
Position
X:complement(138362023..138378635)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSEPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agccgagtgctggttgcttcccgtaactttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcgccggatggagctaaaggcggatcag
ctgtataagcagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgcgtgggcctggaggctggcataaaccccacggaccatctcatcaccgcctatcgagcg
catggcttcaccttcactcgaggcctacccgtccgagcaatccttgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggcgggtcaatgcacatgtacgccaagaacttc
tatggaggcaatggcattgttggagctcaggtgcccctgggagcaggaattgctctggcc
tgcaagtacaatggaaaagatgaggtctgtttgacattatacggcgatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagcactgtggaaattaccttgcattttc
atctgtgaaaacaaccgctatggaatggggacatctgtcgagagagcagcagccagtacg
gactactacaaaagaggagattttattcctggactcagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcctattgcaggtctggtaaggggcccatc
ctgatggagctacagacttaccgctaccatggacatagcatgagtgaccctggagtaagc
taccgcactcgagaggagatccaggaagtaagaagtaagagcgaccctatcatgcttctc
aaggacagaatggtgaacagcaatcttgccagtgtcgaagaattaaaggagattgatgta
gaagtgaggaaagaaatcgaggatgctgcccagtttgccacggctgatcctgagccacca
ctggaggaactaggctatcacatctacagcagtgagcctcccttcgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
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