Mycolicibacterium phlei: MPHLCCUG_02059
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Entry
MPHLCCUG_02059 CDS
T04305
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mphl
Mycolicibacterium phlei
Pathway
mphl00290
Valine, leucine and isoleucine biosynthesis
mphl00660
C5-Branched dibasic acid metabolism
mphl01100
Metabolic pathways
mphl01110
Biosynthesis of secondary metabolites
mphl01210
2-Oxocarboxylic acid metabolism
mphl01230
Biosynthesis of amino acids
Module
mphl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mphl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MPHLCCUG_02059 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MPHLCCUG_02059 (leuC)
Enzymes [BR:
mphl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MPHLCCUG_02059 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MPHLCCUG_02059 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AMO60877
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Position
2121609..2123048
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AA seq
479 aa
AA seq
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MSTHVSDKPRTLAEKVWDDHVVVPGSGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLAG
RKVRRPDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRRNCEEFGIRLHPMGDVEQGIV
HIIGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLSLRPFKTMAV
NVDGALPPGVSAKDIVLAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSIEAGA
RAGMIAPDDTTFEYLRGRPHAPKGEQWDRAVEAWRQLRTDEGAEFDTEVYIDASTLSPFV
TWGTNPGQGVPLSASVPDPEMMTDDAERLAAQKALTYMGLTPGTPMRDIAVDTVFVGSCT
NGRIEDLRVVADVLRGRKVADGVRMLIVPGSMRVRQQAEEEGLGEIFVAAGAEWRQAGCS
MCLGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLTA
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgtccacgcacgtgtccgacaagccgcgcaccctggccgagaaggtatgggacgaccac
gtcgtcgtccctggctccggtgagggggcggcacgtgagcccgacctgatctacatcgac
ctccacctcgtgcacgaggtgaccagtccgcaggccttcgacgggctgcggctggcggga
cggaaggtgcgcaggcccgatctcacgatcgccaccgaggaccacaacgtgccgacgatc
gacatcgacaagccgatcgccgatccggtgtcgcgcactcaggtcgagaccctgcggcgc
aactgcgaggagttcggcatccggctgcacccgatgggcgacgtcgaacagggcatcgtg
cacatcatcggaccgcagctcggcctgacccagccgggtatgacgatcgtctgtggtgac
agccacacctcgacgcacggtgcgttcggcgcactggcgatgggcatcggcacatccgag
gtcgagcatgtgcttgcgacacagacgctttctttgcggccgttcaagacgatggcggtc
aacgtcgacggcgcgctgccgcccggagtgagcgccaaggacatcgtgctggcggtgatc
gcgaagatcggcaccgggggtggccagggtcacgtcatcgagtaccgcggcagcgccatc
gaatcgctgtcgatggagggccggatgacggtctgcaacatgagcatcgaggccggtgcc
cgcgccggcatgatcgcccccgacgacaccactttcgagtatctgcgcggccgtccgcac
gccccgaagggtgagcagtgggaccgcgccgtcgaggcctggcggcagttgcgcaccgac
gagggcgccgaattcgacaccgaggtctacatcgacgcctcgacgctgagcccgttcgtc
acctggggcaccaacccggggcagggcgttccgctgtcggcctcggttccggatcccgag
atgatgaccgacgacgccgagcgactggccgcccaaaaggccttgacctatatgggtctt
accccgggaaccccgatgcgtgacatcgccgtcgacaccgtgttcgtcggctcgtgcacc
aacggccgcatcgaggatctgcgtgtcgtggccgacgtgctgcgcggccgcaaggtcgcc
gacggcgtgcggatgctcatcgtgccgggctcaatgcgggtgcggcagcaggccgaagag
gaaggcctgggtgagatcttcgtcgcagccggcgccgagtggcggcaggccggttgttcg
atgtgccttggcatgaatccagatcagctctcgcccggacagcgctgcgcgtccacctcc
aaccgcaatttcgagggccgccaaggcaagggcgggcgcacccacctggtctcgcccgcc
gtcgcggccgccaccgccgtgcgcggcaccctgtcctcgcccgccgacctgaccgcctga
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