Mus pahari (shrew mouse): 110326191
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Entry
110326191 CDS
T05929
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah00310
Lysine degradation
mpah01100
Metabolic pathways
mpah05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
110326191 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
110326191 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mpah03036
]
110326191 (Dot1l)
Enzymes [BR:
mpah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
110326191 (Dot1l)
Chromosome and associated proteins [BR:
mpah03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
110326191 (Dot1l)
HMT complexes
Dot1-containing complex
110326191 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
110326191
NCBI-ProteinID:
XP_021060037
Ensembl:
MGP_PahariEiJ_G0031013
LinkDB
All DBs
Position
9:45290369..45330162
Genome browser
AA seq
1736 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRETKSNATTPTKVP
ESKAAATEAPADSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAS
AERKSKKSQSALDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSC
VPPDDALSLHLRGKGALGRELEADTGRLRLELDCAKISLPHLSSMSPELSMNGHAASYEL
CNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHTGASKAATSEPHPRPEHAKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSATLEKQTGASAHGAGGAGAGSRSLAVAPTGFYAGSVAISGALASSPAPLAS
GMESAVFDDSSGPSSLFATMGSRSTPPQHPPLLSQSRNSGPASPAHQLTASPRLSVTTQG
SLPDTSKGELPSDPAFSDPESEAKRRIVFSISVGASSKQSPSTRHSPLTSGTRGDCVQSH
GQDSRKRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESKSPPKTLENGGGLVGRKSVPSSEPINSSKWKSTFSPISDLGLAKAVDS
PLQAGSALSHSPLFSFRPSLEEPAAEAKLPTHPRKSFAGSLGAAEGPSPGTNPPNGLAFS
GGLAADLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGG
LKGEGNANKESGESLPLCGPSDKASLPHGSRANKGRDRELDFKGGHNLFISAAAVPPGGL
LGGPGLVTVASSAGSATPTAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLF
STVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSG
AVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPP
PPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPHSSAASLQPANASLSVKLASLPHK
VSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5211 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcctgtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccatgatgctgctcatgagattattgagact
atccggtgggtctgcgaggaaatcccagatctcaagctggccatggagaactatgtcctg
attgactacgacaccaaaagttttgaaagcatgcagaggctgtgtgacaaatacaaccgg
gccatcgatagcatccaccagctgtggaagggcactacacagcccatgaagctgaatact
cggccgtccaatggactcctgcggcacatcctgcagcaggtttataaccactctgtcact
gacccggagaagcttaacaactacgagcctttctcccccgaggtttatggggagacctcc
tttgacctggtggcccagatgattgatgagatcaagatgacagaggatgacctgtttgtc
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgcggccaccaactgcaaa
catcactacggagtggagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggaatggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggcggcagaatcgtatcctcaaagccctttgcccctctgaacttcaggatcaac
agcaggaacttgagtgacattggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctctgtgtcgtggactggcaagcctgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggca
gcgaggcgcaggcagcagcgagagaccaagagcaatgcgaccacgcccaccaaagtccct
gagagcaaagcagctgccaccgaggcccccgcggattctggtgctgaggaagaaaaatca
ggtgtggctactgtcaaaaagccatctccctccaaagcccggaagaagaaactgaataag
aaagggagaaagatggctggccggaaacgtggacggcccaagaagatgagtgctgccagt
gccgagcgcaagtctaagaagagccaaagcgcactggatctcctgcactctccgccccca
gccccaccctcggcctcaccccaggatgcgtacagggcacctcacagcccattctaccag
ctacctccgagcacacagctgcactcacccaacccactgctagtggcgcctaccccgcct
gcgctgcagaagcttttagagtccttcaaaatccagtacctgcagttcctggcttatacg
aagaccccacagtacaaggccaacctacagcagcttctggaccaggagaaggagaagaac
acacagctcctgggcacagcccagcagctctttggccattgccaggcccaaaaggaagag
atccgcaggctgtttcagcagaagctggatgagttgggcgtgaaggcactgacctacaat
gacctgattcaggcccagaaggaaatctctgcccacaaccagcagctgcgggagcagtcg
gaacagctggagaaggacaacagcgagcttcggagccagagcctgcggctgctcagggcc
cggtgcgaggagctgaggcttgactggtccacactgtccctggagaacctgcggaaagag
aagcaggccctgcggagccagatctcagagaagcagcggcactgcctggagctgcagatc
agtatcgtggagctggagaagacccagcgccagcaggagctcctgcagttgaagtcctgt
gttccaccagatgatgctctgtctctgcatctgcgcggcaagggcgccctgggccgagag
ctagaggctgacactggacgcttacgtcttgagctggactgtgccaagatctccctgcca
cacctcagcagcatgagccctgagctgtccatgaatggccatgctgccagctatgagctc
tgcaatgcagctagtcggccatcatccaagcagaacaccccccagtacctggcttctccc
ttagaccaggaggtcgtaccttgcacccctagccacagcggccggcctcggctagagaag
ctgtctggcctggctttgcctgattatacccggttgtcacctgccaagattgtgttgagg
cggcacctgagccaggaccacactggggctagcaaagccgctaccagtgagccacaccct
cggccagagcacgccaaggagagcagccttccctaccagagccctggcttgtccaacagc
atgaagctcagcccccaggatccaccgctggcctccccggcgacctcgcccctcacctcc
gagaagggtagtgagaagggtgtgaaggagcgtgcctacagcagccatggggagaccatc
accagcctacctgttagcattccactcagcacagtgcagcccaacaagctacccgtcagc
atcccactggccagcgtggtactgcccagccgtgccgagagggcgaggagcactcccagc
cctgtgcctcagccccgggactcttcagccacacttgagaagcagactggtgcttccgcc
catggtgcagggggtgctggagcagggagcaggagcctcgctgtggcgcccacaggtttc
tatgctggttcggtggccatcagtggggccctggccagcagcccagcacctctggcctct
ggaatggaatctgctgtttttgatgactcctctggtcccagcagcctctttgccaccatg
gggtctcgcagcacaccaccacaacacccacctctcctgtcgcagtcccgcaactcgggt
cctgcctctcctgcccaccaactcacagccagtccccgcctgagtgtgaccactcagggc
tcgctgccagacaccagcaaaggggaactgccttctgatcctgccttctcagacccagag
agcgaagcaaagaggaggattgtgttcagcatttcagttggtgccagctccaagcagtca
ccttccaccaggcacagccccttgacctctggcacccgaggggactgtgtgcagagccac
ggacaggacagtcgtaagcgcagcagaaggaagcgtgcatcagctggaacacctagcctc
agcacgggtgtgtcccccaagcgccgggctctgccaactgttgctggcctctttacacag
tcctcggggtctcctcttaatctcaactccatggtcagcaacatcaaccagccgctggag
atcacagccatctcatcccctgagagctccctgaagagctcccccaccccctaccaggac
catgaccagcctccggtgctcaggaaggagcggcccctaggaccaactaatggggcccac
tactcgccactgacctcagatgaggagccaggctctgaggacgagcccagcagtgcccga
attgagagaaaaattgcaacaatctctttagaaagcaaatctcccccgaagacactggaa
aatggtggtggcttggtgggaaggaagtcggtcccttcgagcgagcctatcaacagcagc
aaatggaagtccaccttctctcccatctctgacctcggcttggctaaggccgtggacagt
ccgctacaggctggctctgccctgagccacagccccctgttctctttccggccatccctg
gaggagcctgctgctgaggccaagctccccacccacccaaggaaaagctttgcaggctct
ctgggtgcagccgaggggccaagccctggcaccaaccctcccaatggcctggccttcagc
gggggccttgctgcagacctcggtttacacagcttcaatgacggtgcttccctctcccac
aagggccctgatgtgactggcctgagtgcctctctgagcttcccgtcccagaggggcaag
gacagtaccacagaggccaaccctttcctcagcaggcggcaacccgagggcctgggtggc
ttgaagggtgagggcaacgcaaacaaggagtcaggagagagcctgcccctgtgcgggccc
tcggacaaggcctcactgccgcatggcagcagggccaacaaaggccgtgaccgcgagctg
gacttcaagggcggccacaacctcttcatctctgctgcagccgtgcctccaggtggcctc
cttggtggccctggtcttgtaactgtggcttcttctgcaggcagtgcgacacccactgcc
caggctccccggcctttcctgagcacctttgcccccgggccccagtttactctgggcccc
atgtccctgcaggccaacctggggtctgtggccggctcctctgtgctgcagtccttgttc
agcactgtgccagctgctgcaggcctggtgcatgtgtcatccactgcgacccgactgacc
aactcacacaccatgggcagcttctcttctggggtggccggcggaaccgttggaggtgtc
tttacccacgcggtgccctccgcctctgctcacccgtttggagctggtgtcggcagcggg
gctgtgtgtagcagtgccacgctgggcctgagcccgctgcaggcggcggccagcacctcg
gcttcttcctttcaggccgcggcttcggtcgagactcggccgccccctccacctccccta
cttcctcctcagcatctaggccggccccctgcggggccacctgtcctccatgcaccccct
cctcctaacgtcgccttgcctcctccgcctgcgctgctggcttctaaccctgagccagtg
cttctgcagagcctggcctccctcccagctaacaacgctttcttaccccactcctctgcc
gcctctctgcagcctgctaatgcctctctatctgtcaagctcgcctccctcccacacaag
gtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggccctggcgcag
gccgcgcccgccgccccacaggccagcacctcggggccatctgctgtgtgggtttccctt
ggcatgccgcctccttatgccgcgcacctttcgggggttaagcctcgataa
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