Mycobacterium pseudoshottsii: MPSD_09740
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Entry
MPSD_09740 CDS
T07300
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mpse
Mycobacterium pseudoshottsii
Pathway
mpse00860
Porphyrin metabolism
mpse01100
Metabolic pathways
mpse01110
Biosynthesis of secondary metabolites
mpse01120
Microbial metabolism in diverse environments
mpse01240
Biosynthesis of cofactors
Module
mpse_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mpse_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mpse00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MPSD_09740 (hemD)
Enzymes [BR:
mpse01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MPSD_09740 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MPSD_09740 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBA86651
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All DBs
Position
complement(1064681..1066357)
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AA seq
558 aa
AA seq
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MMTRGRKPRPGRITYVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPESVLALIGNDLPP
VSGPAPATAVADNADAATGGPAEDESDQAVPAVVSSGPDIRPALGDPTEVAKTLTAEARS
GADVVRLVAGDPMSVDAVIAEVNAITRSHLQIEILPGLAATSAVPTYAGLPLGSAHTVAD
VRGDVDWEALAAAPGPLILQATASHLADAARTLVEHELADTTPCVVTAHGTTCQQRSVET
TLQGLTDPAILGGTDPAGPLTGPLVVTIGKTVSNRAKLNWWESRALYGWTVLVPRTKDQA
GEMSERLTSYGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEK
FGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDEFPPYDSIFDP
VNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFT
SSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAA
RLRAEGALPPPRKKSRRR
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgcgagggcgcaagccgaggccgggccgcattacttatgtgggctctggccca
ggtgacccgggtctgttgaccacacgggccgccgcggtactggcgaacgccgccctggtg
ttcacggaccccgatgtgcctgaatcggtgctggccctgatcggtaacgatctgccgccc
gtctccgggccggcgcccgcgactgcagtggccgacaatgctgacgctgcgaccggcggc
cccgccgaggatgagtccgaccaggcggttccggcggtggtctctagtggtccggacatc
cgcccggcgctgggtgatcccaccgaagttgccaaaacgctgaccgccgaagcccgttcg
ggcgccgacgtggtgcgtttggtggccggtgacccgatgtcggtggacgcggtgatcgcc
gaggtcaacgccattacccgcagccacctgcagatcgagatcctgcccggtctggcggca
accagcgcggtcccgacctatgcgggactgcccctgggctccgcgcacacggttgccgac
gtgcgtggcgacgtggactgggaggcgctggccgccgcaccgggtccgctgatcctgcag
gccaccgcgtcacatctggctgacgcggcccgcacgctggttgagcacgagctggcggac
acaacgccgtgcgtggtgaccgcgcacggaaccacctgccaacagcgctcggtggaaacc
accctgcaggggctgaccgatccggccatcctgggtggaaccgaccctgccggcccgctg
accgggccgctggtggtgaccatcggcaagaccgtgagcaatcgcgccaagctgaactgg
tgggagagccgggcactgtacggctggaccgtattggtaccccgaaccaaagaccaggcc
ggcgaaatgagcgagcggctgacgtcctacggcgccctgccggtcgaggtgccgacgatc
gccgtcgaaccgccgcgcagcccggcgcagatggaacgcgcggtcaaaggcctggtcgac
ggccggttccaatgggtcgtgttcacctccaccaacgccgtgcgcgcggtgtgggagaag
ttcggcgagttcggcctggatgcccgggcgttctccggagtgaagatcgcctgtgtgggc
gagtcgactgccgaccgggttcgcgctttcgggatcagcccggagctggtcccggccggg
gaacagtcctcgctgggcctgctggacgaattcccgccctacgacagcattttcgatccg
gtcaaccgggtgttgctgccgcgcgctgacatcgccaccgagacgctggccgaggggctg
cgcgagcgtggctgggagatcgaggacgtgacggcctaccgcacggtgcgggccgctccg
ccgccggcggccacccgcgagatgatcaagacgggcggtttcgacgcggtctgcttcacc
tcgagttctacggtgcgcaatctggtcggtatcgccggtaagccgcacgcgcggaccatc
atcgcctgcatcggacccaagaccgccgaaacggccgccgagttcgggctccgggtggat
gtccaacccgagactgccgcggtgggtccgctggtggacgcgctggccgagcacgccgcc
cggctgcgcgccgaaggagccctgcccccgcctcgcaagaagagtcgccggcgctag
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