Mycolicibacterium phocaicum: MPHO_46670
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Entry
MPHO_46670 CDS
T07283
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mphu
Mycolicibacterium phocaicum
Pathway
mphu00860
Porphyrin metabolism
mphu01100
Metabolic pathways
mphu01110
Biosynthesis of secondary metabolites
mphu01120
Microbial metabolism in diverse environments
mphu01240
Biosynthesis of cofactors
Module
mphu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mphu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mphu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MPHO_46670 (hemD)
Enzymes [BR:
mphu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MPHO_46670 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MPHO_46670 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBZ57675
UniProt:
A0A7I7ZTV8
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All DBs
Position
4838708..4840381
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AA seq
557 aa
AA seq
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MRKQHKPGRITFVGSGPGDPGLLTTRARNVLAHAALVFTDPDVPEAVLALIGTDLPPTSG
PHPADAEPAADAKADDAAAPAPAAAPTMTFPHGVDVRPALGDPTEVAKLLIAEAKTGVDV
VRLVAGDPLSVDSVITEVNALAKTAAHFELVPGLPSSTAVPTYAGLPVGSSHTVADVRGD
VDWAALAAAPGPLILHATVSHLPDAARTLIEYGLTDNTPCVVTANGTTCQQRSIETTLAG
LLDKAVLEKPVGPEPVGPLAGPLVVTIGKTVAHRAKLNWWESRSLYGWTVLVPRTKDQAG
EMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKF
NEFGLDARAFSGVKIACVGQATADKVRAFGINPELVPAGEQSSLGLLDEFPDYDEIFDPV
NRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTS
SSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVEALAEHAAR
LRAEGALPPPRKKSRRR
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
gtgcgtaagcagcacaagcccggccgcatcacctttgtcggttccggccccggtgacccg
ggcctgttgacgacgcgtgcgcggaacgttttggcgcatgcggcattggtcttcaccgat
cctgatgtgcccgaggcggtgctggcgctgatcggcaccgacctgccgccgacgtccggg
ccgcacccggccgacgccgagccggctgccgacgccaaggccgacgacgctgccgcgccg
gctccggccgccgcgcccaccatgacgttcccgcacggtgtcgacgtccgccccgcgctg
ggcgaccccaccgaggtggcgaagctgctcatcgccgaggcgaagaccggtgtcgacgtc
gtgcgtctggtcgccggcgacccgctgtcggtcgattcggtcatcaccgaggtgaacgcc
ctggccaagaccgcggcgcacttcgagctggtgccgggcctgccgtcgtcgacggcggtg
cccacctacgcgggcctgcccgtcggctcgtcgcacaccgtggccgacgtccgcggtgac
gtcgactgggccgcgctggccgccgcccccgggccgctgatcctgcacgcgacggtgtcg
cacctgccggacgccgcccgcaccctgatcgaatacggcctcaccgacaacaccccgtgt
gtcgtgacggccaacggcaccacctgccagcagcggtcgatcgagaccacgctggccggg
ctgctggacaaggccgtgctggagaagccggtcggccccgagccggtcggtccgctggcg
ggcccgctggtcgtgaccatcggcaagaccgtggcgcaccgggccaagctgaactggtgg
gagagccgctcgctgtacggctggaccgtgctggtgccgcggaccaaggaccaggccggc
gagatgagcgatcgtctcgtgggccacggcgccctgccgatcgaggtgccgaccatcgcg
gtcgagccgccgcgcagccccgcccagatggagcgcgcggtcaagggtctggtcgacggc
cgcttccagtgggtcgtgttcacctccaccaacgcggtgcgtgcggtgtgggagaagttc
aacgagttcggtctggacgcccgcgcgttctccggtgtgaagatcgcgtgcgtcggtcag
gccaccgcggacaaggtgcgcgcgttcggcatcaaccccgagctggtgcctgccggtgag
cagtcgtcgctgggcctgctggacgaattcccggactacgacgagattttcgacccggtg
aaccgggtgctgctgccgcgcgccgacatcgccaccgagacgctggccgagggcctgcgc
gagcgtggctgggagatcgaggacgtcacggcctaccggaccgtccgggcggcaccgccg
ccggcgcacacccgcgagatgatcaagaccggtggtttcgacgccgtctgcttcacctcg
agctccacggtgcgcaacctggtcggcatcgccggcaaaccgcacgcccggaccatcgtc
gcctgcatcggcccgaaaaccgctgaaaccgcagccgaattcggcctgcgcgtggacgtg
cagccggagaccgccgcagtcggcccgctggtcgaggcgctggccgagcacgccgctcgg
ctccgggccgagggtgcgttgccaccgccgcgtaagaagagccggcgccgctaa
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